Convergent evolution of tRNA gene targeting preferences in compact genomes [0.03%]
紧凑型基因组中tRNA基因靶向偏好的汇聚进化
Thomas Spaller,Eva Kling,Gernot Glöckner et al.
Thomas Spaller et al.
Background: In gene-dense genomes, mobile elements are confronted with highly selective pressure to amplify without causing excessive damage to the host. The targeting of tRNA genes as potentially safe integration sites h...
John L Goodier
John L Goodier
Retrotransposons have generated about 40 % of the human genome. This review examines the strategies the cell has evolved to coexist with these genomic "parasites", focussing on the non-long terminal repeat retrotransposons of humans and mic...
Pinpointing the vesper bat transposon revolution using the Miniopterus natalensis genome [0.03%]
利用奈拉蝙蝠基因组确定伏翼蝠转座子革命的位置
Roy N Platt nd,Sarah F Mangum,David A Ray
Roy N Platt nd
Background: Around 40 million years ago DNA transposons began accumulating in an ancestor of bats in the family Vespertilionidae. Since that time, Class II transposons have been continuously reinvading and accumulating in...
Identification of polymorphic SVA retrotransposons using a mobile element scanning method for SVA (ME-Scan-SVA) [0.03%]
利用移动元件扫描法鉴定多态性SVA反向重复序列元件
Hongseok Ha,Jui Wan Loh,Jinchuan Xing
Hongseok Ha
Background: Mobile element insertions are a major source of human genomic variation. SVA (SINE-R/VNTR/Alu) is the youngest retrotransposon family in the human genome and a number of diseases are known to be caused by SVA ...
Virus-like attachment sites as structural landmarks of plants retrotransposons [0.03%]
植物类病毒附着位点的结构标志及其在线粒体基因组中的作用
Edgar Andres Ochoa Cruz,Guilherme Marcello Queiroga Cruz,Andréia Prata Vieira et al.
Edgar Andres Ochoa Cruz et al.
Background: The genomic data available nowadays has enabled the study of repetitive sequences and their relationship to viruses. Among them, long terminal repeat retrotransposons (LTR-RTs) are the largest component of mos...
Mechanism of spacer integration links the CRISPR/Cas system to transposition as a form of mobile DNA [0.03%]
间隔区插入机制将CRISPR / Cas系统与转座作用联系起来作为可移动DNA的形式
Fred Dyda,Alison B Hickman
Fred Dyda
It has recently become clear that many bacterial and archaeal species possess adaptive immune systems. These are typified by multiple copies of DNA sequences known as clustered regularly interspaced short palindromic repeats (CRISPRs). Thes...
Distribution of the DNA transposon family, Pokey in the Daphnia pulex species complex [0.03%]
水蚤(Daphnia pulex)物种复合群中DNA转座子家族Pokey的分布规律研究
Shannon H C Eagle,Teresa J Crease
Shannon H C Eagle
Background: The Pokey family of DNA transposons consists of two putatively autonomous groups, PokeyA and PokeyB, and two groups of Miniature Inverted-repeat Transposable Elements (MITEs), mPok1 and mPok2. This TE family i...
Georgios Markopoulos,Dimitrios Noutsopoulos,Stefania Mantziou et al.
Georgios Markopoulos et al.
Background: Retrotransposons are mobile elements that have a high impact on shaping the mammalian genomes. Since the availability of whole genomes, genomic analyses have provided novel insights into retrotransposon biolog...
Dustin C Hancks,Haig H Kazazian Jr
Dustin C Hancks
Over evolutionary time, the dynamic nature of a genome is driven, in part, by the activity of transposable elements (TE) such as retrotransposons. On a shorter time scale it has been established that new TE insertions can result in single-g...
The endonuclease domain of the LINE-1 ORF2 protein can tolerate multiple mutations [0.03%]
线粒体DNA多态性影响轻链RNA合成及氧化磷酸化相关蛋白表达
Kristine J Kines,Mark Sokolowski,Dawn L deHaro et al.
Kristine J Kines et al.
Background: Approximately 17 % of the human genome is comprised of the Long INterspersed Element-1 (LINE-1 or L1) retrotransposon, the only currently active autonomous family of retroelements. Though L1 elements have help...