Viral communities of the human gut: metagenomic analysis of composition and dynamics [0.03%]
人肠道病毒群落：组成与动态的元基因组分析
Varun Aggarwala,Guanxiang Liang,Frederic D Bushman
Varun Aggarwala
Background: The numerically most abundant biological entities on Earth are viruses. Vast populations prey on the cellular microbiota in all habitats, including the human gut. ...
Evolutionary history of the mariner element galluhop in avian genomes [0.03%]
鸟类基因组中mariner元件galluhop的进化历史
Natasha Avila Bertocchi,Fabiano Pimentel Torres,Analía Del Valle Garnero et al.
Natasha Avila Bertocchi et al.
Background: Transposable elements (TEs) are highly abundant genomic parasites in eukaryote genomes. Although several genomes have been screened for TEs, so far very limited information is available regarding avian TEs and...
Targeted identification of TE insertions in a Drosophila genome through hemi-specific PCR [0.03%]
利用半特异性PCR鉴定果蝇基因组中的转座元件插入点
Shuo Zhang,Erin S Kelleher
Shuo Zhang
Background: Transposable elements (TEs) are major components of eukaryotic genomes and drivers of genome evolution, producing intraspecific polymorphism and interspecific differences through mobilization and non-homologou...
Discovery of rare, diagnostic Alu Yb8/9 elements in diverse human populations [0.03%]
稀有诊断性Alu Yb8/9元素在不同人类群体中的发现
Julie Feusier,David J Witherspoon,W Scott Watkins et al.
Julie Feusier et al.
Background: Polymorphic human Alu elements are excellent tools for assessing population structure, and new retrotransposition events can contribute to disease. Next-generation sequencing has greatly increased the potentia...
Dynamic silencing of somatic L1 retrotransposon insertions reflects the developmental and cellular contexts of their genomic integration [0.03%]
体细胞L1长散在核元件插入的动态沉默反映了其基因组整合的发育和细胞背景
Manoj Kannan,Jingfeng Li,Sarah E Fritz et al.
Manoj Kannan et al.
Background: The ongoing mobilization of mammalian transposable elements (TEs) contributes to natural genetic variation. To survey the epigenetic control and expression of reporter genes inserted by L1 retrotransposition i...
Evolutionary history of LTR-retrotransposons among 20 Drosophila species [0.03%]
20个果蝇物种的LTR逆转座子的进化历史
Nicolas Bargues,Emmanuelle Lerat
Nicolas Bargues
Background: The presence of transposable elements (TEs) in genomes is known to explain in part the variations of genome sizes among eukaryotes. Even among closely related species, the variation of TE amount may be strikin...
Insertion and deletion polymorphisms of the ancient AluS family in the human genome [0.03%]
人类基因组中古老AluS族的插入和缺失多态性
Maria S Kryatova,Jared P Steranka,Kathleen H Burns et al.
Maria S Kryatova et al.
Background: Polymorphic Alu elements account for 17% of structural variants in the human genome. The majority of these belong to the youngest AluY subfamilies, and most structural variant discovery efforts have focused on...
LoRTE: Detecting transposon-induced genomic variants using low coverage PacBio long read sequences [0.03%]
基于低覆盖率PacBio长读测序检测转座子诱导的基因组变异(LoRTE)
Eric Disdero,Jonathan Filée
Eric Disdero
Background: Population genomic analysis of transposable elements has greatly benefited from recent advances of sequencing technologies. However, the short size of the reads and the propensity of transposable elements to n...
Kirill Ustyantsev,Alexandr Blinov,Georgy Smyshlyaev
Kirill Ustyantsev
Background: Retrotransposons comprise a ubiquitous and abundant class of eukaryotic transposable elements. All members of this class rely on reverse transcriptase activity to produce a DNA copy of the element from the RNA...
Considerations and complications of mapping small RNA high-throughput data to transposable elements [0.03%]
关于绘制small RNA高通量数据到转座元件上的考虑和复杂性
Alexandros Bousios,Brandon S Gaut,Nikos Darzentas
Alexandros Bousios
Background: High-throughput sequencing (HTS) has revolutionized the way in which epigenetic research is conducted. When coupled with fully-sequenced genomes, millions of small RNA (sRNA) reads are mapped to regions of int...