Expression of endogenous retroviral elements is associated with extracellular matrix remodeling in prostate cancer [0.03%]
内源性逆转录病毒元件与前列腺癌细胞外基质重塑有关
Emily C Williams,Dewanga R Mayarata,Anelia Horvath et al.
Emily C Williams et al.
How endogenous retroviral elements (ERVs), a family of transposable elements, may promote tumor progression is not well understood. Tripartite motif-containing 28 (TRIM28/TIF1b/KAP1) is a key transcriptional co-repressor protein that repres...
Transposable elements: a key piece in the genomic evolution and adaptation of Myrtaceae species [0.03%]
转座元件：Myrtaceae物种基因组进化和适应的关键因素
Edgar Luis Waschburger,João Pedro Carmo Filgueiras,Henrique da Rocha Moreira Antoniolli et al.
Edgar Luis Waschburger et al.
Diverging transposon activity among polar bear sub-populations inhabiting different climate zones [0.03%]
栖居于不同气候区域的北极熊亚种群之间的转座子活性差异性增强
Alice M Godden,Benjamin T Rix,Simone Immler
Alice M Godden
A new subpopulation of polar bears (Ursus maritimus) was recently discovered in the South-East of Greenland. This isolated colony inhabits a warmer climate zone, akin to the predicted future environments of polar bears with vastly reduced s...
Heat-induced transcriptional activation of LTR retrotransposons in the regenerative flatworm Macrostomum lignano [0.03%]
热诱导的ltr反转录转座子在再生平滑虫macrostomum lignano中的转录活化
Kirill Ustyantsev,Stijn Mouton,Mattia Stranges et al.
Kirill Ustyantsev et al.
ColabCuraTE: an easy-to-use, web-based pipeline for the manual curation of transposable elements [0.03%]
ColabCuraTE：一种用于转座子手动注释的简便网络流程管道
Scott L Travers,Abbas Khansa,Christopher E Ellison
Scott L Travers
Background: Transposable elements (TEs) are widespread mobile DNA sequences that shape genome structure, function, and evolution. Although automated tools exist for the de novo identification and classification of TEs, th...
Identification of novel regulators of LINE-1 expression via CRISPR/Cas9 screening [0.03%]
通过CRISPR/Cas9筛选鉴定LINE-1表达的新调节因子
Ozgur Oksuz,Chong Chu,Cedric Arisdakessian et al.
Ozgur Oksuz et al.
Background: Long Interspersed Nuclear Elements-1 (LINE-1, L1) are transposable elements that make up roughly 17% of the human genome. These elements can copy and insert themselves into new genomic locations (Kazazian and ...
Liver-specific enhancers evolved from independent episodes of MITE domestication in Xenopus tropicalis [0.03%]
热带爪蟾肝脏特异性启动子源自MITE基因组插入事件
Japhet Rojas,Héctor Castillo,Marco Mundaca et al.
Japhet Rojas et al.
Transposable elements (TEs) occupy a significant fraction of a wide variety of eukaryotic genomes and can be domesticated into functional sequences harbouring a coding or regulatory potential. While studies in mammals have revealed that ret...
Endogenous retroviruses in aging and cancer: from genomic defense to oncogenic activation [0.03%]
内源性逆转录病毒与衰老和癌症：从基因组防御到致癌激活
Gabriel Arantes Dos Santos,Nathália Da Roz D&#x;Alessandre,Gabriela Der Agopian Guardia et al.
Gabriel Arantes Dos Santos et al.
Nearly half of the human genome consists of transposable elements, among which endogenous retroviruses, remnants of ancient retroviral infections, represent some of the most evolutionarily intriguing due to their paradoxical functional dual...
Maxfield M G Kelsey,Radha L Kalekar,John M Sedivy
Maxfield M G Kelsey
Background: The recognition that transposable elements (TEs) play important roles in many biological processes has elicited growing interest in analyzing sequencing data derived from this 'dark genome'. This goal is compl...
FoTeRs: a novel family of telomere-associated retrotransposons in Fusarium oxysporum [0.03%]
FoTeRs：存在于尖孢镰刀菌中的新型端粒相关逆转座子家族
Sahar Salimi,Mostafa Rahnama
Sahar Salimi
Transposable elements (TEs) are dynamic components of eukaryotic genomes, playing a crucial role in genome evolution and plasticity, particularly in unstable regions such as chromosome ends. In the globally significant fungal pathogen Fusar...