Transcriptome analyses of tumor-adjacent somatic tissues reveal genes co-expressed with transposable elements [0.03%]
肿瘤相邻体组织的转录组分析揭示了与转座元件共表达的基因
Nicky Chung,G M Jonaid,Sophia Quinton et al.
Nicky Chung et al.
Background: Despite the long-held assumption that transposons are normally only expressed in the germ-line, recent evidence shows that transcripts of transposable element (TE) sequences are frequently found in the somatic...
Characterization of the endogenous retrovirus insertion in CYP19A1 associated with henny feathering in chicken [0.03%]
与鸡母羽表型相关的CYP19A1基因内源性病毒插入位点的特征分析
Jingyi Li,Brian W Davis,Patric Jern et al.
Jingyi Li et al.
Background: Henny feathering in chickens is determined by a dominant mutation that transforms male-specific plumage to female-like plumage. Previous studies indicated that this phenotype is caused by ectopic expression in...
Variable genome evolution in fungi after transposon-mediated amplification of a housekeeping gene [0.03%]
异染色质区组胺酸tRNA转座子引发的保致基因扩增导致隐球菌基因组和宿主适应性的变化
Braham Dhillon,Gert H J Kema,Richard C Hamelin et al.
Braham Dhillon et al.
Background: Transposable elements (TEs) can be key drivers of evolution, but the mechanisms and scope of how they impact gene and genome function are largely unknown. Previous analyses revealed that TE-mediated gene ampli...
A human endogenous retrovirus encoded protease potentially cleaves numerous cellular proteins [0.03%]
一种人类内源性逆转录病毒编码的蛋白酶有可能切割多种细胞蛋白
Giuseppe Rigogliuso,Martin L Biniossek,John L Goodier et al.
Giuseppe Rigogliuso et al.
Background: A considerable portion of the human genome derives from retroviruses inherited over millions of years. Human endogenous retroviruses (HERVs) are usually severely mutated, yet some coding-competent HERVs exist....
Nuclear export signal (NES) of transposases affects the transposition activity of mariner-like elements Ppmar1 and Ppmar2 of moso bamboo [0.03%]
竹类蒲公英转座子Ppmar1和Ppmar2的转座酶的核输出信号影响其转座活性
Muthusamy Ramakrishnan,Ming-Bing Zhou,Chun-Fang Pan et al.
Muthusamy Ramakrishnan et al.
Ppmar1 and Ppmar2 are two active mariner-like elements (MLEs) cloned from moso bamboo (Phyllostachys edulis (Carrière) J. Houz) genome possessing transposases that harbour nuclear export signal (NES) domain, but not any nuclear localizatio...
Study of VIPER and TATE in kinetoplastids and the evolution of tyrosine recombinase retrotransposons [0.03%]
关于锦囊藻纲中VIPER和TATE的研究以及酪氨酸重组酶类反转录转座子的进化研究
Yasmin Carla Ribeiro,Lizandra Jaqueline Robe,Danila Syriani Veluza et al.
Yasmin Carla Ribeiro et al.
Background: Kinetoplastids are a flagellated group of protists, including some parasites, such as Trypanosoma and Leishmania species, that can cause diseases in humans and other animals. The genomes of these species enclo...
Study of VIPER and TATE in kinetoplastids and the evolution of tyrosine recombinase retrotransposons [0.03%]
关于锦鸡儿和苔属鞭毛纲原生动物的研究以及酪氨酸重组酶逆转录转座子的进化研究
Yasmin Carla Ribeiro,Lizandra Jaqueline Robe,Danila Syriani Veluza et al.
Yasmin Carla Ribeiro et al.
Background: Kinetoplastids are a flagellated group of protists, including some parasites, such as Trypanosoma and Leishmania species, that can cause diseases in humans and other animals. The genomes of these species enclo...
Convergence in LINE-1 nucleotide variations can benefit redundantly forming triplexes with lncRNA in mammalian X-chromosome inactivation [0.03%]
LINE-1核苷酸变异的趋同演化有利于其在哺乳动物X染色体失活中与长非编码RNA形成冗余三链复合物
Yoko Matsuno,Takefumi Yamashita,Michiru Wagatsuma et al.
Yoko Matsuno et al.
Background: Associations between X-inactive transcript (Xist)-long noncoding RNA (lncRNA) and chromatin are critical intermolecular interactions in the X-chromosome inactivation (XCI) process. Despite high-resolution anal...
Convergence in LINE-1 nucleotide variations can benefit redundantly forming triplexes with lncRNA in mammalian X-chromosome inactivation [0.03%]
LINE-1核苷酸变异的趋同进化有利于其与哺乳动物X染色体失活过程中的长非编码RNA形成冗余三链复合物
Yoko Matsuno,Takefumi Yamashita,Michiru Wagatsuma et al.
Yoko Matsuno et al.
Background: Associations between X-inactive transcript (Xist)-long noncoding RNA (lncRNA) and chromatin are critical intermolecular interactions in the X-chromosome inactivation (XCI) process. Despite high-resolution anal...
Diseases of the nERVous system: retrotransposon activity in neurodegenerative disease [0.03%]
神经系统的疾病：逆转座子在神经退行性疾病中的作用
Oliver H Tam,Lyle W Ostrow,Molly Gale Hammell
Oliver H Tam
Transposable Elements (TEs) are mobile genetic elements whose sequences constitute nearly half of the human genome. Each TE copy can be present in hundreds to thousands of locations within the genome, complicating the genetic and genomic st...