Unbiased profiling of CRISPR RNA-guided transposition products by long-read sequencing [0.03%]
通过长读测序对CRISPR RNA引导的转座产物进行无偏差分析
Phuc Leo H Vo,Christopher Acree,Melissa L Smith et al.
Phuc Leo H Vo et al.
Bacterial transposons propagate through either non-replicative (cut-and-paste) or replicative (copy-and-paste) pathways, depending on how the mobile element is excised from its donor source. In the well-characterized E. coli transposon Tn7,...
The unusual structure of the PiggyMac cysteine-rich domain reveals zinc finger diversity in PiggyBac-related transposases [0.03%]
独特的PiggyMac半胱氨酸富集区结构揭示了与PiggyBac相关的转座酶的锌指多样性
Marc Guérineau,Luiza Bessa,Séverine Moriau et al.
Marc Guérineau et al.
Background: Transposons are mobile genetic elements that colonize genomes and drive their plasticity in all organisms. DNA transposon-encoded transposases bind to the ends of their cognate transposons and catalyze their m...
The IS6 family, a clinically important group of insertion sequences including IS26 [0.03%]
IS6家族是一组重要的临床插入序列，包括IS26
Alessandro Varani,Susu He,Patricia Siguier et al.
Alessandro Varani et al.
The IS6 family of bacterial and archaeal insertion sequences, first identified in the early 1980s, has proved to be instrumental in the rearrangement and spread of multiple antibiotic resistance. Two IS, IS26 (found in many enterobacterial ...
Nikita S Vassetzky,Sergei A Kosushkin,Vitaly I Korchagin et al.
Nikita S Vassetzky et al.
Background: SINEs comprise a significant part of animal genomes and are used to study the evolution of diverse taxa. Despite significant advances in SINE studies in vertebrates and higher eukaryotes in general, their own ...
Methylation of rRNA as a host defense against rampant group II intron retrotransposition [0.03%]
宿主通过甲基化rRNA防御过度的第II类内含子逆转录转位现象
Justin M Waldern,Dorie Smith,Carol Lyn Piazza et al.
Justin M Waldern et al.
Background: Group II introns are mobile retroelements, capable of invading new sites in DNA. They are self-splicing ribozymes that complex with an intron-encoded protein to form a ribonucleoprotein that targets DNA after ...
The association of group IIB intron with integrons in hypersaline environments [0.03%]
高盐环境中的组IIb内含子与整合子的关联性研究
Sarah Sonbol,Rania Siam
Sarah Sonbol
Background: Group II introns are mobile genetic elements used as efficient gene targeting tools. They function as both ribozymes and retroelements. Group IIC introns are the only class reported so far to be associated wit...
Transcriptional activity of transposable elements along an elevational gradient in Arabidopsis arenosa [0.03%]
拟南芥转座子在海拔梯度上的转录活性研究
Guillaume Wos,Rimjhim Roy Choudhury,Filip Kolář et al.
Guillaume Wos et al.
Background: Plant genomes can respond rapidly to environmental changes and transposable elements (TEs) arise as important drivers contributing to genome dynamics. Although some elements were reported to be induced by vari...
Jessica L Elmer,Amir D Hay,Noah J Kessler et al.
Jessica L Elmer et al.
Background: Transposable elements (TEs) are enriched in cytosine methylation, preventing their mobility within the genome. We previously identified a genome-wide repertoire of candidate intracisternal A particle (IAP) TEs...
RIP-seq reveals LINE-1 ORF1p association with p-body enriched mRNAs [0.03%]
RIP seq揭示LINE-1 ORF1p与富含p体的mRNA相关性
Erica M Briggs,Wilson McKerrow,Paolo Mita et al.
Erica M Briggs et al.
Background: Long INterspersed Element-1 (LINE-1) is an autonomous retroelement able to "copy-and-paste" itself into new loci of the host genome through a process called retrotransposition. The LINE-1 bicistronic mRNA code...
Kaitlin M Carey,Gilia Patterson,Travis J Wheeler
Kaitlin M Carey
Background: Transposable element (TE) sequences are classified into families based on the reconstructed history of replication, and into subfamilies based on more fine-grained features that are often intended to capture f...