Differential regulation of transposable elements (TEs) during the murine submandibular gland development [0.03%]
小鼠下颌下腺发育过程中可转座元件（TEs）的差异调控
Braulio Valdebenito-Maturana,Francisca Torres,Mónica Carrasco et al.
Braulio Valdebenito-Maturana et al.
The submandibular gland (SG) is a relatively simple organ formed by three cell types: acinar, myoepithelial, and an intricate network of duct-forming epithelial cells, that together fulfills several physiological functions from assisting fo...
Genomic approaches to trace the history of human brain evolution with an emerging opportunity for transposon profiling of ancient humans [0.03%]
利用基因组方法追踪人类大脑进化历史，新兴的古人类转座子分析机会
Yilan Wang,Boxun Zhao,Jaejoon Choi et al.
Yilan Wang et al.
Transposable elements (TEs) significantly contribute to shaping the diversity of the human genome, and lines of evidence suggest TEs as one of driving forces of human brain evolution. Existing computational approaches, including cross-speci...
Unbiased proteomic mapping of the LINE-1 promoter using CRISPR Cas9 [0.03%]
利用CRISPR-Cas9非偏向地绘制LINE-1启动子蛋白质组图谱
Erica M Briggs,Paolo Mita,Xiaoji Sun et al.
Erica M Briggs et al.
Background: The autonomous retroelement Long Interspersed Element-1 (LINE-1) mobilizes though a copy and paste mechanism using an RNA intermediate (retrotransposition). Throughout human evolution, around 500,000 LINE-1 se...
A 192 bp ERV fragment insertion in the first intron of porcine TLR6 may act as an enhancer associated with the increased expressions of TLR6 and TLR1 [0.03%]
猪TLR6基因的第一个内含子中一个ERV片段的插入可能是一个增强子 改变了TLR6和TLR1表达水平
XiaoYan Wang,Zixuan Chen,Eduard Murani et al.
XiaoYan Wang et al.
Background: Toll-like receptors (TLRs) play important roles in building innate immune and inducing adaptive immune responses. Associations of the TLR genes polymorphisms with disease susceptibility, which are the basis of...
Correction to: Upregulation of selected HERVW loci in multiple sclerosis [0.03%]
多发性硬化患者体内某些HERVW基因座的上调表达的订正公告
Sofía Macías-Redondo,Mark Strunk,Alberto Cebollada-Solanas et al.
Sofía Macías-Redondo et al.
Published Erratum
Mobile DNA. 2021 Aug 11;12(1):19. DOI:10.1186/s13100-021-00247-x 2021
Sofía Macías-Redondo,Mark Strunk,Alberto Cebollada-Solanas et al.
Sofía Macías-Redondo et al.
SINE jumping contributes to large-scale polymorphisms in the pig genomes [0.03%]
猪基因组的大规模多态性受到SINE跳转的贡献
Cai Chen,Enrico D&#x;Alessandro,Eduard Murani et al.
Cai Chen et al.
Background: Molecular markers based on retrotransposon insertion polymorphisms (RIPs) have been developed and are widely used in plants and animals. Short interspersed nuclear elements (SINEs) exert wide impacts on gene a...
TE Hub: A community-oriented space for sharing and connecting tools, data, resources, and methods for transposable element annotation [0.03%]
TE汇编：一个以社区为导向的空间，用于分享和连接转座子注释工具、数据、资源和方法
TE Hub Consortium;Tyler A Elliott,Tony Heitkam,Robert Hubley et al.
TE Hub Consortium;Tyler A Elliott et al.
Transposable elements (TEs) play powerful and varied evolutionary and functional roles, and are widespread in most eukaryotic genomes. Research into their unique biology has driven the creation of a large collection of databases, software, ...
melRNA-seq for Expression Analysis of SINE RNAs and Other Medium-Length Non-Coding RNAs [0.03%]
用于中等长度非编码RNA表达分析的melRNA-seq方法
Yoshinobu Mori,Kenji Ichiyanagi
Yoshinobu Mori
Background: Small interspersed elements (SINEs) are transcribed by RNA polymerase III (Pol III) to produce RNAs typically 100-500 nucleotides in length. Although their RNA abundance can be evaluated by Northern blotting a...
The derepression of transposable elements in lung cells is associated with the inflammatory response and gene activation in idiopathic pulmonary fibrosis [0.03%]
特发性肺纤维化患者肺细胞转座元件去抑制与炎症反应和基因激活有关
Mahboubeh R Rostami,Martina Bradic
Mahboubeh R Rostami
Background: Transposable elements (TEs) are repetitive sequences of viral origin that compose almost half of the human genome. These elements are tightly controlled within cells, and if activated, they can cause changes i...