Analysis of antibiotic resistance gene cassettes in a newly identified Salmonella enterica serovar Gallinarum strain in Korea [0.03%]
韩国新分离鸡副伤寒沙门氏菌菌株耐药基因分析
Thanh Quang Tran,Minyoung Park,Jong Eun Lee et al.
Thanh Quang Tran et al.
Antimicrobial resistant pathogens are a global health threat driven by the indiscriminate use of antimicrobials. Antimicrobial resistance can be acquired by resistance genes encoded by mobile genetic elements. In this study, we identified a...
Telomeric retrotransposons show propensity to form G-quadruplexes in various eukaryotic species [0.03%]
端粒逆转座子在多种真核生物中可形成G-四链体结构
Pavel Jedlička,Viktor Tokan,Iva Kejnovská et al.
Pavel Jedlička et al.
Background: Canonical telomeres (telomerase-synthetised) are readily forming G-quadruplexes (G4) on the G-rich strand. However, there are examples of non-canonical telomeres among eukaryotes where telomeric tandem repeats...
Expression of down-regulated ERV LTR elements associates with immune activation in human small-cell lung cancers [0.03%]
人小细胞肺癌中下调的ERV LTR元件表达与免疫激活相关
Marco Russo,Sara Morelli,Giovanni Capranico
Marco Russo
Small-cell lung cancer (SCLC) is an aggressive cancer characterized by immunosuppressive features leading to poor responses to current immunotherapies. Activation of transposable elements (TE) can trigger an innate immune response, which ca...
Mobility of mPing and its associated elements is regulated by both internal and terminal sequences [0.03%]
mPing及其相关序列的转座活性受内部和末端序列的影响
Priscilla S Redd,Stephanie Diaz,David Weidner et al.
Priscilla S Redd et al.
Background: DNA transposable elements are mobilized by a "cut and paste" mechanism catalyzed by the binding of one or more transposase proteins to terminal inverted repeats (TIRs) to form a transpositional complex. Study ...
CAULIFINDER: a pipeline for the automated detection and annotation of caulimovirid endogenous viral elements in plant genomes [0.03%]
CAULIFINDER：用于检测和标注植物基因组中 Caulimovirid 内源病毒元件的自动化流程
Héléna Vassilieff,Sana Haddad,Véronique Jamilloux et al.
Héléna Vassilieff et al.
Plant, animal and protist genomes often contain endogenous viral elements (EVEs), which correspond to partial and sometimes entire viral genomes that have been captured in the genome of their host organism through a variety of integration m...
Simanti Das,Amanda E Jones,John M Abrams
Simanti Das
Background: LINE-1s, Alus and SVAs are the only retrotransposition competent elements in humans. Their mobilization followed by insertional mutagenesis is often linked to disease. Apart from these rare integration events,...
T3E: a tool for characterising the epigenetic profile of transposable elements using ChIP-seq data [0.03%]
T3E：一种利用ChIP序列数据表征可移动元素的表观遗传谱的工具
Michelle Almeida da Paz,Leila Taher
Michelle Almeida da Paz
Background: Despite the advent of Chromatin Immunoprecipitation Sequencing (ChIP-seq) having revolutionised our understanding of the mammalian genome's regulatory landscape, many challenges remain. In particular, because ...
Recurrent co-domestication of PIF/Harbinger transposable element proteins in insects [0.03%]
昆虫中PIF/哈勃林格转座元件蛋白的反复共 domesticate 化现象
Dragomira N Markova,Fatema B Ruma,Claudio Casola et al.
Dragomira N Markova et al.
Background: Transposable elements (TEs) are selfish DNA sequences capable of moving and amplifying at the expense of host cells. Despite this, an increasing number of studies have revealed that TE proteins are important c...
Giorgia Modenini,Paolo Abondio,Alessio Boattini
Giorgia Modenini
Retrotransposons are genetic elements with the ability to replicate in the genome using reverse transcriptase: they have been associated with the development of different biological structures, such as the Central Nervous System (CNS), and ...
A proteomic screen of Ty1 integrase partners identifies the protein kinase CK2 as a regulator of Ty1 retrotransposition [0.03%]
Ty1整合酶伙伴的蛋白质组筛选确定蛋白激酶CK2是Ty1逆转录转座的调节因子
Anastasia Barkova,Indranil Adhya,Christine Conesa et al.
Anastasia Barkova et al.
Background: Transposable elements are ubiquitous and play a fundamental role in shaping genomes during evolution. Since excessive transposition can be mutagenic, mechanisms exist in the cells to keep these mobile elements...