Blake J Cochran,Thomas W King,Kevin Chemello et al.
Blake J Cochran et al.
Epidemiological studies have identified an inverse association of high-density lipoprotein (HDL) cholesterol with cardiovascular risk. Preclinical studies have shown that HDLs also exhibit cardioprotective functions in cultured cells and an...
Cardiometabolic and renal benefits of sodium-glucose cotransporter 2 inhibitors [0.03%]
钠-葡萄糖协同转运蛋白2抑制剂的心血管代谢及肾脏获益作用
Yong-Ho Lee,Soo Lim,Melanie J Davies
Yong-Ho Lee
The therapeutic scope of sodium-glucose cotransporter 2 (SGLT2) inhibitors has expanded beyond glycaemic regulation in the management of diabetes mellitus. Studies published in the past few years highlight their substantial effect on cardio...
Mechanisms of diabetic kidney disease and established and emerging treatments [0.03%]
糖尿病肾病发病机制及现有和新兴治疗措施
Victor Martinez Leon,Rachel Hilburg,Katalin Susztak
Victor Martinez Leon
Kidney disease is the leading cause of mortality in persons with diabetes mellitus. Diabetic kidney disease (DKD) typically presents with a reduced estimated glomerular filtration rate and, in many but not all cases, with marked proteinuria...
FDA fast-track approval of belzutifan is a milestone in rare cancer therapy [0.03%]
美国食品药品监督管理局为 Belmont 加速审批开辟罕见癌症治疗新纪元
Carlota Arenillas,Rodrigo A Toledo
Carlota Arenillas
Thomas W H Kay,Jennifer J Couper
Thomas W H Kay
Olivia Tysoe
Olivia Tysoe
John A Hawley,Nolan J Hoffman
John A Hawley
Challenges and opportunities of wearable molecular sensors in endocrinology and metabolism [0.03%]
内分泌和代谢领域中可穿戴分子传感器的挑战与机遇
Andreas T Güntner,Philipp A Gerber,Petra S Dittrich et al.
Andreas T Güntner et al.
Wearable technologies that analyse non-conventional biological matrices, such as interstitial fluid, sweat, tears or breath, have the potential to provide longitudinal biomarker data with minimal invasiveness. These data could provide insig...
Patricia Ducy
Patricia Ducy
Unravelling the rise in thyroid cancer incidence and addressing overdiagnosis [0.03%]
揭秘甲状腺癌发病率的上升并解决过度诊断问题
Debbie W Chen,Megan R Haymart
Debbie W Chen
The global incidence of thyroid cancer has risen sharply since the 1980s, whereas thyroid cancer mortality rates have remained relatively stable. Much of the increase in incidence can be attributed to overdiagnosis of small and indolent pap...