Phosphorylation of CENP-C by PLK1 ensures accurate chromosome congression during mitosis [0.03%]
PLK1介导的CENP-C磷酸化保证了有丝分裂中染色体的精准排列
Shanshan He,Cunyu Wang,Hengyi Shao et al.
Shanshan He et al.
Microtubule plus-end tracking protein EB1 orchestrates mitotic progression via liquid-liquid phase separation [0.03%]
EB1通过液-液相分离调控有丝分裂进程
Mengjie Li,Ming Dai,Xing Hong et al.
Mengjie Li et al.
GPI transamidase complex is required for primordial germ cell migration and development in zebrafish [0.03%]
斑马鱼原始生殖细胞迁移和发育需要GPI连接转胺酶复合体
Weiying Zhang,Yaqi Li,Jing Chen et al.
Weiying Zhang et al.
Proteins without transmembrane domains could be anchored to the cell surface for regulating various biological processes when covalently linked to glycosylphosphatidylinositol (GPI) molecules by the GPI transamidase (GPIT) complex. However,...
Zirui Gao,Dandan Wan,Min Luo et al.
Zirui Gao et al.
Tumor immunotherapy has emerged as a formidable strategy, demonstrating substantial achievements in the field of cancer treatment. Despite its remarkable success, intrinsic limitations such as insufficient targeting capabilities, side effec...
DNAJC12 downregulation induces neuroblastoma progression via increased histone H4K5 lactylation [0.03%]
DNAJC12低表达通过增加组蛋白H4K5乳酰化诱导神经母细胞瘤进展
Yaqi Yang,Jiejun Wen,Susu Lou et al.
Yaqi Yang et al.
Neuroblastoma (NB) is the most common extracranial solid tumor in children. Despite treatment advances, the survival rates of high-risk NB patients remain low. This highlights the urgent need for a deeper understanding of the molecular mech...
Serum IL-27 and GDF15 levels in second trimester are associated with adverse pregnancy outcomes [0.03%]
第二孕期血清IL-27和GDF15水平与不良妊娠结局的关系
Xue Li,Luping Liu,Li Jiang et al.
Xue Li et al.
Inhibition of EphA2 by syndecan-4 in wounded skin regulates clustering of fibroblasts [0.03%]
syndecan-4通过抑制EphA2调节伤口皮肤成纤维细胞聚类的作用
Rebecca Brooks,Xianhui Wei,Mang Leng Lei et al.
Rebecca Brooks et al.
Upon injury, fibroblasts in the surrounding tissue become activated, migrating into the wound in a controlled manner. Once they arrive, they contract the wound and remodel the stroma. While certain cell surface receptors promote fibroblast ...
Yangchan Hu,Yuxin Meng,Zirui Zhuang et al.
Yangchan Hu et al.
Poly(ADP-ribose) glycosylhydrolase (PARG) is an enzyme involved in hydrolyzing the ribose-ribose bonds present in poly(ADP-ribose) (PAR), which are primarily found in the nucleus. Along with poly(ADP-ribose) polymerase (PARP), PARG regulate...
Molecular insights into AGS3's role in spindle orientation: a biochemical perspective [0.03%]
AGS3在纺锤体定向中的作用的分子见解：生化视角
Shi Yu,Jie Ji,Jingwei Weng et al.
Shi Yu et al.
The intrinsic regulation of spindle orientation during asymmetric cell division depends on the evolutionarily conserved protein complex LGN (Pins)/NuMA (Mud)/Gα⋅GDP. While the role of LGN and its Drosophila orthologue Pins is well-establi...
Increased serum β-hydroxybutyrate/acetoacetate ratio and aggravated histological liver inflammation in females with metabolic dysfunction-associated steatotic liver disease and polycystic ovary syndrome [0.03%]
代谢紊乱相关性肝病合并多囊卵巢综合征女性患者血清β-羟丁酸/乙酰乙酸比率升高及肝脏病理炎症加重
Xiaopeng Zhu,Guligeina Aikebaier,Xilei Ban et al.
Xiaopeng Zhu et al.