Comments on 'Obstructive sleep apnea syndrome exacerbates NASH progression via selective autophagy-mediated Eepd1 degradation' [0.03%]
关于“阻塞性睡眠呼吸暂停综合征通过选择性自噬介导的Eepd1降解加剧NASH进展”的评论
Jie Xiong,Suzhen Chen,Junli Liu
Jie Xiong
Aurora B/AIR-2 regulates sister centromere resolution and CENP-A/HCP-3 organization to prevent merotelic attachments [0.03%]
Aurora B/AIR-2调节姐妹着丝点的解析及CENP-A / HCP-3的组织防止异极连接形成
Yue Wang,Charmaine Yan Yu Wong,Karen Wing Yee Yuen
Yue Wang
During cell division, the accurate capture of sister kinetochores that are built on the centromeres of chromosomes by microtubules emanating from opposite spindle poles governs faithful chromosome segregation. To ensure sister chromatids se...
Targeting HPV for the prevention, diagnosis, and treatment of Cervical Cancer [0.03%]
人乳头瘤病毒靶向策略在宫颈癌防治中的应用
Huiling Ni,Canhua Huang,Zhi Ran et al.
Huiling Ni et al.
Despite advances in screening and prevention, cervical cancer (CC) remains an unresolved public health issue and poses a significant global challenge, particularly for women in low-income regions. Human papillomavirus (HPV) infection, espec...
Yuanyuan Liu,Bohan Liu,Ruirui Zhang et al.
Yuanyuan Liu et al.
Cohesin is a ring complex closed with SMC-1, SMC-3, and a kleisin subunit, mediating sister chromatid cohesion in mitosis and meiosis. Kleisin N- and C-terminal domains interact with SMC-3 and SMC-1, forming two distinct cohesin gates. Whet...
HDAC7 promotes cardiomyocyte proliferation by suppressing Myocyte Enhancer Factor 2 [0.03%]
组蛋白去乙酰化酶7通过抑制肌细胞增强因子2促进心肌细胞增殖
Jihyun Jang,Mette Bentsen,Jin Bu et al.
Jihyun Jang et al.
Postnatal mammalian cardiomyocytes (CMs) rapidly lose proliferative capacity and exit the cell cycle and undergo further differentiation and maturation. Cell cycle activation has been a major strategy to stimulate postnatal CM proliferation...
Gender differences in the health workforce in China: an analysis of national data [0.03%]
中国卫生劳动力的性别差异：全国数据的分析结果
Wenya Yu,Xiang Liu,Hong Chen et al.
Wenya Yu et al.
Gender differences in the health workforce matter for women's health and healthcare, and is also crucial for both health and economic development. Drawing on limited national gender data from China over the last 10 years, during which the c...
Super-resolution microscopy unveils the nanoscale organization and self-limiting clustering of CD47 in human erythrocytes [0.03%]
超分辨率显微镜揭示人红细胞CD47的纳米尺度组织及自限聚集现象
Jianyu Yang,Fulin Xing,Fen Hu et al.
Jianyu Yang et al.
The transmembrane protein CD47, an innate immune checkpoint protein, plays a pivotal role in preventing healthy erythrocytes from immune clearance. Our study utilized stochastic optical-reconstruction microscopy (STORM) and single-molecule ...
Phu M Huynh,Fenfen Wang,Yu A An
Phu M Huynh
Obesity per se is rapidly emerging all over the planet and further accounts for many other life-threatening conditions, such as diabetes, cardiovascular diseases, and cancers. Decreased oxygen supply or increased relative oxygen consumption...
Yueling Zhu,Shiyan Lin,Lingshen Meng et al.
Yueling Zhu et al.
ATP has been recognized as a hydrotrope in the phase separation process of intrinsically disordered proteins (IDPs). Surprisingly, when using the disordered RG/RGG-rich motif from HNRNPG protein as a model system, we discover a biphasic rel...
HIV-1 inhibits IFITM3 expression to promote the infection of megakaryocytes [0.03%]
HIV-1通过抑制IFITM3的表达促进巨核细胞感染
Cyrine Bentaleb,Souad Adrouche,Jade Finkelstein et al.
Cyrine Bentaleb et al.
Despite an undetectable plasma viral load as a result of antiretroviral therapy, HIV-1-infected individuals with poor immune reconstitution harbor infectious HIV-1 within their platelets. Megakaryocytes, as platelet precursors, are the like...