HIV Glycoprotein Gp120 Impairs Fast Axonal Transport by Activating Tak1 Signaling Pathways [0.03%]
HIV糖蛋白Gp120通过激活TAK1信号通路损害快速轴浆运输
Sarah H Berth,Nichole Mesnard-Hoaglin,Bin Wang et al.
Sarah H Berth et al.
Sensory neuropathies are the most common neurological complication of HIV. Of these, distal sensory polyneuropathy (DSP) is directly caused by HIV infection and characterized by length-dependent axonal degeneration of dorsal root ganglion (...
Assessment of Neuroprotective Properties of Melissa officinalis in Combination With Human Umbilical Cord Blood Stem Cells After Spinal Cord Injury [0.03%]
评估柠檬香蜂草与人脐带血干细胞联合治疗脊髓损伤的神经保护作用
Seyed Ruhollah Hosseini,Gholamreza Kaka,Mohammad Taghi Joghataei et al.
Seyed Ruhollah Hosseini et al.
Introduction: The pathophysiology of spinal cord injury (SCI) has a classically bad prognosis. It has been demonstrated that human umbilical cord blood stem cells (hUCBSCs) and Melissa officinalis (MO) are useful for the ...
Grafted Neural Precursors Integrate Into Mouse Striatum, Differentiate and Promote Recovery of Function Through Release of Erythropoietin in MPTP-Treated Mice [0.03%]
血管化的神经前体细胞移植物在1-甲基-4-苯基-1，2，3，6-四氢吡啶（MPTP）诱导的帕金森病小鼠黑质纹状体中建立并促进功能恢复机制的研究
Stephana Carelli,Toniella Giallongo,Cristina Viaggi et al.
Stephana Carelli et al.
Erythropoietin-releasing neural precursor cells (Er-NPCs) are a subclass of subventricular zone-derived neural progenitors, capable of surviving for 6 hr after death of donor. They present higher neural differentiation. Here, Er-NPCs were s...
Photoperiod Modulates Fast Delayed Rectifier Potassium Currents in the Mammalian Circadian Clock [0.03%]
光周期调节哺乳动物昼夜钟中的快速延迟整流钾电流
Sahar Farajnia,Johanna H Meijer,Stephan Michel
Sahar Farajnia
One feature of the mammalian circadian clock, situated in the suprachiasmatic nucleus (SCN), is its ability to measure day length and thereby contribute to the seasonal adaptation of physiology and behavior. The timing signal from the SCN, ...
Enhanced Histochemical Detection of Iron in Paraffin Sections of Mouse Central Nervous System Tissue: Application in the APP/PS1 Mouse Model of Alzheimer's Disease [0.03%]
小鼠中枢神经系统组织石蜡切片中铁染色的改进及在阿尔茨海默病APP/PS1 模型中的应用
Scott A Sands,Regis Leung-Toung,Yingsheng Wang et al.
Scott A Sands et al.
Histochemical methods of detecting iron in the rodent brain result mainly in the labeling of oligodendrocytes, but as all cells utilize iron, this observation suggests that much of the iron in the central nervous system goes undetected. Par...
Transcriptional Fingerprint of Hypomyelination in Zfp191null and Shiverer (Mbpshi) Mice [0.03%]
锌指蛋白191基因敲除和震颤素小鼠少突胶质细胞转录组测序及生物信息学分析
Joshua D Aaker,Benayahu Elbaz,Yuwen Wu et al.
Joshua D Aaker et al.
The transcriptional program that controls oligodendrocyte maturation and central nervous system (CNS) myelination has not been fully characterized. In this study, we use high-throughput RNA sequencing to analyze how the loss of a key transc...
Intranasal Administration of Interferon Beta Attenuates Neuronal Apoptosis via the JAK1/STAT3/BCL-2 Pathway in a Rat Model of Neonatal Hypoxic-Ischemic Encephalopathy [0.03%]
鼻内给药干扰素β通过JAK1/STAT3/BCL-2通路减轻新生儿缺氧缺血性脑病大鼠模型的神经元凋亡
Brandon J Dixon,Di Chen,Yang Zhang et al.
Brandon J Dixon et al.
Neonatal hypoxic-ischemic encephalopathy (HIE) is an injury that often leads to detrimental neurological deficits. Currently, there are no established therapies for HIE and it is critical to develop treatments that provide protection after ...
Anti-Sulfoglucuronosyl Paragloboside Antibody: A Potential Serologic Marker of Amyotrophic Lateral Sclerosis [0.03%]
抗硫磺葡萄糖氨基para-球甘露聚糖抗体可能是运动神经元病的血清标志物
Dongpei Li,Seigo Usuki,Brandy Quarles et al.
Dongpei Li et al.
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive degeneration of upper and lower motor neurons. Although the etiology of ALS is obscure, genetic studies of familiar ALS suggest a multifactorial...
Donají Chi-Castañeda,Arturo Ortega
Donají Chi-Castañeda
Circadian rhythms are periodic patterns in biological processes that allow the organisms to anticipate changes in the environment. These rhythms are driven by the suprachiasmatic nucleus (SCN), the master circadian clock in vertebrates. At ...
HIV-1 Tat Inhibits Autotaxin Lysophospholipase D Activity and Modulates Oligodendrocyte Differentiation [0.03%]
HIV-1蛋白Tat抑制自主迁移素的LPLD活性并调节少突胶质细胞分化
Natalie A Wheeler,Babette Fuss,Pamela E Knapp et al.
Natalie A Wheeler et al.
White matter injury has been frequently reported in HIV+ patients. Previous studies showed that HIV-1 Tat (transactivator of transcription), a viral protein that is produced and secreted by HIV-infected cells, is toxic to young, immature ol...