Alternative Method to Detect Neuronal Degeneration and Amyloid β Accumulation in Free-Floating Brain Sections With Fluoro-Jade [0.03%]
一种用于检测漂浮脑切片中神经元退行性变和淀粉样蛋白β聚集的替代方法
Irene L Gutiérrez,Marta González-Prieto,Borja García-Bueno et al.
Irene L Gutiérrez et al.
Fluoro-Jade is a fluorescein-derived fluorochrome which specifically binds to damaged neurons. Due to this characteristic, it is commonly used for the histochemical detection and quantification of neurodegeneration in mounted brain sections...
Repeated Mild Closed Head Injuries Induce Long-Term White Matter Pathology and Neuronal Loss That Are Correlated With Behavioral Deficits [0.03%]
重复轻度闭合性脑损伤诱导长期的白质病理改变和神经元丢失，并且与行为缺损相关
Eric M Gold,Vitaly Vasilevko,Jonathan Hasselmann et al.
Eric M Gold et al.
An estimated 5.3 million Americans are living with a disability from a traumatic brain injury (TBI). There is emerging evidence of the detrimental effects from repeated mild TBIs (rmTBIs). rmTBI manifests its own unique set of behavioral an...
T N Seyfried,H Choi,A Chevalier et al.
T N Seyfried et al.
Parkinson's disease (PD) is a neurodegenerative movement disorder involving the selective loss of dopamine-producing neurons in the substantia nigra (SN). Differences in disease presentation, prevalence, and age of onset have been reported ...
Multicenter Study
ASN neuro. 2018 Jan-Dec:10:1759091418781889. DOI:10.1177/1759091418781889 2018
Overexpression of CLEC18B Associates With the Proliferation, Migration, and Prognosis of Glioblastoma [0.03%]
CLEC18B过表达与胶质母细胞瘤的增殖、迁移和预后相关性研究
Rui-Ming Guo,Cheng-Bin Zhao,Peng Li et al.
Rui-Ming Guo et al.
C-type lectin domain family 18 member B (CLEC18B), encoding a superfamily of CLEC, has been found to be expressed in some of cancer cells, which possibly indicates it associated with cancer. However, the defined functional characterizations...
Neurotoxin-Induced Animal Models of Parkinson Disease: Pathogenic Mechanism and Assessment [0.03%]
神经毒素诱导的帕金森病动物模型：病理机制与评估方法
Xian-Si Zeng,Wen-Shuo Geng,Jin-Jing Jia
Xian-Si Zeng
Parkinson disease (PD) is the second most common neurodegenerative movement disorder. Pharmacological animal models are invaluable tools to study the pathological mechanisms of PD. Currently, invertebrate and vertebrate animal models have b...
In Vivo Optical Imaging of Myelination Events in a Myelin Basic Protein Promoter-Driven Luciferase Transgenic Mouse Model [0.03%]
基于髓鞘碱性蛋白启动子的荧光素酶转基因小鼠体内成像观察髓鞘形成事件
James Cao,Yanping Hu,Mohammed Salman Shazeeb et al.
James Cao et al.
The compact myelin sheath is important for axonal function, and its loss can lead to neuronal cell death and irreversible functional deficits. Myelin is vulnerable to a variety of metabolic, toxic, and autoimmune insults. In diseases like m...
Neuroprotective Role of Astroglia in Parkinson Disease by Reducing Oxidative Stress Through Dopamine-Induced Activation of Pentose-Phosphate Pathway [0.03%]
少突胶质细胞通过多巴胺诱导活化戊糖磷酸途径降低氧化应激来发挥帕金森病神经保护作用
Kyoko Mashima,Shinichi Takahashi,Kazushi Minami et al.
Kyoko Mashima et al.
Oxidative stress plays an important role in the onset and progression of Parkinson disease. Although released dopamine at the synaptic terminal is mostly reabsorbed by dopaminergic neurons, some dopamine is presumably taken up by astroglia....
Metabolic and Structural Imaging at 7 Tesla After Repetitive Mild Traumatic Brain Injury in Immature Rats [0.03%]
重复性轻度创伤性脑损伤后幼年 rats 的代谢和结构成像（7特斯拉）
Emin Fidan,Lesley M Foley,Lee Ann New et al.
Emin Fidan et al.
Mild traumatic brain injury (mTBI) in children is a common and serious public health problem. Traditional neuroimaging findings in children who sustain mTBI are often normal, putting them at risk for repeated mTBI (rmTBI). There is a need f...
Methylglyoxal Disrupts Paranodal Axoglial Junctions via Calpain Activation [0.03%]
甲基乙二醛通过激活钙蛋白酶破坏半节间体轴突胶质连接
Ryan B Griggs,Leonid M Yermakov,Domenica E Drouet et al.
Ryan B Griggs et al.
Nodes of Ranvier and associated paranodal and juxtaparanodal domains along myelinated axons are essential for normal function of the peripheral and central nervous systems. Disruption of these domains as well as increases in the reactive ca...
Corrigendum [0.03%]
勘误表
Lavezzi, A. M., Ferrero, S., Roncati, L., Piscioli, F., Matturri, L. & Pusiol, T. (2017). Nicotinic receptor abnormalities in the cerebellar cortex of sudden unexplained fetal and infant death victims-possible correlation with maternal smok...
Published Erratum
ASN neuro. 2018 Jan-Dec:10:1759091417752571. DOI:10.1177/1759091417752571 2018