Increased Behavioral Deficits and Inflammation in a Mouse Model of Co-Morbid Traumatic Brain Injury and Post-Traumatic Stress Disorder [0.03%]
共病创伤性脑损伤和创伤后应激障碍的小鼠模型中的行为缺损加重和炎症反应
Arman Fesharaki-Zadeh,Jeremy T Miyauchi,Karrah St Laurent-Arriot et al.
Arman Fesharaki-Zadeh et al.
Comorbid post-traumatic stress disorder with traumatic brain injury (TBI) produce more severe affective and cognitive deficits than PTSD or TBI alone. Both PTSD and TBI produce long-lasting neuroinflammation, which may be a key underlying m...
Melatonin Reduces GSK3β-Mediated Tau Phosphorylation, Enhances Nrf2 Nuclear Translocation and Anti-Inflammation [0.03%]
褪黑素通过降低GSK3β介导的Tau磷酸化、促进Nrf2核转位及抗炎作用减少阿尔茨海默病病理变化
Rashmi Das,Abhishek Ankur Balmik,Subashchandrabose Chinnathambi
Rashmi Das
Alzheimer's disease is a neuropathological condition with abnormal accumulation of extracellular Amyloid-β plaques and intracellular neurofibrillary tangles of Microtubule-associated protein Tau (Tau) in the brain. In pathological conditio...
Erratum to "Astrocyte-Selective Volume Increase in Elevated Extracellular Potassium Conditions Is Mediated by the Na+/K+ ATPase and Occurs Independently of Aquaporin 4" [0.03%]
“AQP4独立的、由Na+/K+ATP酶介导的升高细胞外钾条件下星形胶质细胞容积选择性增加”的勘误公告
Published Erratum
ASN neuro. 2020 Jan-Dec:12:1759091420983967. DOI:10.1177/1759091420983967 2020
Astrocyte Glutamate Uptake and Water Homeostasis Are Dysregulated in the Hippocampus of Multiple Sclerosis Patients With Seizures [0.03%]
多发性硬化症患者的海马星形胶质细胞谷氨酸摄取和水稳态失调
Andrew S Lapato,Sarah M Thompson,Karen Parra et al.
Andrew S Lapato et al.
While seizure disorders are more prevalent among multiple sclerosis (MS) patients than the population overall and prognosticate earlier death & disability, their etiology remains unclear. Translational data indicate perturbed expression of ...
Merits and Limitations of Studying Neuronal Depolarization-Dependent Processes Using Elevated External Potassium [0.03%]
使用 elevated external potassium研究神经元去极化依赖性过程的优势和局限性
Kira D A Rienecker,Robert G Poston,Ramendra N Saha
Kira D A Rienecker
Elevated extracellular potassium chloride is widely used to achieve membrane depolarization of cultured neurons. This technique has illuminated mechanisms of calcium influx through L-type voltage sensitive calcium channels, activity-regulat...
Cnp Promoter-Driven Sustained ERK1/2 Activation Increases B-Cell Activation and Suppresses Experimental Autoimmune Encephalomyelitis [0.03%]
B细胞活化和抑制实验性自身免疫性脑脊髓炎的CNP启动子驱动的持续ERK1 / 2活化
Marisa A Jeffries,Alison E Obr,Kelly Urbanek et al.
Marisa A Jeffries et al.
The ERK1/2 signaling pathway promotes myelin wrapping during development and remyelination, and sustained ERK1/2 activation in the oligodendrocyte (OL) lineage results in hypermyelination of the CNS. We therefore hypothesized that increased...
Norepinephrine Regulation of Adrenergic Receptor Expression, 5' AMP-Activated Protein Kinase Activity, and Glycogen Metabolism and Mass in Male Versus Female Hypothalamic Primary Astrocyte Cultures [0.03%]
去甲肾上腺素对雄激素和雌激素源性下丘脑原代星形胶质细胞培养中肾上腺受体表达、5' AMP活化蛋白激酶活性和糖原代谢及质量的调节作用
Mostafa M H Ibrahim,Khaggeswar Bheemanapally,Paul W Sylvester et al.
Mostafa M H Ibrahim et al.
Norepinephrine (NE) control of hypothalamic gluco-regulation involves astrocyte-derived energy fuel supply. In male rats, exogenous NE regulates astrocyte glycogen metabolic enzyme expression in vivo through 5'-AMP-activated protein kinase ...
Comparative Study
ASN neuro. 2020 Jan-Dec:12:1759091420974134. DOI:10.1177/1759091420974134 2020
Astrocyte-Selective Volume Increase in Elevated Extracellular Potassium Conditions Is Mediated by the Na+/K+ ATPase and Occurs Independently of Aquaporin 4 [0.03%]
高细胞外钾浓度条件下天冬细胞的选择性容积增加是由Na+/K+ATP酶介导并独立于水通道蛋白4发生的过程
Erin Walch,Thomas R Murphy,Nicholas Cuvelier et al.
Erin Walch et al.
Astrocytes and neurons have been shown to swell across a variety of different conditions, including increases in extracellular potassium concentration (^[K+]o). The mechanisms involved in the coupling of K+ influx to water movement into cel...
History of Neuroscience I. Pío del Río-Hortega (1882-1945): The Discoverer of Microglia and Oligodendroglia [0.03%]
神经科学历史伊.里奥-del-Rio Hortega（1882-1945）：发现小胶质细胞和少突胶质细胞的人
Anne I Boullerne,Douglas L Feinstein
Anne I Boullerne
Iron Metabolism in Oligodendrocytes and Astrocytes, Implications for Myelination and Remyelination [0.03%]
少突胶质细胞和星形胶质细胞中的铁代谢对髓鞘形成与再生的影响
Veronica T Cheli,J Correale,Pablo M Paez et al.
Veronica T Cheli et al.
Iron is a key nutrient for normal central nervous system (CNS) development and function; thus, iron deficiency as well as iron excess may result in harmful effects in the CNS. Oligodendrocytes and astrocytes are crucial players in brain iro...