Fernando Janczur Velloso,Sandhya Shankar,Vladimir Parpura et al.
Fernando Janczur Velloso et al.
At the turn of the 21st century studies of the cells that resided in the adult mammalian subventricular zone (SVZ) characterized the neural stem cells (NSCs) as a subtype of astrocyte. Over the ensuing years, numerous studies have further c...
Multitarget Activities of Müller Glial Cells and Low-Density Lipoprotein Receptor-Related Protein 1 in Proliferative Retinopathies [0.03%]
Müller胶质细胞和低密度脂蛋白受体相关蛋白1在增殖性视网膜病变中的多靶标活性
María C Sanchez,Gustavo A Chiabrando
María C Sanchez
Müller glial cells (MGCs), the main glial component of the retina, play an active role in retinal homeostasis during development and pathological processes. They strongly monitor retinal environment and, in response to retinal imbalance, a...
Estela M Muñoz
Estela M Muñoz
The circumventricular organs (CVOs) are unique areas within the central nervous system. They serve as a portal for the rest of the body and, as such, lack a blood-brain barrier. Microglia are the primary resident immune cells of the brain p...
Circadian Clock, Glucocorticoids and NF-κB Signaling in Neuroinflammation- Implicating Glucocorticoid Induced Leucine Zipper as a Molecular Link [0.03%]
生物钟、糖皮质激素和NF-κB信号在神经炎症中的作用——GLUCOCORTICOID INDUCED LEUCINE ZIPPER为分子联系点的一种可能
Mythily Srinivasan,Chandler Walker
Mythily Srinivasan
Inflammation including neuroinflammation is considered a protective response and is directed to repair, regenerate, and restore damaged tissues in the central nervous system. Persistent inflammation due to chronic stress, age related accrua...
New Target for Prevention and Treatment of Neuroinflammation: Microglia Iron Accumulation and Ferroptosis [0.03%]
神经炎症预防和治疗新靶点：小胶质细胞铁沉积与铁死亡
Shunfeng Liu,Xue Gao,Shouhong Zhou
Shunfeng Liu
Microglia play an important role in maintaining central nervous system homeostasis and are the major immune cells in the brain. In response to internal or external inflammatory stimuli, microglia are activated and release numerous inflammat...
Defibrinogenation Ameliorates Retinal Microgliosis and Inflammation in A CX3CR1-Independent Manner [0.03%]
纤溶原化以CX3CR1独立的方式减轻视网膜小胶质细胞激活和炎症反应
Borna Sarker,Sandra M Cardona,Kaira A Church et al.
Borna Sarker et al.
Diabetic human and murine retinas revealed pronounced microglial morphological activation and vascular abnormalities associated with inflammation. Pharmacological fibrinogen depletion using ancrod dampened microglial morphology alterations,...
Acute Manganese Exposure Modifies the Translation Machinery via PI3K/Akt Signaling in Glial Cells [0.03%]
急性锰暴露通过PI3K/Akt信号改变星形胶质细胞的翻译机器
Jzmín Soto-Verdugo,Janisse Siva-Parra,Luisa C Hernández-Kelly et al.
Jzmín Soto-Verdugo et al.
We demonstrate herein that short-term exposure of radial glia cells to Manganese, a neurotoxic metal, induces an effect on protein synthesis, altering the protein repertoire of these cells. ...
Multispectral LEDs Eliminate Lipofuscin-Associated Autofluorescence for Immunohistochemistry and CD44 Variant Detection by in Situ Hybridization in Aging Human, non-Human Primate, and Murine Brain [0.03%]
多光谱LED消除脂褐素相关自发荧光用于免疫组化和原位杂交检测老化人脑，非人灵长类动物脑和小鼠脑中的CD44变体
Philip A Adeniyi,Katie-Anne Fopiano,Fatima Banine et al.
Philip A Adeniyi et al.
A major limitation of mechanistic studies in aging brains is the lack of routine methods to robustly visualize and discriminate the cellular distribution of tissue antigens using fluorescent immunohistochemical multi-labeling techniques. Al...
Cuprizone-induced Demyelination in Mouse Brain is not due to Depletion of Copper [0.03%]
杯rizone诱导的小鼠脑脱髓鞘不是由于铜的耗尽所致
Megan L Morgan,Wulin Teo,Yda Hernandez et al.
Megan L Morgan et al.
The demyelinating effects of CPZ are not due to Cu deficiency but are instead consistent with acute toxicity of a CPZ + Cu complex. ...
Dopamine D2 and Adenosine A2A Receptors Interaction on Ca2+ Current Modulation in a Rodent Model of Parkinsonism [0.03%]
多巴胺D2和腺苷A2A受体在Parkinson病动物模型中对Ca2+电流的调节及它们之间的交互作用研究
Ernesto Alberto Rendón-Ochoa,Montserrat Padilla-Orozco,Vladimir Melesio Calderon et al.
Ernesto Alberto Rendón-Ochoa et al.
A2A receptor required previous D2 receptor activation to modulate Ca2+ currents. Istradefylline decreases pramipexole modulation on Ca2+ currents. Istradefylline reduces A2A + neurons activity in striatial microcircuit, but pramipexole fail...