In-vitro interaction studies between the amyloid PET tracer florbetaben and the amyloid-beta targeting antibodies lecanemab and donanemab on AD brain samples reveal no interferences [0.03%]
体外实验研究显示弗洛贝特班与仑卡奈单抗和多纳奈单抗在阿尔茨海默病脑样本上的相互作用不会产生干扰
Andre Mueller,Aleksandar Jovalekic,Marianne Chapleau et al.
Andre Mueller et al.
Background: Amyloid PET imaging enables the in vivo visualization and quantification of amyloid-beta deposits in the brain. In research and clinical settings, it is further used to monitor amyloid-beta burden as well as t...
Resource-stratified machine learning framework for cognitive status classification and mild cognitive impairment to dementia progression prediction [0.03%]
基于资源分层的机器学习框架在认知状态分类及轻度认知障碍至痴呆发展的预测中的应用
Jingmei Yang,Huitong Ding,Samad Amini et al.
Jingmei Yang et al.
Prevalence and clinical effects of Lewy Body pathology in non-prion rapidly progressive dementias: a retrospective cohort study [0.03%]
路易体病在非共济失调快速进行性痴呆中的流行率和临床影响:回顾性队列研究
Andrea Mastrangelo,Serena Caldera,Simone Baiardi et al.
Andrea Mastrangelo et al.
Evaluating the real-world performance of plasma pTau217 and pTau181 in a Southeast Asian tertiary memory clinic [0.03%]
评估血浆pTau217和pTau181在东南亚三级记忆诊所中的实际表现
Yi Jayne Tan,Raziyeh Mohammadi,Seyed Ehsan Saffari et al.
Yi Jayne Tan et al.
The active ingredients: physical activity features linked to healthy brain aging [0.03%]
活跃的成分:与健康大脑老化相关的身体活动特征
Claire J Cadwallader,Pedro Pinheiro-Chagas,Rowan Saloner et al.
Claire J Cadwallader et al.
α-synuclein positivity is associated with decline in brain microstructure in the Alzheimer's disease spectrum [0.03%]
阿尔茨海默病谱系中α-突触核蛋白阳性和脑微结构变化的关系
Elijah Mak,Scott A Przybelski,Robert I Reid et al.
Elijah Mak et al.
YIAD-0501 directly dissociates aggregates of full-length and N-terminal pyroglutamate-modified forms of Aβ [0.03%]
YIAD-0501直接分解全长和N端吡咯烷修饰形式的Aβ聚集物
Heewon Shin,Sunhee Lee,Wonbin Seo et al.
Heewon Shin et al.
Prospective study on clinical utility of plasma p-Tau217 and other biomarkers in Japanese memory clinics using the LUMIPULSE platform [0.03%]
日本记忆门诊中LUMIPULSE平台的血浆p-Tau217和其他生物标志物临床效用的前瞻性研究
Takanobu Ishiguro,Masanori Kurihara,Yoichiro Nishida et al.
Takanobu Ishiguro et al.
Automated high-throughput quantification of plasma p-tau217 and APOE-ε4 for Alzheimer's disease diagnosis and cognitive decline in a memory cohort [0.03%]
基于记忆队列的阿尔茨海默病诊断和认知衰退的血浆p-tau217和APOE-ε4自动化高通量量化
Jochen Titeca,Marta Scarioni,Matthijs Oyaert et al.
Jochen Titeca et al.
Background: Blood-based biomarkers could improve the precision of Alzheimer's disease (AD) clinical diagnosis and expand access to targeted treatments. Therefore, we evaluated the diagnostic accuracy of plasma Elecsys p-t...
Nelsan Pourhadi,Christina Jensen-Dahm,Thomas Munk Laursen et al.
Nelsan Pourhadi et al.