Weak Social Networks in Late Life Predict Incident Alzheimer's Disease: The Kuakini Honolulu-Asia Aging Study [0.03%]
社交薄弱与阿尔茨海默病的发病风险关系——库阿基尼 Honolulu-Asia 老龄化研究
Kalpana J Kallianpur,Kamal H Masaki,Randi Chen et al.
Kalpana J Kallianpur et al.
Background: We assessed 10-year longitudinal associations between late-life social networks and incidence of all-cause dementia (ACD), Alzheimer's disease (AD), and vascular dementia (VaD) in Japanese-American men. ...
Investigating Biological Pathways Underpinning the Longitudinal Association Between Loneliness and Cognitive Impairment [0.03%]
探究孤独与认知障碍纵向关联的生物学途径
Kexin Yu,Ted Kheng Siang Ng
Kexin Yu
Background: Loneliness precedes the onset of cognitive impairment (CI) in older adults. Although the mechanisms through which loneliness "gets under the skin" to influence the risk of developing CI have been conceptually ...
Potential Solutions for the Mitigation of Hip Injuries Caused by Falls in Older Adults: A Narrative Review [0.03%]
老年人跌倒所致髋部损伤的预防方法：综述性研究
Rebecca J Tarbert,Junhong Zhou,Brad Manor
Rebecca J Tarbert
Background: Hip injuries caused by falling are common and often catastrophic for older adults. There is thus an urgent need to develop solutions designed to mitigate fall injuries to the hip by reducing the forces created...
Trends in Frailty Between 1990 and 2020 in Sweden Among 75-, 85-, and 95-Year-Old Women and Men: A Nationwide Study from Sweden [0.03%]
瑞典1990至2020年75、85和95岁男女虚弱症变化的全国性研究
Alexandra M Wennberg,Marcus Ebeling,Stina Ek et al.
Alexandra M Wennberg et al.
Background: Aging is the primary risk factor for frailty, which is defined as an inability to respond to acute or chronic stressors. Individuals are living longer with greater multimorbidity, but there is a paucity of evi...
Regional Neuroanatomic Effects on Brain Age Inferred Using Magnetic Resonance Imaging and Ridge Regression [0.03%]
基于磁共振影像的岭回归推断脑表型年龄的区域神经解剖效应
Roy J Massett,Alexander S Maher,Phoebe E Imms et al.
Roy J Massett et al.
The biological age of the brain differs from its chronological age (CA) and can be used as biomarker of neural/cognitive disease processes and as predictor of mortality. Brain age (BA) is often estimated from magnetic resonance images (MRIs...
Medication Regimen Complexity and Risk of Bleeding in People Who Initiate Oral Anticoagulants for Atrial Fibrillation: A Population-Based Study [0.03%]
口服抗凝药治疗房颤患者的用药复杂性及其出血风险：基于人群的队列研究
Esa Y H Chen,Jiaxi Zhao,Jenni Ilomäki et al.
Esa Y H Chen et al.
Background: Oral anticoagulants (OACs) are high-risk medications often used in older people with complex medication regimens. This study was the first to assess the association between overall regimen complexity and bleed...
The Role of Physical Activity on the Relationships Between Pain, Anxiety, and Sleep Quality in Older Age [0.03%]
身体活动在疼痛、焦虑和睡眠质量之间的关系中的作用：一项针对老年人的研究
Julia L Sheffler,Hollyn Saliga,Scott Pickett
Julia L Sheffler
Background: Sleep quality is associated with a range of negative outcomes in older adults, including a higher risk for cognitive decline, greater disability, and poorer quality of life. Pain and anxiety are both important...
Associations of 24-Hour Light Exposure and Activity Patterns and Risk of Cognitive Impairment and Decline in Older Men: The MrOS Sleep Study [0.03%]
24小时光照暴露和活动模式与老年男性认知障碍和衰退风险的相关性：MrOS睡眠研究
Terri L Blackwell,Mariana G Figueiro,Gregory J Tranah et al.
Terri L Blackwell et al.
Background: Older men with the worse alignment of activity and light may have lower levels of cognition and increased rates of cognitive decline. Methods:...
The Associations of Individual and Subclasses of Nonesterified Fatty Acids With Disability, and Mobility Limitation in Older Adults: The Cardiovascular Health Study [0.03%]
循环未酯化脂肪酸与老年人的行动能力及功能障碍的关系：心血管健康研究项目的证据
Peter D Ahiawodzi,Petra Buzkova,Alice H Lichtenstein et al.
Peter D Ahiawodzi et al.
Background: We sought to determine the associations between individual nonesterified fatty acids (NEFAs) and disability and mobility limitation. Methods: ...
Musculoskeletal Pain, a Possible Indicator of Central Sensitization, Is Positively Associated With Lower Urinary Tract Symptom Progression in Community-Dwelling Older Men [0.03%]
肌肉骨骼疼痛可能是中枢敏化的一种指标，与社区居住老年男性下尿路症状进展正相关
Angela Senders,Scott R Bauer,Yiyi Chen et al.
Angela Senders et al.
Background: Musculoskeletal pain, a possible marker of central sensitization, is associated with higher prevalence of lower urinary tract symptoms (LUTS) among older men. We investigated whether musculoskeletal pain is as...