Transitions Between Mild Cognitive Impairment, Dementia, and Mortality: The Importance of Olfaction [0.03%]
轻度认知障碍,痴呆和死亡之间的转变:嗅觉的重要性
Jamie E Knight,Tomiko Yoneda,Nathan A Lewis et al.
Jamie E Knight et al.
Background: The existing literature suggests that impaired olfaction may be an early marker for cognitive decline. Tracking the earliest stages of the progression to dementia is paramount, and yet the importance of olfact...
Association Between Pain and Sarcopenia Among Adults Aged ≥65 Years from Low- and Middle-Income Countries [0.03%]
疼痛与中低收入国家65岁以上成人肌少症的关联研究
Lee Smith,Guillermo F López Sánchez,Nicola Veronese et al.
Lee Smith et al.
Background: Pain may increase the risk for sarcopenia, but existing literature is only from high-income countries, while the mediators of this association are largely unknown. Thus, we aimed to investigate the association...
Validation of Self-Reported Cancer Diagnoses by Respondent Cognitive Status in the U.S. Health and Retirement Study [0.03%]
通过受访者认知状态验证美国卫生退休研究中的自报癌症诊断结果
Megan A Mullins,Mohammed Kabeto,Lauren P Wallner et al.
Megan A Mullins et al.
Background: Cancer and dementia are becoming increasingly common co-occurring conditions among older adults. Yet, the influence of participant cognitive status on the validity of self-reported data among older adults in p...
Metabolomics-Based Identification of Metabolic Dysfunction in Frailty [0.03%]
基于代谢组学的脆弱状态下的代谢功能紊乱的识别
Reyhan Westbrook,Cissy Zhang,Huanle Yang et al.
Reyhan Westbrook et al.
Dysregulation of energy producing metabolic pathways has been observed in older adults with frailty. In this study, we used liquid chromatography-mass spectrometry technology to identify aging- and frailty-related differences in metabolites...
Development of Prognostic Prediction Model to Estimate Mortality for Frail Oldest Old: Prospective Cohort Study [0.03%]
为衰弱的高龄老人估计死亡率的预后预测模型的开发:前瞻性队列研究
Yaohua Gu,Wenwen Wu,Chan Kong et al.
Yaohua Gu et al.
Background: This study was performed to derive and validate a prognostic prediction model for individualized estimation of mortality risk among the frail oldest old (aged 80 years or older). ...
Linear and Nonlinear Associations Between Vitamin D and Grip Strength: A Mendelian Randomization Study in UK Biobank [0.03%]
维生素D与握力之间的线性及非线性关联:英国生物样本库中的孟德尔随机化研究
Snehal M Pinto Pereira,Victoria Garfield,Thomas Norris et al.
Snehal M Pinto Pereira et al.
Background: Low vitamin D status is a widespread phenomenon. Similarly, muscle weakness, often indicated by low grip strength, is another public health concern; however, the vitamin D-grip strength relationship is equivoc...
Appendicular Lean Mass, Grip Strength, and the Incidence of Dementia Among Older Adults in the Health ABC Study [0.03%]
附肢瘦体重,握力和老年人痴呆症的发生率在健康ABC研究中的关系
James S Andrews,Laura S Gold,May J Reed et al.
James S Andrews et al.
Background: Identification of novel risk factors for dementia in older adults could facilitate development of methods to identify patients most at risk and improve their cognitive outcomes. We aimed to determine whether l...
Impact of Pneumonia on Cognitive Aging: A Longitudinal Propensity-Matched Cohort Study [0.03%]
肺炎对认知衰老的影响:一项纵向倾向匹配队列研究
Merle K Hendel,Debora Rizzuto,Giulia Grande et al.
Merle K Hendel et al.
Background: Acute clinical events, such as pneumonia, may impact physical functionality but their effect on cognition and the possible duration of this effect remains to be quantified. This study investigated the impact o...
Association Between Alcohol Use Disorders and Dementia in 262,703 Dementia-free Finnish Adults: Is Cardiovascular Disease a Mediator? [0.03%]
262703名无痴呆症的芬兰成年人中酒精使用障碍与痴呆之间的联系:心血管疾病是中介吗?
Yaoyue Hu,Kaarina Korhonen,Peng Li et al.
Yaoyue Hu et al.
Background: The possible mediating role of cardiovascular disease (CVD) in the relationship between alcohol use disorders (AUD) and the risk of early-onset (
Peak Expiratory Flow Predicts Incident Dementia in a Representative Sample of U.S. Older Adults: The National Health and Aging Trends Study (NHATS) [0.03%]
峰值呼气流速可预测美国老年人群中新发痴呆的发生:全国健康和老龄化趋势研究(NHATS)
Patrick T Donahue,Qian-Li Xue,Michelle C Carlson
Patrick T Donahue
Background: Dementia is an increasingly important public health problem with various risk factors. Respiratory function, measured via peak expiratory flow (PEF), may be a modifiable dementia risk factor. ...