Development and Evaluation of a Cross-Study Comparable Frailty Index based on Item Response Theory: Insights from Three Prospective Cohorts [0.03%]
基于项目反应理论的跨研究可比脆弱性指数的开发与评估：来自三项前瞻性队列研究的启示
Shuai Liu,Guangquan Ran,Yan Wang et al.
Shuai Liu et al.
Background: The Frailty Index of Accumulative Deficits (FI-CD) is a key predictor of adverse health outcomes in older adults, but its utility for cross-study comparisons is limited due to assumptions of item homogeneity. ...
Sex Differences in Genetic Modifiers of Traumatic Brain Injury and Late-Life Cognitive Decline: The Cache County Study [0.03%]
性别差异影响创伤性脑损伤和晚年认知衰退的遗传修饰因子——来自Cache County研究的证据
Mikaela A Drewel,Sarah Schwartz,Gail B Rattinger et al.
Mikaela A Drewel et al.
Traumatic brain injury (TBI) is a well-recognized risk factor for late-life cognitive decline. However, few studies have examined individual differences in sex and genetics, which may modify risk. We examined sex differences in gene-TBI int...
Association between metabolic heterogeneity of obesity and the progression of muscle strength decline: a prospective cohort study [0.03%]
肥胖代谢异质性与肌肉力量下降进展关联的前瞻性队列研究
Zhenzhen Liang,Wei Jin,Sheng Liu et al.
Zhenzhen Liang et al.
Background: Obesity exhibits metabolic heterogeneity, but its impact on muscle strength decline remains unclear. Methods: Based on 7,77...
Bone Health and Body Composition in Pre-Frail and Frail Older Adult Women: Insights from High-Resolution Peripheral Quantitative Computed Tomography (HR-pQCT) [0.03%]
高分辨率外周定量计算机断层扫描（HR-pQCT）对前衰弱和衰弱老年女性骨健康和体成分的见解
Alan L Fernandes,Diogo S Domiciano,Valeria F Caparbo et al.
Alan L Fernandes et al.
Background: Age-related muscle decline and obesity are associated with impaired bone health and substantially increased fragility and fracture risk; however, evidence in frail populations remains inconsistent. We investig...
The association of cataract surgery with risk of falls and fractures among medicare enrollees with cataract [0.03%]
白内障患者行白内障手术与摔倒和骨折风险的关联性研究
Atalie C Thompson,Lindsey I Abdelfattah,Emilie D Duchesneau et al.
Atalie C Thompson et al.
Background: Falls and fractures are a significant public health concern linked to visual impairment. Cataracts are the most common cause of visual impairment in older adults and can be corrected with cataract surgery. Thi...
Young plasma transfer enhances antioxidant defense and preserves structural integrity in aged lung tissue [0.03%]
年轻血浆的转移可以增强抗氧化防御并保持衰老肺组织的结构完整性
Özlem Düvenci Birben,Hikmet Taner Teker,Seda Keskin et al.
Özlem Düvenci Birben et al.
The present study investigated the impact of heterochronic plasma exchange between young and aged rats on oxidative stress, antioxidant defense, inflammation, and lung histology. Twenty-four-month-old male Sprague-Dawley rats received 0.5 m...
Ambient Air Pollution, Greenness and Frailty in an Elder Asian Population: A Multi-Center Study with Long-Term Exposure [0.03%]
空气污染、绿化与老年亚洲人群的衰弱：一项长期暴露的多中心研究
Ping Shih,Shu-Chun Chuang,Chao Agnes Hsiung et al.
Ping Shih et al.
Background: Long-term exposure to air pollution has been linked to adverse health outcomes in older adults; however, its association with frailty, particularly the potential protective role of environmental factors such a...
Association between shingles vaccination and slower biological aging: Evidence from a U.S. population-based cohort study [0.03%]
带状疱疹疫苗与生物衰老减缓的关联：一项基于美国人群队列研究的证据
Jung Ki Kim,Eileen M Crimmins
Jung Ki Kim
There is growing interest in whether adult vaccines such as shingles vaccine may slow biological aging beyond preventing acute infections. Using data from the nationally representative U.S. Health and Retirement Study, we examined whether s...
Digital markers and phenotypes of rest-activity rhythms in people with advanced dementia using real-time location data [0.03%]
基于实时定位数据的痴呆患者休息活动规律的数字标志物与表型研究
Yasser Karam,Leia C Shum,Tamim Faruk et al.
Yasser Karam et al.
Background: Disrupted sleep and circadian rhythms in dementia affect rest-activity patterns and impact quality of life, safety, and caregiver burden. The objective of this study is to extend the application of real-time l...
The bidirectional relationship between diabetes and poor muscle function in older adults: data from two population-based studies [0.03%]
老年人糖尿病与肌肉功能不良的双向关系：两项基于人群的研究数据
Caterina Trevisan,Francesca Remelli,Stefania Bandinelli et al.
Caterina Trevisan et al.
Background: Skeletal muscle dysfunction contributes significantly to disability, which is one of the most common complications of diabetes in older adults. We aimed to assess whether diabetes was associated with a steeper...