Obesity and healthy aging: fat, muscle, and bone trade-offs in an era of potent weight-loss pharmacotherapy [0.03%]
肥胖与健康老龄化：减肥药物时代下的脂肪、肌肉和骨骼的权衡取舍问题
Samrah Siddiqui,Vafa Tabatabaie,Sandra Aleksic
Samrah Siddiqui
Intrinsic capacity and healthy ageing in the United Kingdom and Brazil: a coordinated analysis of two population-based cohort studies [0.03%]
英国和巴西的内在能力与健康老龄化：两项基于人群队列研究的综合分析
Laiss Bertola,Yu-Tzu Wu,Márlon Juliano Romero Aliberti et al.
Laiss Bertola et al.
Background: Although intrinsic capacity (IC) is a multidimensional marker of healthy ageing, cross-country validation in diverse cultural and socioeconomic contexts remains limited. Our study aimed to harmonise the operat...
Associations of physical frailty with risk of incident cardiovascular disease by mediation of plasma metabolome changes [0.03%]
基于血浆代谢组改变的心肺疾病与机体虚弱的关联性研究
Guangbin Sun,Lan Yu,Nayili Mahemuti et al.
Guangbin Sun et al.
Background: Frailty has been increasingly recognized as a significant contributor to adverse cardiovascular outcomes. However, the metabolic mechanisms underlying this relationship remain unclear. This study aimed to iden...
Social and clinical frailty indices in aging mice: A comparative analysis of longitudinal and cross-sectional designs [0.03%]
纵向和横断设计的小鼠社交和临床脆弱性指数的比较分析
Maria Razzoli,Charles W Collinge,Monica Luciana et al.
Maria Razzoli et al.
Aging is a heterogeneous phenomenon provoked by biological processes that still need to be fully understood. Frailty is a relevant outcome of aging reflecting biological decline that can be quantified through indices measuring the accumulat...
Moving Geroscience Forward in China: Proceedings of the First International Exchange Forum of the Chinese Geriatrics Society [0.03%]
中国健康老龄化之路——中华医学会老年医学分会国际学术论坛论文集
Le Zhang,Tianyi Ji,Jianghan Bi et al.
Le Zhang et al.
Held on 17 August 2025 in Guangzhou, the inaugural International Exchange Forum of the Chinese Geriatrics Society marked a significant milestone in advancing geroscience and fostering global collaboration in China. The forum brought togethe...
Associations of common infections with frailty and mortality in two UK cohort studies [0.03%]
英国两项前瞻性队列研究中普通感染与衰弱和死亡率的关联性研究
Demelza Smeeth,Charlotte Warren-Gash,Rebecca E Green et al.
Demelza Smeeth et al.
Background: Some common infections are associated with poorer age-related health outcomes; however, findings are limited to a small number of pathogens and frequently inconclusive. This study aimed to expand the range of ...
Revisiting socioeconomic disadvantage estimates in the National Health and Aging Trends Study [0.03%]
重新审视国家健康和老龄化趋势研究中的经济社会劣势估计值
Vicki A Freedman,Jennifer A Schrack
Vicki A Freedman
Benchmarking Weighted Estimates of Social Determinants of Health in the National Health and Aging Trends Study (NHATS) [0.03%]
国家健康和老龄化趋势研究(NHATS)中加权估计的社会健康决定因素的基准测试
Thomas M Gill,Linda Leo-Summers,Jingchen Liang et al.
Thomas M Gill et al.
Bidirectional Associations Between Physical Function and Physical Activity Among Older Adults Living with Dementia [0.03%]
痴呆老人身体功能与身体活动的双向关联
Shijun Zhu,Barbara Resnick,Marie Boltz et al.
Shijun Zhu et al.
Background: Previous research has suggested a likely reciprocal relationship between physical function and physical activity among older adults, but few assessed those living with dementia. This study examined the bidirec...
Striatal Dopamine and Skeletal Muscle Energy Metabolism in Older Adults [0.03%]
老年人纹状体多巴胺与骨骼肌能量代谢的关系
Caterina Rosano,Nico I Bohnen,Brian Lopresti et al.
Caterina Rosano et al.
Background: Dopamine (DA) in the central nervous system is considered a master regulator of mobility performance and vigor, but its mechanistic relationship with skeletal muscle energetics is unclear. ...