Proceedings of the Alzheimer's Diagnosis in Older Adults with Chronic Conditions (ADACC) Network Inaugural Annual Conference [0.03%]
《老年人慢性疾病阿尔茨海默病诊断网络首届年会（ADACC）论文集》
Michelle M Mielke,Nicole R Fowler,Heather E Whitson et al.
Michelle M Mielke et al.
The Alzheimer's Disease in Older Adults with Chronic Conditions (ADACC) Network is funded by the National Institute on Aging as a U24 cooperative agreement. ADACC is an inclusive, multidisciplinary group across multiple institutions that is...
Discussing the interplay of social determinants of health, aging and Alzheimer's biomarkers in U.S. Latinos [0.03%]
讨论美国拉丁裔健康的社会决定因素、老龄化和阿尔茨海默病生物标志物之间的相互作用
Jairo E Martinez,Jaime Perales-Puchalt,Miriam J Rodriguez et al.
Jairo E Martinez et al.
This perspective examines the impact of Social Determinants of Health (SDoH) on biological age-related decline and Alzheimer's Disease and Related Dementias (ADRD) biomarker trajectories in U.S. Latino populations, emphasizing the need for ...
Workshop Report-Heterogeneity and Successful Aging Part I: Heterogeneity in Aging-Challenges and Opportunities [0.03%]
工作坊报告-老龄化异质性与成功老龄化第一部分：老龄化中的异质性-挑战与机遇
George A Kuchel,Andrea L Hevener,J Graham Ruby et al.
George A Kuchel et al.
Historically, aging research has focused primarily on the study of differences in means of varied measures obtained at different ages. However, growing evidence has shown that for many parameters, variability in measurements obtained both b...
Frailty mediated the associations of fine particulate matter with depression and anxiety: Findings from the UK Biobank [0.03%]
脆弱性介导了细颗粒物与抑郁和焦虑的关联：来自英国生物库的研究发现
Xiangying Suo,Junxi Zhang,Jing Guo et al.
Xiangying Suo et al.
Background: The role of frailty in the associations of fine particulate matter (PM2.5) with depression and anxiety was unknown. Methods: ...
Using computational video analysis in ageing mice to evaluate the effects of chronic monotherapy, polypharmacy and deprescribing over time [0.03%]
利用计算视频分析来评估老年小鼠长期单药治疗、多药共用和停药的影响变化
Kenji Fujita,John Mach,Sarah N Hilmer
Kenji Fujita
Background: In clinical studies of older adults, polypharmacy (use of ≥ 5 drugs) and the Drug Burden Index (DBI; measures exposure to anticholinergic and sedative drugs) are associated with impaired physical function and...
Upregulation of COX-2 and NADPH oxidase and reduced eNOS in perivascular adipose tissue are associated with resistance artery dysfunction and hypertension in naturally aged mice [0.03%]
COX-2和NADPH氧化酶上调以及老年小鼠 peri血管脂肪组织中eNOS减少与阻力动脉功能障碍和高血压有关
Grazielle Caroline da Silva,Maisa Nascimento Soares Amaral,Diogo Barros Peruchetti et al.
Grazielle Caroline da Silva et al.
Aging is a major risk factor for cardiovascular disease, with hypertension being the most common outcome. Hypertension often stems from resistance arteries endothelial dysfunction. Recent research highlights the pivotal role of perivascular...
A Preliminary Usability Evaluation of an Artificial Intelligence-based, motion-detecting Wearable device: the Geriatric Functional Assessment System [0.03%]
基于人工智能的运动检测可穿戴设备的初步可用性评估：老年功能评估系统
John A Batsis,Rishank Singh,Jennifer Poole et al.
John A Batsis et al.
Background: Physical function is a key determinant of independence among older adults. Yet, there are barriers to assessing physical function in clinic. We developed a wearable geriatric functional assessment system (GFAS...
Feasibility and Acceptability of a Technology Mediated Fall Risk Prevention Intervention for Older Adults with Mild Cognitive Impairment [0.03%]
用于轻度认知障碍老年人跌倒风险预防干预的技术介导的可行性与可接受性研究
George Demiris,Sean Harrison,Justine Sefcik et al.
George Demiris et al.
Background: Falls and fall-related injuries are significant public health issues for adults 65 years of age and older. The annual direct medical costs in the US as a result of falls are estimated to exceed $50 billion, an...
Impact of Potentially Inappropriate Medication on Disability and Mortality in Older Adults: Nationwide Population-Based Study in Korea [0.03%]
不适当用药对老年人残疾和死亡率的影响：韩国的全国性人群研究
Hee-Won Jung,So Jin Park,Hoyol Jhang et al.
Hee-Won Jung et al.
Background: Potentially Inappropriate Medications (PIMs) increase the risk of adverse health outcomes in older adults. However, the long-term effects of PIMs, particularly considering frailty and polypharmacy, remain uncl...
Are Maximal Power and Maximal Aerobic Capacity in Older and Very Old Adults Dependent on their Level of Physical Activity? [0.03%]
老年人和高龄老人的最大功率和最大摄氧量是否取决于他们的身体活动水平？
E Luneau,V Rozand,G Y Millet
E Luneau
Age-related declines in maximal power (Pmax) and maximal aerobic power (VO2max) impact functional capacities. Physical activity (PA) can mitigate their decline. The present study aimed to investigate the effects of age and habitual PA level...