Bidirectional Associations Between Physical Function and Physical Activity Among Older Adults Living with Dementia [0.03%]
痴呆老人身体功能与身体活动的双向关联
Shijun Zhu,Barbara Resnick,Marie Boltz et al.
Shijun Zhu et al.
Background: Previous research has suggested a likely reciprocal relationship between physical function and physical activity among older adults, but few assessed those living with dementia. This study examined the bidirec...
Striatal Dopamine and Skeletal Muscle Energy Metabolism in Older Adults [0.03%]
老年人纹状体多巴胺与骨骼肌能量代谢的关系
Caterina Rosano,Nico I Bohnen,Brian Lopresti et al.
Caterina Rosano et al.
Background: Dopamine (DA) in the central nervous system is considered a master regulator of mobility performance and vigor, but its mechanistic relationship with skeletal muscle energetics is unclear. ...
Development and Validation of Cardiorespiratory Fitness Prediction Equations from 6-Minute Walk Test in the CARDIA Study [0.03%]
基于CARDIA研究的六分钟步行试验心肺适能预测方程的建立和验证
Bjoern Hornikel,Erin E Dooley,C Barrett Bowling et al.
Bjoern Hornikel et al.
Background: Assessing maximal oxygen consumption (VO2max), the gold standard for assessing cardiorespiratory fitness (CRF), is often impractical in large-scale studies. We derived sex-specific VO2max and graded exercise t...
Biomarkers help us understand how cellular and systemic aging contribute to mortality: A study utilizing a machine learning approach in the Health and Retirement Study [0.03%]
生物标志物有助于我们了解细胞和系统衰老如何影响死亡率：利用机器学习方法在健康与退休研究中的应用研究报告
Eric T Klopack,Eileen M Crimmins
Eric T Klopack
Background: Research suggests aging is a coordinated physiological decline occurring in multiple systems and at multiple biological levels. However, it is largely unknown how general biological aging and specific systemic...
Benefits of Oral Nitrite Supplementation on Mitochondrial Respiration and Physical Function In Older Adults [0.03%]
口服一氧化氮前体补充剂对老年人线粒体呼吸和物理功能的益处
Daniel E Forman,Subashan Perera,Sruti Shiva et al.
Daniel E Forman et al.
Background: Age-associated decline in mitochondrial oxidative capacity is associated with increased risk of disease, frailty, and disability. Oral nitrite and nitrate supplementation have been demonstrated to improve mito...
Associations of unmet dental care needs due to cost with incident cardiovascular disease and dementia: a prospective study in the All of Us cohort [0.03%]
基于成本的未满足牙科护理需求与心血管疾病和痴呆症发病率之间的前瞻性研究：来自“全民参与”队列的数据分析
Mabeline Velez,Peter T Buto,Anna M Pederson et al.
Mabeline Velez et al.
Background: Poor oral health among older adults may contribute to cardiovascular and dementia risk via systemic inflammation and cardiometabolic comorbidities. Financial constraints are a major driver of unmet dental care...
Are Aging Clocks Based on Routine Clinical Indicators Trustworthy and Applicable? A Systematic Review and Critical Appraisal [0.03%]
基于常规临床指标的老化时钟可靠且适用吗？系统评价和批判性评估
Jiajia Zhang,Jie Hu,Yinyan Gao et al.
Jiajia Zhang et al.
Aging clocks based on routine clinical indicators have emerged as a cost-effective tool for assessing biological age. This systematic review aims to summarize the characteristics and critically appraise these available aging clocks. Studies...
The relative effects of different exercise modes on physical and metabolic health in older adults: A network meta-analysis [0.03%]
不同运动模式对老年人身心代谢健康影响的网络meta分析
Yuan Jiuchen,Fanghui L I,Shusheng Shi et al.
Yuan Jiuchen et al.
Background: Multiple exercise modalities are recommended for older adults, yet their comparative effectiveness remains uncertain. We conducted a Bayesian network meta-analysis of randomized trials to compare common exerci...
Socioeconomic and clinical predictors of all-cause mortality among older adults in India from 2017-2024: the importance of cognitive health and dementia [0.03%]
印度2017-2024年老年人全因死亡率的社会经济和临床预测因素：认知健康和痴呆的重要性
Emma Nichols,Sharmistha Dey,Pranali Khobragade et al.
Emma Nichols et al.
Background: Characterizing the correlates of adult mortality can lend insights into the factors associated with consequential health outcomes among older adults. In India, the importance of adult mortality has grown given...
Particulate Air Pollution and Post-Discharge Recovery Among Older Adults Hospitalized for Heart Failure in the United States [0.03%]
美国老年人因心力衰竭住院后的出院恢复与颗粒物空气污染的关系
Tong Wen,Jingwen Hu,Michelle Shardell et al.
Tong Wen et al.
Background: The impact of exposure to fine particulate matter (PM2.5) on post-discharge recovery in older adults already hospitalized for heart failure remains unclear. We evaluated associations between exposure to PM2.5 ...