The Association of Circulating Immune Cells with Cognitive Function, Brain Imaging, and Incident all-cause and Alzheimer's Dementia: The Framingham Offspring Study [0.03%]
循环免疫细胞与认知功能、脑影像以及全因和阿尔茨海默病痴呆发生率之间的关联：弗明汉后代研究
Yumeng Cao,Lindsay R Salvati,Jiachen Chen et al.
Yumeng Cao et al.
Background: Emerging evidence supports the central role of the immune system in brain health, yet little is known about the role of circulating immune cells and cognitive function or brain health in dementia-free populati...
ABCB1 Gene Polymorphisms and Their Contribution to Cognitive Decline in Mild Cognitive Impairment: A Next-Generation Sequencing Study [0.03%]
ABCB1基因多态性与轻度认知障碍患者认知下降的关系：一项基于下一代测序技术的研究
Omar Šerý,Kateřina Sheardová,Radka Dziedzinska et al.
Omar Šerý et al.
The ABCB1 gene, encoding the ATP-dependent translocase ABCB1, plays a crucial role in the clearance of amyloid-beta (Aβ) peptides and the transport of cholesterol, implicating it in the pathogenesis of Alzheimer's disease. The study aims t...
Severe cognitive decline in long-term care is related to gut microbiome production of metabolites involved in neurotransmission, immunomodulation, and autophagy [0.03%]
长期护理中严重认知衰退与肠道微生物群产生有关的代谢物，这些代谢物参与神经传导、免疫调节和自噬过程。
为了更符合中文标题的习惯，可以简化为：
长期护理中的严重认知衰退与肠道菌群产生的关键代谢物相关
Andrew P Shoubridge,Lucy Carpenter,Erin Flynn et al.
Andrew P Shoubridge et al.
Ageing-associated cognitive decline affects more than half of those in long-term residential aged care. Emerging evidence suggests that gut microbiome-host interactions influence the effects of modifiable risk factors. We investigated the r...
Ethics from the Outset: Incorporating Ethical Considerations into the AI Tech Collaboratories' Pilot Projects [0.03%]
从源头考虑伦理：在AI科技协作实验室的试点项目中融入伦理考量
Emily A Largent,Yungjee Kim,Jason Karlawish et al.
Emily A Largent et al.
There is an urgent need to develop tools enabling older adults to live healthy, independent lives as long as possible. To address this need, the National Institute on Aging (NIA) Artificial Intelligence and Technology Collaboratories (AITC)...
Metabolomic Pathways of Inflammation and Mitochondrial Dysfunction are Related to Worsening Healthy Aging Index and Mortality [0.03%]
与健康老化指数和死亡率变差相关的炎性和线粒体功能障碍的代谢通路
Shanshan Yao,Megan M Marron,Qu Tian et al.
Shanshan Yao et al.
Background: Metabolic-inflammatory states are central to multiorgan mechanisms of aging, but precise functional biomarkers of physiological aging remain less clear. ...
Relationship of multiple sensory impairments with physical performance in older adults in the Study of Muscle, Mobility and Aging [0.03%]
多种感官损伤与老龄化肌肉，移动和衰老研究中老年人身体机能的关系
Atalie C Thompson,Tyler Mansfield,Eileen Johnson et al.
Atalie C Thompson et al.
Background: Sensory and cognitive function can impact physical performance, but the relationship of multiple sensory impairments (SI) with mobility in older adults is not well understood. We hypothesized that severity and...
It's never too early, it's never too late: the potential of health behaviours for cardiovascular health in nonagenarians. Data from the Mugello Study [0.03%]
为时未晚，也为时未迟：健康行为对九十多岁老人心血管健康的潜力。穆杰洛研究的数据
Silvia Pancani,Gemma Lombardi,Francesco Sofi et al.
Silvia Pancani et al.
Background: The Life's Essential 8 (LE8) is a composite metric including four health behaviours (diet, physical activity, nicotine exposure, and sleep) and four health factors (body mass index, non-high density lipoprotei...
Mito-Modulatory Medication Use and Skeletal Muscle Bioenergetics Among Older Men and Women: the Study of Muscle, Mobility and Aging [0.03%]
老年男性和女性的线粒体调控药物使用和骨骼肌生物能量学研究：肌肉，移动性和老化研究
Howard J Phang,Jaclyn Bergstrom,Rabia S Atayee et al.
Howard J Phang et al.
Background: The potential impacts of drug-induced modulation of mitochondrial function in humans remain unclear despite the high prevalence of "mito-modulatory" medication use among older adults. While these medications, ...
Longitudinal association between multimorbidity, participating activity and cognitive function: cross-lagged mediation analysis [0.03%]
多病共存、参与活动和认知功能之间的纵向联系：交叉滞后中介分析
Shuojia Wang,Zikuan Yang,Yilin Chen et al.
Shuojia Wang et al.
Background: Previous studies have reported an association between multimorbidity and cognitive function, however, the specific direction and underlying mechanism remain unclear. The study aimed to explore the direction of...
Associations of periodontitis with biological aging among US adults: An exploratory mediation analysis via lactate [0.03%]
牙周病与美国成年人生物衰老的关联性：通过乳酸进行的探索性中介分析
Huan Zhou,Yong Li,Di Miao et al.
Huan Zhou et al.
Background: To investigate the potential role of lactate in the relationship between periodontitis and biological aging. Methods: Cross...