Impact of Dementia, Depression, and Other Mental Disorders on Reoperation and Mortality among Hip Fracture Patients: A Nationwide Danish Cohort Study [0.03%]
痴呆、抑郁和其他精神疾病对骨折患者的影响：一项丹麦全国队列研究
Simon Storgaard Jensen,Per Hviid Gundtoft,Jan-Erik Gjertsen et al.
Simon Storgaard Jensen et al.
Background: Despite the rising global burden of mental disorders, their impact on complication risk following hip fracture surgery remains unclear. We examined reoperation and mortality risks after hip fracture surgery, i...
Brain resting-state functional connectivity mediates the age-associated decline in physical activity engagement [0.03%]
大脑静息态功能连接在年龄与身体活动减少之间的中介作用
Meishan Ai,Emma M Tinney,Goretti España-Irla et al.
Meishan Ai et al.
Background: Physical activity (PA) engagement declines with age in late adulthood. Therefore, understanding factors underlying PA engagement is needed for PA promotion in older adults. Executive function is a potential ke...
Strategies to minimize fall-related injuries in older adults at risk of falls: the Falling Safely Training (FAST) study [0.03%]
针对跌倒高风险老年人减少跌倒相关损伤的策略研究：安全跌倒训练（FAST）项目
Tobia Zanotto,Lingjun Chen,James R Fang et al.
Tobia Zanotto et al.
Background: Falls are the leading cause of accidental injury among older adults. Current fall prevention programs are useful but do not target the key variable for injury (i.e., impact force). An approach, which has shown...
The effect of vitamin D3 supplementation on the incidence of diagnosed dementia among healthy older adults - the Finnish Vitamin D Trial [0.03%]
维生素D3补充对健康老年人认知障碍发生率的影响——芬兰维生素D试验结果
Eija Lönnroos,Maija Ylilauri,Christel Lamberg-Allardt et al.
Eija Lönnroos et al.
Background: Some short-term vitamin D supplementation trials suggest benefits on cognitive performance, but apart from observational studies, there is little evidence whether long-term vitamin D supplementation can preven...
Submaximal eccentric training during immobilization does not prevent serial sarcomere loss or impairments in mechanical function in old or young rats [0.03%]
在固定期间进行次最大离心训练不能预防老年或年轻大鼠的串联肌小节丢失或机械功能障碍
Avery Hinks,Ethan Vlemmix,Geoffrey A Power
Avery Hinks
The age-related loss of muscle mass is partly driven by a reduction in serial sarcomere number (SSN), and further SSN loss occurs during immobilization. SSN is associated with optimal force and power production and muscle passive tension, t...
Cardiovascular-derived Circulating Cell-Free DNA Fragments are Associated with Frailty and Increased Cardiovascular Events in Older Adults [0.03%]
心血管来源的循环细胞游离DNA片段与老年人的衰弱和增加的心血管事件有关
Lolita S Nidadavolu,David W Sosnowski,Nikita Sivakumar et al.
Lolita S Nidadavolu et al.
Increased cellular damage in aging tissues releases circulating cell-free genomic DNA (ccf-gDNA) into the bloodstream, and these fragments are associated with a higher risk of frailty and dementia. We hypothesized that identifying the tissu...
Preoperative Plasma p-tau231，p-tau181 and p-tau217 are associated with Postoperative Delirium: a prospective study [0.03%]
术前血浆中p-tau231、p-tau181和p-tau217与术后谵妄的相关性：一项前瞻性研究
Li Xue Wu,Jia Bao Su,Guang Ling Li et al.
Li Xue Wu et al.
Background: The pathophysiology of delirium remains incompletely understood. The relationship between preoperative plasma concentrations of p-tau181, p-tau231, p-tau217, and T-tau proteins and postoperative delirium needs...
Motoric cognitive risk syndrome and risk of cardiovascular disease: a population-based study [0.03%]
运动性认知障碍风险综合征与心血管疾病发病风险：一项基于人群的研究
Charlotte Menart,Amber Yaqub,Lisanne Dommershuijsen et al.
Charlotte Menart et al.
Background: To investigate whether differences between motoric cognitive risk syndrome (MCRS) and mild cognitive impairment (MCI) are of vascular origin, we compared the risk of incident cardiovascular disease in both gro...
Validation of the Candrive Older Driver Risk Stratification Tool for Assessing Medical Fitness-to-Drive in Older Australian Drivers [0.03%]
评估Candrive工具在评定澳大利亚老年驾驶员驾驶能力方面的有效性
Judith L Charlton,Sjaan Koppel,Amanda Stephens et al.
Judith L Charlton et al.
Background: Assessing older drivers' fitness-to-drive (FTD) is challenging, with decisions impacting mobility and health. This study aimed to validate the Candrive older driver risk stratification tool (RST) for screening...
Mortality Trends in Pre-COVID-19 and COVID-19 Eras Among Oldest Veterans [0.03%]
新冠疫情前后最年长退伍军人的死亡率趋势
Jessica Palmer,Maithri Kondapaka,Brock A Beamer et al.
Jessica Palmer et al.
Background: The COVID-19 pandemic has had a profound impact on older adults, particularly those with existing comorbidities. To inform targeted healthcare strategies for this heterogeneous group, this study seeks to analy...