Xin Wen Ong,David G Le Couteur,Louise M Waite et al.
Xin Wen Ong et al.
Background: As the aging population grows, the care provided to patients with dementia at the end of life represents a critical area of geriatric and palliative care. This study aimed to describe the care provided to hosp...
Impact of Socioeconomic Conditions Across the Life Course on Epigenetic Age Acceleration: Evidence from a Longitudinal Cohort [0.03%]
生命周期社会经济状况对表观遗传学年龄加速的影响——来自纵向队列的证据
Leah Moubadder,Junyu Chen,Elizabeth S Clausing et al.
Leah Moubadder et al.
Background: We investigated whether adulthood socioeconomic status (SES) mediates the association between childhood SES and biological aging in a longitudinal cohort (N = 359). ...
Jacinta Correia,Promit Sinha Roy,Kaitlyn G Holden et al.
Jacinta Correia et al.
Emerging evidence highlights the critical role of cellular metabolism in immune cell activation, development, and function. Peroxisomes, key metabolic organelles, maintain metabolic homeostasis, yet their role in immune cells remains undere...
Therapeutic Approaches to Delay Lung Aging: Understanding Cellular and Immune System Changes in the Older Adults [0.03%]
延缓肺部衰老的治疗途径：了解老年人细胞和免疫系统的变化
Yumeng Lin,Mengjun Yan,Lili Shen et al.
Yumeng Lin et al.
As human lifespan extends, the impact of aging on health has become a significant research area, with increasing focus on pulmonary health. The lung, as a complex organ, undergoes various microenvironmental changes during aging, which are c...
Michael Joseph S Dino,Kenneth W Dion,Peter M Abadir et al.
Michael Joseph S Dino et al.
Background: The Fourth and Fifth Industrial Revolutions have introduced new and innovative technologies, such as artificial intelligence and virtual humanoids (VH), that offer promising solutions to health challenges amon...
Identifying Motor Resilience Proteins Associated with Motor Decline in Older Adults [0.03%]
与老年人运动功能下降相关的运动耐受性蛋白质的鉴定
Aron S Buchman,Tianhao Wang,Katia de Paiva Lopes et al.
Aron S Buchman et al.
Background: This study will identify cortical proteins that may provide motor resilience, the capacity to maintain motor function despite underlying ADRD pathologies. ...
Systematic identification of exercise-induced anti-aging processes involving intron retention [0.03%]
系统识别锻炼引起的与内含子保留相关的抗衰老过程
Hayata Kodama,Hirotaka Ijima,Yusuke Matsui
Hayata Kodama
Exercise is one of the most promising anti-aging interventions for maintaining skeletal muscle health in older adults. Nine "Aging Hallmarks", proposed by López-Otín, offer insights into the aging process; however, the link between these ...
Cumulative loneliness and memory function among US older adults: the role of depressive symptoms [0.03%]
累积性孤独对美国老年人认知功能的影响：抑郁症状的中介作用
Xuexin Yu,Adina Zeki Al Hazzouri,Tsai-Chin Cho et al.
Xuexin Yu et al.
Background: This study aimed to investigate whether depressive symptoms mediate the association between cumulative loneliness and memory function during aging. ...
Does Lower Oxidative Capacity Influence the Relative Contributions of ATP-Producing Pathways During Muscular Work in Aging? [0.03%]
氧化能力下降对衰老期间肌肉活动中各种产ATP途径的相对贡献有影响吗？
Zoe H Smith,Liam F Fitzgerald,Rajakumar Nagarajan et al.
Zoe H Smith et al.
Although the capacity of skeletal muscle to produce ATP via oxidative phosphorylation may decrease in some muscles in older age, the influence of a lower capacity on relative use of oxidative and non-oxidative ATP production pathways in viv...
Increased levels of Aβ40 in plasma is associated with severity of exposure to airborne pollutants at the World Trade Center: A cross-sectional study of neurological biomarkers [0.03%]
血浆Aβ40水平与世界贸易中心空气污染暴露的神经生物学标志物横断面研究
Alissa Barber,Ryan Chacon,Frank D Mann et al.
Alissa Barber et al.
World Trade Center (WTC) responders who were more severely exposed to the airborne pollution while working in rescue and recovery work would have heightened circulating levels of β-Amyloid (Aβ) levels in plasma. Plasma for 905 World Trade...