Oropharyngeal Microbiome Alterations in Sarcopenia: A Nested Case-Control Study in Older Adults [0.03%]
老年人肌少症患者的口腔微生物组变化：一项病例对照研究
Runjie Li,Wenhua Jiang,Huiyu Tang et al.
Runjie Li et al.
Background: Sarcopenia, associated with systemic inflammation, respiratory diseases, and known gut dysbiosis, poses a significant health burden. However, the role of the nasopharyngeal and oropharyngeal (NP/OP) microbiome...
Infusion of peripheral blood mononuclear cell alleviates amyloid accumulation and cognitive deficits in Alzheimer's disease [0.03%]
外周血单个核细胞的输入可改善阿尔茨海默病患者的淀粉样蛋白累积和认知缺陷
Lu-Lu Xue,Ya-Qi Yang,Ruo-Lan Du et al.
Lu-Lu Xue et al.
Recently, the role of peripheral blood mononuclear cells (PBMCs) in neurodegenerative activities has garnered significant attention, yet the role in Alzheimer's disease (AD) remains unclear. Based on our previous single-cell RNA sequencing ...
Effect of Aspirin on Grip Strength and Gait Speed in Community-Dwelling Older Adults in the ASPirin in Reducing Events in the Elderly (ASPREE) Study [0.03%]
阿司匹林对社区老年人握力和步速影响的横断面分析：ASPREE研究
Aung Zaw Zaw Phyo,Sara E Espinoza,Suzanne G Orchard et al.
Aung Zaw Zaw Phyo et al.
Background: Grip strength and gait speed are key markers of physical functional capacity and general health in older people. This study aimed to examine the effect of low-dose aspirin on hand-grip strength and habitual ga...
Poor Olfaction and Risk of Heart Failure in the Atherosclerosis Risk in Communities Study [0.03%]
社区动脉粥样硬化风险研究中嗅觉缺失与心力衰竭发病的关系
Keran W Chamberlin,Chenxi Li,Anna Kucharska-Newton et al.
Keran W Chamberlin et al.
Background: Poor olfaction may be associated with incident heart failure (HF) in older adults, but empirical evidence is scant. Methods: ...
Beyond Nephrology: FGF-23 as a Predictive Biomarker for Frailty and Adverse Outcomes in Older Adults [0.03%]
超越肾病范围：FGF-23作为老年脆弱和不良结局的预测生物标志物
Concepción-Zavaleta Marcio José,Cabellos Acuña Eduardo,Fuentes-Mendoza Jenyfer et al.
Concepción-Zavaleta Marcio José et al.
Racial/ethnic differences in the association of lifestyle factors with biological aging in NHANES, 1999-2018 [0.03%]
基于NHANES(1999-2018)的生活方式因素与生物学衰老之间关联的种族和民族差异分析
Talha Arif,Aline Thomas,Daniel W Belsky et al.
Talha Arif et al.
Racial and ethnic disparities in healthy aging represent an emerging public health crisis that will only grow worse as our population grows older. Healthy lifestyle behaviors are proposed as a key strategy to promote healthy aging. However,...
A novel information theoretic approach reveals loss of effective biomolecular communication in aging muscle cells [0.03%]
一种新颖的信息理论方法揭示了老化肌肉细胞中有效生物分子通讯的丧失
Sruthi Sivakumar,Ryan William LeFebre,Giulia Menichetti et al.
Sruthi Sivakumar et al.
Maintenance of organismal function requires tightly regulated biomolecular communication. However, with aging, communication deteriorates, thereby disrupting effective information flow. Using information theory applied to skeletal muscle si...
Rethinking the relationship between ambulatory activity and falls in long-term care: Risk versus reward [0.03%]
反思长期护理中门诊活动与跌倒之间的关系：风险与收益的再思考
Ríona Mc Ardle,Lynne Taylor,Silvia Del Din et al.
Ríona Mc Ardle et al.
Background: Ambulatory older residents in long-term care(LTC) have the highest risk of falling. However, the relationship between ambulatory activity (steps per day) and fall risk in LTC is unclear. This study examined wh...
Living in Historically Redlined Neighborhoods and Biological Aging among Older Adults [0.03%]
居住在历史上的红色标记社区与老年人的生物学老化的关系
Calley E Fisk,Katrina M Walsemann,Chelsey Jones et al.
Calley E Fisk et al.
Living in historically redlined neighborhoods has deleterious effects on aging-related health outcomes, yet little is known about how historical redlining affects the physiological aging process and the role of current neighborhood socioeco...
The interplay between perceived fatigability, intrinsic capacity and physical activity: network analysis in a British birth cohort study [0.03%]
基于英国出生队列研究的感知疲劳与内在能力及身体活动之间的相互作用：网络分析
Kaisa Koivunen,Lotta Palmberg,Gabriela Lunansky et al.
Kaisa Koivunen et al.
Background: Fatigability-an individual's susceptibility to fatigue when performing standardized activities-may arise from diminished functional reserves and contribute to reduced physical activity levels, potentially rein...