Leisure activity engagement and depressive symptoms: Meta-analysis of 11 studies of middle-aged and older twins aged 32-99 [0.03%]
休闲活动参与和抑郁症状的关系：中老年人双胞胎研究的 meta 分析（共纳入 11 篇文献，涉及年龄为 32 岁至 99 岁）
Marianne Nygaard,Miriam A Mosing,Deborah G Finkel et al.
Marianne Nygaard et al.
Background: Leisure activity is associated with a wide range of physical and mental health outcomes. Nonetheless, the causal basis for these associations is uncertain and we do not fully understand why some individuals ar...
Accelerated Biological Aging and Midlife Frailty among U.S. Military Veterans [0.03%]
美国退伍军人的加速生物衰老与中年脆弱性
Kyle J Bourassa,Kirsten H Dillon,Rachel L Rodriguez et al.
Kyle J Bourassa et al.
Injuries characterizing recent military service, such as traumatic brain injury and posttraumatic stress disorder, are linked to accelerated biological aging. If recent veterans have accelerated aging, they might also show early onset of ag...
Association between a dietary-based micronutrient adequacy index and hearing loss in community-dwelling older adults [0.03%]
基于饮食的微量营养素充足指数与社区居住老年人听力损失之间的关系
Humberto Yévenes-Briones,Erika Tapia-Portilla,Veronica Vega-Cabello et al.
Humberto Yévenes-Briones et al.
Background: The effect of dietary micronutrient adequacy on hearing loss is unknown. The aim of this study was to examine the cross-sectional association between dietary micronutrient adequacy and hearing loss among commu...
Nahed El Kassar,Amy E DeZern,Janis Abkowitz et al.
Nahed El Kassar et al.
Approximately 17% of people aged 65 years and older are anemic, and 10% of death certificates report anemia as a secondary cause of death in the US. Nonetheless, anemia remains unexplained in 30-50% of older adults. This unexplained anemia ...
Reproductive Factors and Risk of Mortality in Older Women: A 16-year Follow-up of Guangzhou Biobank Cohort Study [0.03%]
生殖因素与老年女性死亡风险的关系——广州生物库队列研究16年随访结果
Jia Liu,Wei Xiang Gao,Wei Sen Zhang et al.
Jia Liu et al.
Background: China's dramatic decline in fertility rates due to family planning policies and socioeconomic changes have significant impacts on women's long-term health. We examined the associations of individual reproducti...
The Association Between Hearing Impairment and Incident Depression in Older Adults: A Longitudinal Analysis [0.03%]
老年听力损伤和抑郁症的纵向分析研究
Malcolm P Forbes,Mark W Cox,Katharine Brewster et al.
Malcolm P Forbes et al.
Background: Hearing loss (HL) is common in older adults and is associated with several adverse health outcomes. Although previous research has demonstrated a link between hearing impairment and depression, most studies ha...
Picolinic acid, a tryptophan metabolite, exhibits anabolic effects in muscle cells and improves lifespan and movement in C. elegans [0.03%]
色氨酸代谢产物吡哆酸通过作用于肌肉细胞发挥促合成代谢效应并改善秀丽隐杆线虫的寿命和运动能力
Daniel Rivas,Ivan Baltasar-Fernandez,Abdelrahman AlOkda et al.
Daniel Rivas et al.
Compounds promoting anabolic effects on muscle and bone may offer an ideal treatment for osteosarcopenia while potentially impacting healthspan and lifespan. We previously demonstrated the anabolic effects of picolinic acid (PIC), a tryptop...
Pain as a Precursor: Elevated Risk of Chronic Disease Development in Older Adults - Findings from Dual Aging Prospective Cohort Studies and Mendelian Randomization Analysis [0.03%]
疼痛作为前兆：老年慢性病高风险性的前瞻性队列研究及孟德尔随机化分析结果
Lulin Ma,Jing Shen,Fang Cheng et al.
Lulin Ma et al.
Background: The relationship between pain characteristics and chronic disease development in aging populations remains poorly understood. This study explored associations between early pain exposure and incident chronic d...
Late-life Disability following the Action for Health in Diabetes (Look AHEAD) Trial [0.03%]
行动糖尿病（看Ahead）试验后晚期生活残疾事件
Charles T Semelka,Rebecca H Neiberg,HarLeigh D Haynie et al.
Charles T Semelka et al.
Background: Obesity increases risks for mobility limitations and disability in older adults. We examined the long-term effects of an intensive lifestyle intervention (ILI) versus diabetes support and education (DSE) and b...
Malnutrition and Age-Related Macular Degeneration: Mechanistic Insights from UK Biobank Metabolomic and Imaging Data [0.03%]
英国生物银行代谢组学和影像数据揭示的营养不良与年龄相关性黄斑变生之间的关系：机制启示
Jingxin Zhou,Yingcheng He,Jiawei Wang et al.
Jingxin Zhou et al.
Background: Malnutrition, characterized by degeneration of body composition due to reduced intake or inflammation, shares some common mechanisms with age-related macular degeneration (AMD), while their associations remain...