Benzodiazepine Exposure and 6-Month Mortality in Older Adults Post-Hospitalization: Time to Consider Deprescribing? [0.03%]
老年人出院后的苯二氮平暴露与半年死亡率：是时候考虑减少用药了吗？
Federico Bellelli,Maria Cristina Ferrara,Alice Margherita Ornago et al.
Federico Bellelli et al.
Background: Benzodiazepines (BZDs) are commonly used in older populations despite their association with multiple adverse outcomes. However, the impact of continuing versus deprescribing BZDs during hospitalization on sho...
Sleep Quality as a Modifier of Plasma pTau217 and GFAP Associations with Cognitive Function [0.03%]
睡眠质量作为血浆pTau217和GFAP与认知功能关联的修饰因素
Ramkrishna K Singh,Semere Bekena,Yiqi Zhu et al.
Ramkrishna K Singh et al.
Background: Plasma biomarkers, such as neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), phosphorylated tau (pTau217), and total tau (tTau), are associated with cognitive decline. However, the role ...
Bidirectional Relationships between Pain and Alcohol Use among Older Adults: A Scoping Review [0.03%]
老年人疼痛与饮酒的双向关系：综述研究
Lisa R Larowe,Heily Chavez Granados,Lisa L Philpotts et al.
Lisa R Larowe et al.
Background: Pain and alcohol use are highly prevalent and frequently co-occur among older adults. An established reciprocal model suggests that pain and alcohol use interact in the manner of a positive feedback loop. Howe...
Preclinical Mobility Limitations Amongst Community Dwelling Older Adults Using the National Health and Aging Trends Study [0.03%]
基于全国健康和老龄化趋势研究的社区老年人前期行动能力限制状况
Pallavi Tyagi,Luisa Franzini,Jie Chen
Pallavi Tyagi
Background: Preclinical Mobility Limitations (PCML) represent an early transitional stage in which individuals compensate for functional decline, yet do not exhibit overt disability. Recognition of PCML may identify indiv...
Impact of Traumatic Brain Injury on Recovery over the Year Following Hip Fracture among Older Medicare Beneficiaries [0.03%]
老年医疗保险受益人在髋部骨折后一年内创伤性脑损伤对其恢复的影响
Jennifer S Albrecht,Jay S Magaziner,Jason R Falvey
Jennifer S Albrecht
Background: Traumatic brain injury (TBI) is a serious full-related injury that could occur simultaneously during the fall that resulted in hip fracture. The objective of the current study was to estimate the impact of TBI...
Single-cell RNA sequencing analysis combined with bulk RNA sequencing revealed changes in the micro-environment of bone marrow aging [0.03%]
结合单细胞和bulk测序分析揭示骨髓微环境的衰老变化规律
Qifan Li,Zhiqiang Shao,Cheng Chen et al.
Qifan Li et al.
Aging cells in the bone marrow contribute to bone aging and related diseases. By combining single-cell and bulk RNA analysis, we aim to better understand the changes in the bone marrow micro-environment caused by aging. We established singl...
The final year for community-dwelling older adults with dementia in an Asian setting: admissions, interventions, and caregiver burden [0.03%]
亚洲社区居住痴呆老人生命最后一年的住院、干预和照料者负担
Ellie B Andres,Chetna Malhotra;PISCES Study Group
Ellie B Andres
Background: Current understanding of the last year of life with dementia is disproportionately informed by studies conducted in western contexts, primarily within long-term care settings. This study examines the last year...
Short-Term PM2.5 Exposure and Mortality in Older Adults with Asthma in South Korea [0.03%]
短期暴露于细颗粒物与韩国老年哮喘患者死亡率的关系
Sun Jae Park,Hyeokjong Lee,Min Chae Kim et al.
Sun Jae Park et al.
Background: Despite growing concerns over the adverse health effects of air pollution, research on the mortality risk associated with exposure to fine particulate matter (PM) in older adults with asthma remains limited. T...