Near-infrared light and magnetic field dual-responsive 3D printed scaffolds for sequential treatment of infected bone defects [0.03%]
近红外光和磁场双响应的3D打印支架用于感染性骨缺损的序贯治疗
Dapeng Zeng,Hao Wang,Zehao Yu et al.
Dapeng Zeng et al.
The treatment of infected bone defects remains a challenge due to the complex biological processes involved, including antibacterial, anti-inflammatory, angiogenesis and bone regeneration. Polyetherimide (PEI) has promising applications in ...
Biohybrid microstructured hydrogels obtained via in situ extracellular matrix deposition and decellularization using supercritical CO2 [0.03%]
基于超临界二氧化碳脱细胞的原位沉积微结构化生物杂化水凝胶
Vanessa Morais Lima,Albane Carré,Emmanuelle Poque et al.
Vanessa Morais Lima et al.
In recent decades, our understanding of biomaterials has shifted from seeing them simply as physical supports for cells or drug delivery platforms to recognizing their active and dynamic role in tissue repair, guided by their physicochemica...
Core-shell microbead-based 3D vascularized glioma tumor model for effective drug testing [0.03%]
基于核心-壳微球的三维血管化胶质瘤肿瘤模型用于有效的药物测试
Xiuxiu Zhang,Zixian Wang,Zeyang Liu et al.
Xiuxiu Zhang et al.
The 3D hydrogel-based tumor model shows promise in recapitulating the physiology of in vivo tumor environments for mechanistic studies and drug testing. However, the challenge remains in effectively mimicking a vascularized microtumor with ...
3D printed osteochondral lineage-specific biphasic scaffolds for functional repair of full-thickness articular cartilage defects in weight-bearing area [0.03%]
用于负重区全层关节软骨缺损功能性修复的具有成骨/成软骨谱系特异性的3D打印双相支架
Shengnan Qin,Wen Wang,Liang Chen et al.
Shengnan Qin et al.
Functional repair of full-thickness defects in the weight-bearing articular cartilage has been one of the major challenges in orthopeadics. Whereas the advanced 3D printing technique allows the construction of bionic bioscaffolds that suppo...
F Bracco,G Zanderigo,K Paynabar et al.
F Bracco et al.
Bioprinting is a promising family of processes combining 3D printing with life sciences, offering the potential to significantly advance various applications. Despite numerous research efforts aimed at enhancing process modeling, optimizing...
Advances in cell spheroid technology towards complex tissue formation guided by microfabrication and biomaterial innovations [0.03%]
基于微加工和生物材料创新的类器官技术在复杂组织构建中的应用及进展
Rabi Ibrahim Saleh,Chaenyung Cha
Rabi Ibrahim Saleh
Spheroids have become a de facto model three-dimensional (3D) tissue for studying various biological phenomena. While the technology to produce spheroids has become highly accessible and is routinely used by researchers, it has quite a long...
A photosynthetic egg based oxygen-releasing platform to promote angiogenesis and tissue regeneration in diabetic wounds [0.03%]
一种光合作用卵形氧释放平台促进糖尿病伤口血管生成和组织再生
Yu He,Ying Zhao,Xingtang Niu et al.
Yu He et al.
Diabetic wounds represent a longstanding global health challenge attributable to tissue hypoxia resulting from impaired microcirculation, which impedes crucial physiological processes essential for wound healing, such as cell proliferation ...
3D bioprinted GelMA/collagen hydrogel for corneal stroma regeneration [0.03%]
用于角膜基质再生的3D生物打印GelMA/胶原蛋白水凝胶
Yingni Xu,Wenfang Liu,Qi Zhao et al.
Yingni Xu et al.
Blindness caused by corneal stroma disease affects millions worldwide, the regeneration of corneal stroma has always been a challenge due to its sophisticated curvature structure and keratocyte-fibroblast transformation. In this study, we d...
Osteochondral organoid biofabrication: construction strategies, applications and perspectives [0.03%]
软骨组织工程构造体的生物制造：构建策略、应用及展望
Liwei Fu,Jiang Wu,Zhichao Zhang et al.
Liwei Fu et al.
Osteochondral tissue is a functional complex with crosstalk shown to occur between cartilage and subchondral bone, playing a pivotal role in joint function and mobility. Osteochondral tissue repair has long been an enormous challenge in reg...
Intervertebral disc spheroids as an in vitro multicellular platform for recapitulating the microenvironment of intervertebral disc degeneration [0.03%]
用于再现椎间盘退变微环境的椎间盘球体的多细胞平台
Tae-Won Kim,An-Gi Kim,Min-Ho Hwang et al.
Tae-Won Kim et al.
Intervertebral disc (IVD) degeneration (IVDD) is a major contributor to chronic low back pain (LBP), representing a substantial burden on the spinal healthcare system and serving as a leading cause of long-term disability worldwide. Biomime...