Dishary Banerjee,Margarita M Ivanova,Nazmiye Celik et al.
Dishary Banerjee et al.
Gaucher disease (GD), the most prevalent lysosomal disorder, is caused byGBA1gene mutations, leading to deficiency of glucocerebrosidase, and accumulation of glycosphingolipids in cells of the mononuclear phagocyte system. While skeletal di...
Gastrointestinal organs and organoids-on-a-chip: advances and translation into the clinics [0.03%]
芯片上的胃肠器官和类器官：进展与临床转化
Mariana R Carvalho,Le-Ping Yan,Bo Li et al.
Mariana R Carvalho et al.
Microfluidic organs and organoids-on-a-chip models of human gastrointestinal systems have been established to recreate adequate microenvironments to study physiology and pathophysiology. In the effort to find more emulating systems and less...
Is it possible to 3D bioprint load-bearing bone implants? A critical review [0.03%]
关于负重骨植入物的3D生物打印:批判性综述
Tanmay Gupta,Subrata Bandhu Ghosh,Sanchita Bandyopadhyay-Ghosh et al.
Tanmay Gupta et al.
Rehabilitative capabilities of any tissue engineered scaffold rely primarily on the triad of (i) biomechanical properties such as mechanical properties and architecture, (ii) chemical behavior such as regulation of cytokine expression, and ...
Double-layered blood vessels over 3 mm in diameter extruded by the inverse-gravity technique [0.03%]
一种反重力技术打印的直径超过3毫米的双层血管模型
Van Thuy Duong,Chanh Trung Nguyen,Huu Lam Phan et al.
Van Thuy Duong et al.
One of the most promising techniques for treating severe peripheral artery disease is the use of cellular tissue-engineered vascular grafts (TEVGs). This study proposes an inverse-gravity (IG) extrusion technique for creating long double-la...
A scalable human iPSC-based neuromuscular disease model on suspended biobased elastomer nanofiber scaffolds [0.03%]
一种可扩展的人类 iPSC 基因型和表型神经肌肉疾病模型的悬滴生物基弹性体纳米纤维支架
Aimee Cheesbrough,Peter Harley,Federica Riccio et al.
Aimee Cheesbrough et al.
Many devastating neuromuscular diseases currently lack effective treatments. This is in part due to a lack of drug discovery platforms capable of assessing complex human neuromuscular disease phenotypes in a scalable manner. A major obstacl...
Physically-based simulation of elastic-plastic fusion of 3D bioprinted spheroids [0.03%]
基于物理的三维生物打印类球体弹性塑性融合仿真模型
Hassan Bahrami,Federico Sichetti,Enrico Puppo et al.
Hassan Bahrami et al.
Spheroids are microtissues containing cells organized in a spherical shape whose diameter is usually less than a millimetre. Depending on the properties of the environment they are placed in, some nearby spheroids spontaneously fuse and gen...
Development and characterization of biological sutures made of cell-assembled extracellular matrix [0.03%]
基于细胞组装的生物蛋白 glue 制备及其性能研究
Paul Borchiellini,Adeline Rames,François Roubertie et al.
Paul Borchiellini et al.
Most vascular surgical repair procedures, such as vessel anastomoses, requires using suture materials that are mechanically efficient and accepted by the patient's body. These materials are essentially composed of synthetic polymers, such a...
Jinyoung Kim,Junghoon Kim,Yoonhee Jin et al.
Jinyoung Kim et al.
Thein vitrosimulation of organs resolves the accuracy, ethical, and cost challenges accompanyingin vivoexperiments. Organoids and organs-on-chips have been developed to model thein vitro, real-time biological and physiological features of o...
Sequentially suspended 3D bioprinting of multiple-layered vascular models with tunable geometries for in vitro modeling of arterial disorders initiation [0.03%]
用于体外模拟动脉疾病发生的可调几何形状的多层血管模型的连续悬浮式三维生物打印技术
Chen Pan,Jingwen Xu,Qiqi Gao et al.
Chen Pan et al.
As the main precursor of arterial disorders, endothelial dysfunction preferentially occurs in regions of arteries prone to generating turbulent flow, particularly in branched regions of vasculatures. Although various diseased models have be...
Sacrificial scaffold-assisted direct ink writing of engineered aortic valve prostheses [0.03%]
用于工程化主动脉瓣假体的 sacrificial 印迹辅助直接墨水书写技术
Cheng Zhang,Jiangtao Hao,Weiliang Shi et al.
Cheng Zhang et al.
Heart valve disease has become a serious global health problem, which calls for numerous implantable prosthetic valves to fulfill the broader needs of patients. Although current three-dimensional (3D) bioprinting approaches can be used to m...