Human vascularized bile duct-on-a chip: a multi-cellular micro-physiological system for studying cholestatic liver disease [0.03%]
血管化的人胆管芯片:一种用于研究肝胆汁淤积的多细胞微生理系统
Yu Du,Iris E M de Jong,Kapish Gupta et al.
Yu Du et al.
Exploring the pathogenesis of and developing therapies for cholestatic liver diseases such as primary sclerosing cholangitis (PSC) remains challenging, partly due to a paucity ofin vitromodels that capture the complex environments contribut...
A 3D-printed blood-brain barrier model with tunable topology and cell-matrix interactions [0.03%]
一种拓扑和细胞基质相互作用可调的3D打印脑血管模型
Louis S Paone,Mohammed Mehdi Benmassaoud,Aidan Curran et al.
Louis S Paone et al.
Recent developments in digital light processing (DLP) can advance the structural and biochemical complexity of perfusablein vitromodels of the blood-brain barrier. Here, we describe a strategy to functionalize complex, DLP-printed vascular ...
3D-printed biomimetic scaffolds with precisely controlled and tunable structures guide cell migration and promote regeneration of osteochondral defect [0.03%]
具有精确可控和可调结构的3D打印仿生支架引导细胞迁移并促进软骨骨缺损再生
Yuqing Gu,Yiwei Zou,Yuxuan Huang et al.
Yuqing Gu et al.
Untreated osteochondral defects will develop into osteoarthritis, affecting patients' quality of life. Since articular cartilage and subchondral bone exhibit distinct biological characteristics, repairing osteochondral defects remains a maj...
On the reproducibility of extrusion-based bioprinting: round robin study on standardization in the field [0.03%]
基于挤出的生物打印的可重复性:标准化领域的圆桌研究
David Grijalva Garces,Svenja Strauß,Sarah Gretzinger et al.
David Grijalva Garces et al.
The outcome of three-dimensional (3D) bioprinting heavily depends, amongst others, on the interaction between the developed bioink, the printing process, and the printing equipment. However, if this interplay is ensured, bioprinting promise...
Translational biomaterials of four-dimensional bioprinting for tissue regeneration [0.03%]
四维生物打印组织再生转化生物材料的研究进展
Leah Faber,Anne Yau,Yupeng Chen
Leah Faber
Bioprinting is an additive manufacturing technique that combines living cells, biomaterials, and biological molecules to develop biologically functional constructs. Three-dimensional (3D) bioprinting is commonly used as anin vitromodeling s...
Bioinspired 3D-printed scaffold embedding DDAB-nano ZnO/nanofibrous microspheres for regenerative diabetic wound healing [0.03%]
一种用于再生糖尿病伤口愈合的仿生3D打印支架(embedding DDAB-纳米ZnO/纳纤素微球)
Walaa M Metwally,Salma E El-Habashy,Lobna S El-Hosseiny et al.
Walaa M Metwally et al.
There is a constant demand for novel materials/biomedical devices to accelerate the healing of hard-to-heal wounds. Herein, an innovative 3D-printed bioinspired construct was developed as an antibacterial/regenerative scaffold for diabetic ...
Maxwell B Nagarajan,Alexander J Ainscough,Daniel S Reynolds et al.
Maxwell B Nagarajan et al.
Rete ridges consist of undulations between the epidermis and dermis that enhance the mechanical properties and biological function of human skin. However, most human skin models are fabricated with a flat interface between the epidermal and...
Mimicking sarcolemmal damage in vitro: a contractile 3D model of skeletal muscle for drug testing in Duchenne muscular dystrophy [0.03%]
一种收缩的三维骨骼肌模型:用于药物筛选的体外肌肉损伤模型
Ainoa Tejedera-Villafranca,Marisol Montolio,Javier Ramón-Azcón et al.
Ainoa Tejedera-Villafranca et al.
Duchenne muscular dystrophy (DMD) is the most prevalent neuromuscular disease diagnosed in childhood. It is a progressive and wasting disease, characterized by a degeneration of skeletal and cardiac muscles caused by the lack of dystrophin ...
3D bioprinted endothelial cell-microglia coculture for diabetic retinopathy modeling [0.03%]
用于糖尿病视网膜病变建模的3D生物打印的内皮细胞-小胶质细胞共培养系统
Haixiang Wu,Fangcheng Xu,Yunfang Luo et al.
Haixiang Wu et al.
Diabetic retinopathy (DR) is a common diabetes complication leading to vision impairment or blindness due to retinal vasculature alterations. Hyperglycemia induces structural alterations, inflammation, and angiogenic factor upregulation. Cu...
3D-bioprintable endothelial cell-laden sacrificial ink for fabrication of microvessel networks [0.03%]
用于微血管网络构建的可生物打印的内皮细胞 Sacrificial 墨水
Kun-Chih Cheng,Patrick Theato,Shan-Hui Hsu
Kun-Chih Cheng
Although various research efforts have been made to produce a vascular-like network structure as scaffolds for tissue engineering, there are still several limitations. Meanwhile, no articles have been published on the direct embedding of ce...