A vascularized 3D model of the human pancreatic islet for ex vivo study of immune cell-islet interaction [0.03%]
可用于研究胰岛与免疫细胞之间相互作用的三维人胰岛血管模型
R Hugh F Bender,Benjamen T O&#x;Donnell,Bhupinder Shergill et al.
R Hugh F Bender et al.
Insulin is an essential regulator of blood glucose homeostasis that is produced exclusively byβcells within the pancreatic islets of healthy individuals. In those affected by diabetes, immune inflammation, damage, and destruction of islet...
Fatemeh Rasti Boroojeni,Sajjad Naeimipour,Philip Lifwergren et al.
Fatemeh Rasti Boroojeni et al.
In native tissue, remodeling of the pericellular space is essential for cellular activities and is mediated by tightly regulated proteases. Protease activity is dysregulated in many diseases, including many forms of cancer. Increased proteo...
Cell viability prediction and optimization in extrusion-based bioprinting via neural network-based Bayesian optimization models [0.03%]
基于神经网络贝叶斯优化模型的挤出式生物打印中的细胞活力预测与优化
Dorsa Mohammadrezaei,Lena Podina,Johanna De Silva et al.
Dorsa Mohammadrezaei et al.
The fields of regenerative medicine and cancer modeling have witnessed tremendous growth in the application of 3D bioprinting. Maintaining high cell viability throughout the bioprinting process is crucial for the success of this technology,...
Micro-nano hierarchical scaffold providing temporal-matched biological constraints for tendon reconstruction [0.03%]
用于韧带重建的时空匹配生物约束的微纳米分级支架
Xiaojing Xie,Junjie Xu,Jing Lin et al.
Xiaojing Xie et al.
Due to the limitations of tendon biology, high-quality tendon repair remains a clinical and scientific challenge. Here, a micro-nano hierarchical scaffold is developed to promote orderly tendon regeneration by providing temporal-matched bio...
Lvyang Zhu,Qu Tang,Zhenzhen Mao et al.
Lvyang Zhu et al.
Intercellular communication is critical to the understanding of human health and disease progression. However, compared to traditional methods with inefficient analysis, microfluidic co-culture technologies developed for cell-cell communica...
Highly compliant biomimetic scaffolds for small diameter tissue-engineered vascular grafts (TEVGs) produced via melt electrowriting (MEW) [0.03%]
用于小直径组织工程血管移植物的高度顺应性仿生支架的熔融电写法制造技术
Angus Weekes,Gabrielle Wehr,Nigel Pinto et al.
Angus Weekes et al.
Biofabrication approaches toward the development of tissue-engineered vascular grafts (TEVGs) have been widely investigated. However, successful translation has been limited to large diameter applications, with small diameter grafts frequen...
Effects of weaving parameters on the properties of completely biological tissue-engineered vascular grafts [0.03%]
编织参数对全生物型组织工程血管性能的影响
Gaëtan Roudier,Marie Hourques,Nicolas Da Silva et al.
Gaëtan Roudier et al.
Tissue-Engineered Vascular Grafts (TEVGs) made of human textiles have been recently introduced and offer remarkable biocompatibility as well as tunable mechanical properties. The approach combines the use of Cell-Assembled extracellular Mat...
Stress-free cell aggregation by using the CEPT cocktail enhances embryoid body and organoid fitness [0.03%]
无压力的细胞聚集通过使用CEPT鸡尾酒提高类胚胎体和器官体的健康度
Seungmi Ryu,Claire Weber,Pei-Hsuan Chu et al.
Seungmi Ryu et al.
Embryoid bodies (EBs) and self-organizing organoids derived from human pluripotent stem cells (hPSCs) recapitulate tissue development in a dish and hold great promise for disease modeling and drug development. However, current protocols are...
Modular 3D printed platform for fluidically connected human brain organoid culture [0.03%]
模块化三维打印平台在人脑类器官培养中的应用
Babak Rezaei,Jessica Giacomoni,Fredrik Nilsson et al.
Babak Rezaei et al.
Brain organoid technology has transformed both basic and applied biomedical research and paved the way for novel insights into developmental processes and disease states of the human brain. While the use of brain organoids has been rapidly ...
Synergistic coupling between 3D bioprinting and vascularization strategies [0.03%]
基于3D生物打印的血管化策略及其协同作用
Miji Yeo,Anwita Sarkar,Yogendra Pratap Singh et al.
Miji Yeo et al.
Three-dimensional (3D) bioprinting offers promising solutions to the complex challenge of vascularization in biofabrication, thereby enhancing the prospects for clinical translation of engineered tissues and organs. While existing reviews h...