Biofabrication of biomimetic undulating microtopography at the dermal-epidermal junction and its effects on the growth and differentiation of epidermal cells [0.03%]
仿生波状微结构在真皮表皮交界处的生物制造及其对表皮细胞增殖和分化的影响
Chuang Gao,Chunxiang Lu,Huazhen Liu et al.
Chuang Gao et al.
The undulating microtopography located at the junction of the dermis and epidermis of the native skin is called rete ridges (RRs), which plays an important role in enhancing keratinocyte function, improving skin structure and stability, and...
BMP-2-immobilized PCL 3D printing scaffold with a leaf-stacked structure as a physically and biologically activated bone graft [0.03%]
具有叶叠结构的BMP-2固定的PCL 3D打印支架作为物理和生物激活骨移植的应用研究
Min Ji Kim,Jin-Ho Park,Ji Min Seok et al.
Min Ji Kim et al.
Although three-dimensional (3D) printing techniques are used to mimic macro- and micro-structures as well as multi-structural human tissues in tissue engineering, efficient target tissue regeneration requires bioactive 3D printing scaffolds...
Co-axial hydrogel spinning for facile biofabrication of prostate cancer-like 3D models [0.03%]
同轴水凝胶纺丝便于制造类似前列腺癌的3D模型
Carlos F Guimarães,Shiqin Liu,Jie Wang et al.
Carlos F Guimarães et al.
Glandular cancers are amongst the most prevalent types of cancer, which can develop in many different organs, presenting challenges in their detection as well as high treatment variability and failure rates. For that purpose, anticancer dru...
Artificial tumor matrices and bioengineered tools for tumoroid generation [0.03%]
人工肿瘤基质及类肿瘤生成的生物工程工具
Yung-Chiang Liu,Ping Chen,Ray Chang et al.
Yung-Chiang Liu et al.
The tumor microenvironment (TME) is critical for tumor growth and metastasis. The TME contains cancer-associated cells, tumor matrix, and tumor secretory factors. The fabrication of artificial tumors, so-called tumoroids, is of great signif...
Directing ligament-mimetic bi-directional cell organization in scaffolds through zone-specific microarchitecture for ligament tissue engineering [0.03%]
通过区域特定的微观架构指导支架中仿韧带双向细胞组织化以进行韧带组织工程
M Sriram,Smriti Priya,Aman Mahajan et al.
M Sriram et al.
Ligament tissues exhibit zone-specific anisotropic cell organization. The cells in ligament-proper are longitudinally oriented, whereas, the cells in epiligament are circumferentially oriented. Therefore, scaffolds developed to regenerate l...
Current advances in engineering meniscal tissues: insights into 3D printing, injectable hydrogels and physical stimulation based strategies [0.03%]
工程半月板组织的最新进展：对3D打印、可注射水凝胶和物理刺激策略的见解
Ashutosh Bandyopadhyay,Baishali Ghibhela,Biman B Mandal
Ashutosh Bandyopadhyay
The knee meniscus is the cushioning fibro-cartilage tissue present in between the femoral condyles and tibial plateau of the knee joint. It is largely avascular in nature and suffers from a wide range of tears and injuries caused by acciden...
Multilayer nanodrug delivery system with spatiotemporal drug release improves tumor microenvironment for synergistic anticancer therapy [0.03%]
具有时空药物释放的多层纳米药物传输系统优化肿瘤微环境以产生协同抗癌疗效
Jiahui Cai,Yibo Yang,Jia Zhang et al.
Jiahui Cai et al.
The inflammatory response is one of the general symptoms that accompany tumorigenesis, the pro-inflammatory factors cyclooxygenase-2 (COX-2) and COX-2-derived prostaglandin-2 (PGE-2) in the inflammatory environment surrounding tumors posses...
A microscale 3D organ on a chip for recapitulating reciprocal neuroendocrine crosstalk between the hypothalamus and the pituitary gland [0.03%]
用于模拟下丘脑和垂体腺之间相互神经内分泌串扰的微尺度3D器官芯片
Se-Ra Park,Myung Geun Kook,Soo-Rim Kim et al.
Se-Ra Park et al.
Conventional 2D or even recently developed 3Din vitroculture models for hypothalamus and pituitary gland cannot successfully recapitulate reciprocal neuroendocrine communications between these two pivotal neuroendocrine tissues known to pla...
Three dimensional (bio)printing of blood vessels: from vascularized tissues to functional arteries [0.03%]
血管的三维（生物）打印：从血管化组织到有功能的动脉
Shubham Makode,Satyajit Maurya,Seyed A Niknam et al.
Shubham Makode et al.
Tissue engineering has emerged as a strategy for producing functional tissues and organs to treat diseases and injuries. Many chronic conditions directly or indirectly affect normal blood vessel functioning, necessary for material exchange ...
Hydrodynamic shear stress' impact on mammalian cell properties and its applications in 3D bioprinting [0.03%]
流体剪切应力对哺乳动物细胞特性的影响及其在三维生物打印中的应用
Yani Zhang,Aidan O&#x;Mahony,Yong He et al.
Yani Zhang et al.
As an effective cell assembly method, three-dimensional bioprinting has been widely used in building organ models and tissue repair over the past decade. However, different shear stresses induced throughout the entire printing process can c...