Antibacterial, ROS scavenging and angiogenesis promoting ϵ-Polylysine/gelatin based hydrogel containing CTLP to regulate macrophages for pressure ulcer healing [0.03%]
含有CTLP的抗细菌、ROS清除和促血管生成的ε-聚赖氨酸/明胶基水凝胶通过调节巨噬细胞促进压疮愈合
PinLi Lin,Xiaona Tang,Jintao Zhong et al.
PinLi Lin et al.
Pressure ulcers (PUs) have emerged as a substantial burden on individuals and society. The introduction of innovative dressings that facilitate the healing of pressure ulcer wounds represents a cost-effective alternative for treatment. In t...
Decellularized tissue exhibits large differences of extracellular matrix properties dependent on decellularization method: novel insights from a standardized characterization on skeletal muscle [0.03%]
脱细胞组织表现出大的细胞外基质属性差异依赖于脱细胞方法：来自骨骼肌的标准化特征的新见解
Lisanne Terrie,Charlot Philips,Ewout Muylle et al.
Lisanne Terrie et al.
Decellularized matrices are an attractive choice of scaffold in regenerative medicine as they can provide the necessary extracellular matrix (ECM) components, signals and mechanical properties. Various detergent-based protocols have already...
3D bioprinting of mouse pre-osteoblasts and human MSCs using bioinks consisting of gelatin and decellularized bone particles [0.03%]
利用由明胶和去细胞骨颗粒组成的生物墨水3D打印小鼠前成骨细胞和人MSCs
Aylin Kara Özenler,Thomas Distler,Ashwini Rahul Akkineni et al.
Aylin Kara Özenler et al.
One of the key challenges in biofabrication applications is to obtain bioinks that provide a balance between printability, shape fidelity, cell viability, and tissue maturation. Decellularization methods allow the extraction of natural extr...
A long-term storable gel-laden chip composite built in a multi-well plate enabling in situ cell encapsulation for high-throughput liver model [0.03%]
一种长期储存的水凝胶芯片复合材料，在多孔板中实现原位细胞包封，用于高通量肝脏模型构建
Min Kyeong Kim,Jubin Park,Sungho Tak et al.
Min Kyeong Kim et al.
Hydrogels are widely used as scaffold materials for constructingin vitrothree-dimensional microphysiological systems. However, their high sensitivity to various external cues hinders the development of hydrogel-laden, microscale, and high-t...
Fabrication of gradient hydrogels using a thermophoretic approach in microfluidics [0.03%]
利用微流控中的热泳方法制造梯度水凝胶
Alexandros Kosmidis Papadimitriou,Shin Wei Chong,Yi Shen et al.
Alexandros Kosmidis Papadimitriou et al.
The extracellular matrix presents spatially varying physical cues that can influence cell behavior in many processes. Physical gradients within hydrogels that mimic the heterogenous mechanical microenvironment are useful to study the impact...
3D modeling of normal skin and cutaneous squamous cell carcinoma. A comparative study in 2D cultures, spheroids, and 3D bioprinted systems [0.03%]
正常皮肤和皮肤鳞状细胞癌的3D建模。二维培养，类器官和3D生物打印系统的比较研究
Agata Kurzyk,Anna Szumera-Ciećkiewicz,Joanna Miłoszewska et al.
Agata Kurzyk et al.
The current cancer research and drug testing are primarily based on 2D cell cultures and animal models. However, these methods have limitations and yield distinct drug response patterns. This study addressed this gap by developing an innova...
A well plate-based GelMA photo-crosslinking system with tunable hydrogel mechanical properties to regulate the PTH-mediated osteogenic fate [0.03%]
基于 wells 板的 GelMA 光交联系统通过调节可控水凝胶机械性能调控PTH介导的成骨命运
Kyurim Paek,Sangwook Woo,Seung Jae Song et al.
Kyurim Paek et al.
Versatile and efficient regulation of the mechanical properties of the extracellular matrix is crucial not only for understanding the dynamic changes in biological systems, but also for obtaining precise and effective cellular responses in ...
Bioassembly of hemoglobin-loaded photopolymerizable spheroids alleviates hypoxia-induced cell death [0.03%]
负载血红蛋白的光聚球体的生物组装可缓解缺氧诱导的细胞死亡
Axel E Norberg,Ezgi Bakirci,Khoon S Lim et al.
Axel E Norberg et al.
The delivery of oxygen within tissue engineered constructs is essential for cell survivability; however, achieving this within larger biofabricated constructs poses a significant challenge. Efforts to overcome this limitation often involve ...
Analysis of bioprinting strategies for skin diseases and injuries through structural and temporal dynamics: historical perspectives, research hotspots, and emerging trends [0.03%]
通过结构和时间动力学分析皮肤疾病和损伤的生物打印策略：历史视角、研究热点及新兴趋势
Fei Teng,Wei Wang,Zhi-Qiang Wang et al.
Fei Teng et al.
This study endeavors to investigate the progression, research focal points, and budding trends in the realm of skin bioprinting over the past decade from a structural and temporal dynamics standpoint. Scholarly articles on skin bioprinting ...
UV laser-processed microstructure for building biohybrid actuators with anisotropic movement [0.03%]
用于构建具有各向异性运动的生物杂化执行器的紫外激光处理微结构
Hiroaki Mita,Yosuke Mizuno,Hiroto Tanaka et al.
Hiroaki Mita et al.
Fabrication of a biohybrid actuator requires muscle cells anisotropically aligned in a line, curve, or combination of lines and curves (similar to the microstructure of living muscle tissue) to replicate lifelike movements, in addition to c...