Fixation method of a single muscle fiber by magnetic force for stretching, transportation, and evaluation of mechanical properties [0.03%]
磁力固定单根肌纤维的拉伸、传输及机械性能检测方法
Zhaoyu Wang,Taisuke Masuda,Fumihito Arai
Zhaoyu Wang
Engineered muscle fibers are attracting interest in bio-actuator research as they can contribute to the fabrication of actuators with a high power/size ratio for micro-robots. These fibers require to be stretched during culture for function...
Engineering pre-vascularized 3D tissue and rapid vascular integration with host blood vessels via co-cultured spheroids-laden hydrogel [0.03%]
通过共培养的类器官水凝胶工程化预血管化的3D组织及快速与宿主血管整合
Hyunseok Kwon,Sangmin Lee,Hayeon Byun et al.
Hyunseok Kwon et al.
Recent advances in regenerative medicine and tissue engineering have enabled the biofabrication of three-dimensional (3D) tissue analogues with the potential for use in transplants and disease modeling. However, the practical use of these b...
Sheet-based extrusion bioprinting: a new multi-material paradigm providing mid-extrusion micropatterning control for microvascular applications [0.03%]
基于片的挤出生物打印技术:为微血管应用提供中途微观图案控制的新多材料模式
Ryan Hooper,Caleb Cummings,Anna Beck et al.
Ryan Hooper et al.
As bioprinting advances into clinical relevance with patient-specific tissue and organ constructs, it must be capable of multi-material fabrication at high resolutions to accurately mimick the complex tissue structures found in the body. On...
Surface slicing and toolpath planning for in-situ bioprinting of skin implants [0.03%]
皮肤植入物原位生物打印的表面切片和刀具路径规划
Muhammad Salman Chaudhry,Aleksander Czekanski
Muhammad Salman Chaudhry
Bioprinting has emerged as a successful method for fabricating engineered tissue implants, offering great potential for wound healing applications. This study focuses on an advanced surface-based slicing approach aimed at designing a skin i...
Using a micro-device with a deformable ceiling to probe stiffness heterogeneities within 3D cell aggregates [0.03%]
使用具有可变形天花板的微设备探究三维细胞聚集体内的刚性不均一性
Shreyansh Jain,Hiba Belkadi,Arthur Michaut et al.
Shreyansh Jain et al.
Recent advances in the field of mechanobiology have led to the development of methods to characterise single-cell or monolayer mechanical properties and link them to their functional behaviour. However, there remains a strong need to establ...
Printing GelMA bioinks: a strategy for building in vitro model to study nanoparticle-based minocycline release and cellular protection under oxidative stress [0.03%]
印刷GelMA生物墨水:构建体外模型研究基于纳米粒子的米诺环素释放及氧化应激下细胞保护的方法
Zhouquan Fu,Nan Hai,Yinghui Zhong et al.
Zhouquan Fu et al.
Owing to its thermoresponsive and photocrosslinking characteristics, gelatin methacryloyl (GelMA)-based biomaterials have gained widespread usage as a novel and promising bioink for three-dimensional bioprinting and diverse biomedical appli...
Mengchao Yan,Jia Yao,Ye Xie et al.
Mengchao Yan et al.
Stem cell therapy, achieved using mesenchymal stem cells (MSCs), has been highlighted for the treatment of liver fibrosis. Infusion into the circulatory system is a traditional application of MSCs; however, this approach is limited by pheno...
Generating human skeletal myoblast spheroids for vascular myogenic tissue engineering [0.03%]
用于血管平滑肌组织工程的人类骨骼肌肌母细胞球体的生成
Mendy Minne,Lisanne Terrie,Rebecca Wüst et al.
Mendy Minne et al.
Engineered myogenic microtissues derived from human skeletal myoblasts offer unique opportunities for varying skeletal muscle tissue engineering applications, such asin vitrodrug-testing and disease modelling. However, more complex models r...
Microfluidic-based preparation of artificial antigen-presenting gel droplets for integrated and minimalistic adoptive cell therapy strategies [0.03%]
基于微流体技术制备人工抗原递呈凝胶液滴用于整合和极简过继细胞治疗策略
Yishen Tian,Wei Chen,Guangshi Du et al.
Yishen Tian et al.
Adoptive T-cell transfer for cancer therapy is limited by the inefficiency ofin vitroT-cell expansion and the ability ofin vivoT-cells to infiltrate tumors. The construction of multifunctional artificial antigen-presenting cells is a promis...
Renal proximal tubule-on-a-chip in PDMS: fabrication, functionalization, and RPTEC:HUVEC co-culture evaluation [0.03%]
聚二甲基硅氧烷中芯片上的肾近端小管:制造,功能化和RPTEC:HUVEC共培养评价
Ana Paula Pereira Guimaraes,Italo Rodrigo Calori,Roberta Sessa Stilhano et al.
Ana Paula Pereira Guimaraes et al.
'On-a-chip' technology advances the development of physiologically relevant organ-mimicking architecture by integrating human cells into three-dimensional microfluidic devices. This method also establishes discrete functional units, facilit...