Histo-pillar strip for optimal histogel block construction and biomarker analysis in 3D-lung cancer patient-derived organoids [0.03%]
用于3D肺癌患者来源类器官的组织胶块构建和生物标志物分析的最佳 histo-pillar 条-strip
Sang-Yun Lee,Eunyoung Lee,Ji-O Ryu et al.
Sang-Yun Lee et al.
This study proposed an optimized histogel construction method for histological analysis by applying lung cancer patient-derived organoids (PDOs) to the developed histo-pillar strip. Previously, there is the cultured PDOs damage problem duri...
Robust and customizable spheroid culture system for regenerative medicine [0.03%]
一种用于再生医学的稳健且可定制的类球体培养系统
Kyoung Hwan Park,Thuy Trang Truong,Jae-Hyun Park et al.
Kyoung Hwan Park et al.
Three-dimensional cell spheroids show promise for the reconstruction of native tissues. Herein, we report a sophisticated, uniform, and highly reproducible spheroid culture system for tissue reconstruction. A mesh-integrated culture system ...
Formation and culture of cell spheroids by using magnetic nanostructures resembling a crown of thorns [0.03%]
使用类似荆棘王冠的磁性纳米结构形成和培养细胞球体
Shijiao Li,Jingjiang Qiu,Zhongwei Guo et al.
Shijiao Li et al.
In contrast to traditional two-dimensional cell-culture conditions, three-dimensional (3D) cell-culture models closely mimic complexin vivoconditions. However, constructing 3D cell culture models still faces challenges. In this paper, by us...
A nasal airway-on-chip model to evaluate airflow pre-conditioning during epithelial cell maturation at the air-liquid interface [0.03%]
一种鼻腔空气通道芯片模型，用于评估上皮细胞在气液界面成熟过程中的气流预处理效应
Amanda C Walls,Manon van Vegchel,Abigail Lakey et al.
Amanda C Walls et al.
The function of a well-differentiated nasal epithelium is largely affected by airflow-induced wall shear stress, yet fewin vitromodels recapitulate this dynamic condition. Models which do expose cells to airflow exclusively initiate flow af...
A novel membrane-on-chip guides morphogenesis for the reconstruction of the intestinal crypt-villus axis [0.03%]
一种新型芯片上的膜指导形态发生以重建肠隐窝-绒毛轴
Sara Sibilio,Raffaele Mennella,Vincenza De Gregorio et al.
Sara Sibilio et al.
Reconstructing the microscale villous organisation and functionality of the small intestine is essential for developingin vitroplatforms tailored for absorption studies as well as for investigating intestinal morphogenesis in development an...
Fabrication of heterocellular spheroids with controllable core-shell structure using inertial focusing effect for scaffold-free 3D cell culture models [0.03%]
利用惯性聚焦效应制造具有可控核壳结构的异种细胞球体用于无支架三维细胞培养模型
Tan Tang,Pengfei Zhang,Qiuting Zhang et al.
Tan Tang et al.
Three-dimensional (3D) cell culture models capable of emulating the biological functions of natural tissues are pivotal in tissue engineering and regenerative medicine. Despite progress, the fabrication ofin vitroheterocellular models that ...
Fabricating vascularized, anatomically accurate bone grafts using 3D bioprinted sectional bone modules, in-situ angiogenesis, BMP-2 controlled release, and bioassembly [0.03%]
基于3D生物打印骨模块的血管化及解剖型骨移植的构建
Brian E Grottkau,Zhixin Hui,Chongzhao Ran et al.
Brian E Grottkau et al.
Bone grafting is the most common treatment for repairing bone defects. However, current bone grafting methods have several drawbacks. Bone tissue engineering emerges as a promising solution to these problems. An ideal engineered bone graft ...
A practical machine learning approach for predicting the quality of 3D (bio)printed scaffolds [0.03%]
一种实用的机器学习方法预测三维（生物）打印支架的质量
Saeed Rafieyan,Elham Ansari,Ebrahim Vasheghani-Farahani
Saeed Rafieyan
3D (Bio)printing is a highly effective method for fabricating tissue engineering scaffolds, renowned for their exceptional precision and control. Artificial intelligence (AI) has become a crucial technology in this field, capable of learnin...
Direct 3D printing of freeform anisotropic bioactive structure based on shear-oriented ink system [0.03%]
基于剪切取向墨水体系的自由成型生物活性结构的直接3D打印技术
Chenhui Yuan,Jinhong Jiang,Xinyu Zhang et al.
Chenhui Yuan et al.
Various anisotropic tissue structures exist in organisms, including muscle tissue, skin tissue, and nerve tissue. Replicating anisotropic tissue structuresin vitrohas posed a significant challenge. Three-dimensional (3D) printing technology...
Riboflavin overproduction from diverse feedstocks with engineered Corynebacterium glutamicum [0.03%]
利用工程化谷氨酸棒杆菌从不同原料中大量生产核黄素
Fernando Pérez-García,Luciana Fernandes Brito,Thea Isabel Bakken et al.
Fernando Pérez-García et al.
Riboflavin overproduction byCorynebacterium glutamicumwas achieved by screening synthetic operons, enabling fine-tuned expression of the riboflavin biosynthetic genesribGCAH.The synthetic operons were designed by means of predicted translat...