Droplet-based microfluidics for engineering shape-controlled hydrogels with stiffness gradient [0.03%]
基于微滴的微流控技术合成形状可控且具有硬度梯度的水凝胶
Bram G Soliman,Ian L Chin,Yiwei Li et al.
Bram G Soliman et al.
Current biofabrication strategies are limited in their ability to replicate native shape-to-function relationships, that are dependent on adequate biomimicry of macroscale shape as well as size and microscale spatial heterogeneity, within c...
Multicellular 3D bioprinted human gallbladder carcinoma for in vitro mimicry of tumor microenvironment and intratumoral heterogeneity [0.03%]
体外模拟肿瘤微环境和瘤内异质性的多细胞三维生物打印人类胆囊癌模型
Yukai Jin,Jiangang Zhang,Jiali Xing et al.
Yukai Jin et al.
Gallbladder carcinoma (GBC) is a malignant hepatobiliary cancer characterized by an intricate tumor microenvironments (TME) and heterogeneity. The traditional GBC 2D culture models cannot faithfully recapitulate the characteristics of the T...
3D in vitro modeling of the exocrine pancreatic unit using tomographic volumetric bioprinting [0.03%]
利用层析体积生物打印技术使用三维体外胰腺外分泌单元建模
Viola Sgarminato,Jorge Madrid-Wolff,Antoine Boniface et al.
Viola Sgarminato et al.
Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer, a leading cause of cancer-related deaths globally. Initial lesions of PDAC develop within the exocrine pancreas' functional units, with tumor progression ...
Sunghan Lee,Young Gyun Kim,Hyo-Il Jung et al.
Sunghan Lee et al.
Osteoporosis is the most common bone disorder, which is a highly dangerous condition that can promote bone metastases. As the current treatment for osteoporosis involves long-term medication therapy and a cure for bone metastasis is not kno...
Implementing microfluidic flow device model in utilizing dural substitutes as pulp capping materials for vital pulp therapy [0.03%]
利用微流控流动装置模型评估用于活髓治疗的硬组织替代品作为盖髓剂的效果
Min-Yong Lee,Hi-Won Yoon,Sun-Il Kim et al.
Min-Yong Lee et al.
Vital pulp therapy (VPT) has gained prominence with the increasing trends towards conservative dental treatment with specific indications for preserving tooth vitality by selectively removing the inflamed tissue instead of the entire dental...
Highly conductive, stretchable, and biocompatible graphene oxide biocomposite hydrogel for advanced tissue engineering [0.03%]
一种用于先进组织工程的高度导电、可拉伸和生物相容的石墨烯氧化物生物复合水凝胶
Young Jin Lee,Olatunji Ajiteru,Ji Seung Lee et al.
Young Jin Lee et al.
The importance of hydrogels in tissue engineering cannot be overemphasized due to their resemblance to the native extracellular matrix. However, natural hydrogels with satisfactory biocompatibility exhibit poor mechanical behavior, which ha...
Exploring bio-nanomaterials as antibiotic allies to combat antimicrobial resistance [0.03%]
探究生物纳米材料作为抗生素盟友以对抗微生物抗药性
Bindiya Barsola,Shivani Saklani,Diksha Pathania et al.
Bindiya Barsola et al.
Antimicrobial resistance (AMR) poses an emergent threat to global health due to antibiotic abuse, overuse and misuse, necessitating urgent innovative and sustainable solutions. The utilization of bio-nanomaterials as antibiotic allies is a ...
Efficient fabrication of 3D bioprinted functional sensory neurons using an inducible Neurogenin-2 human pluripotent stem cell line [0.03%]
高效制作功能感官神经元的3D生物墨水细胞系诱导制备神经源性基因Ngneurogenin-2的人类多能干细胞系）
Mitchell St Clair-Glover,Rocio K Finol-Urdaneta,Marnie Maddock et al.
Mitchell St Clair-Glover et al.
Three-dimensional (3D) tissue models have gained recognition for their improved ability to mimic the native cell microenvironment compared to traditional two-dimensional models. This progress has been driven by advances in tissue-engineerin...
Md Mehedee Hasan,Ashfaq Ahmad,Mst Zobaida Akter et al.
Md Mehedee Hasan et al.
Three-dimensional (3D) bioprinting has revolutionized tissue engineering by enabling the fabrication of complex and functional human tissues and organs. An essential component of successful 3D bioprinting is the selection of an appropriate ...
In vitro osteogenesis of hMSCs on collagen membranes embedded within LEGO®-inspired 3D printed PCL constructs for mandibular bone repair [0.03%]
基于乐高理念的3D打印PCL结构中嵌入胶原膜的体外成骨研究用于下颌骨修复
Daphne van der Heide,Luan Phelipe Hatt,Sylvie Wirth et al.
Daphne van der Heide et al.
The field of bone tissue engineering aims to develop an effective and aesthetical bone graft substitute capable of repairing large mandibular defects. However, graft failure resulting from necrosis and insufficient integration with native t...