A capsule-based scaffold incorporating decellularized extracellular matrix and curcumin for islet beta cell therapy in type 1 diabetes mellitus [0.03%]
一种包含脱细胞基质和姜黄素的囊泡支架在1型糖尿病自体胰岛移植中的应用研究
Hailin Ma,Jie Xu,Huan Fang et al.
Hailin Ma et al.
The transplantation of islet beta cells offers an alternative to heterotopic islet transplantation for treating type 1 diabetes mellitus (T1DM). However, the use of systemic immunosuppressive drugs in islet transplantation poses significant...
Endothelial extracellular vesicles enhance vascular self-assembly in engineered human cardiac tissues [0.03%]
工程化的人类心脏组织中的内皮细胞外囊泡可增强血管自我组装功能
Karl T Wagner,Rick X Z Lu,Shira Landau et al.
Karl T Wagner et al.
The fabrication of complex and stable vasculature in engineered cardiac tissues represents a significant hurdle towards building physiologically relevant models of the heart. Here, we implemented a 3D model of cardiac vasculogenesis, incorp...
Complex in vitro models positioned for impact to drug testing in pharma: a review [0.03%]
体外复杂模型在药物检测中的作用：综述式的评论论文
Serah Kang,Eugene C Chen,Helen Cifuentes et al.
Serah Kang et al.
Recent years have seen the creation and popularization of various complexin vitromodels (CIVMs), such as organoids and organs-on-chip, as a technology with the potential to reduce animal usage in pharma while also enhancing our ability to c...
High-yield extracellular vesicle production from HEK293T cells encapsulated in 3D auxetic scaffolds with cyclic mechanical stimulation for effective drug carrier systems [0.03%]
用于有效药物递送系统的三维辅助支架中包封的HEK293T细胞在周期性机械刺激下的高产外泌体生产
Yi-Wen Chen,Yen-Hong Lin,Chia-Che Ho et al.
Yi-Wen Chen et al.
Extracellular vesicles (EVs) show promise in drug loading and delivery for medical applications. However, the lack of scalable manufacturing processes hinders the generation of clinically suitable quantities, thereby impeding the translatio...
Constraint based Bayesian optimization of bioink precursor: a machine learning framework [0.03%]
基于约束的生物墨水前体贝叶斯优化：一种机器学习框架
Yihao Xu,Rokeya Sarah,Ahasan Habib et al.
Yihao Xu et al.
Current research practice for optimizing bioink involves exhaustive experimentation with multi-material composition for determining the printability, shape fidelity and biocompatibility. Predicting bioink properties can be beneficial to the...
In vitro three-dimensional volumetric printing of vitreous body models using decellularized extracellular matrix bioink [0.03%]
基于脱细胞基质生物墨水的玻璃体模型的三维体积打印技术（体外）
Jeong Sik Kong,Joeng Ju Kim,Leonardo Riva et al.
Jeong Sik Kong et al.
Hyalocytes, which are considered to originate from the monocyte/macrophage lineage, play active roles in vitreous collagen and hyaluronic acid synthesis. Obtaining a hyalocyte-compatible bioink during the 3D bioprinting of eye models is cha...
Laser-assisted bioprinting of targeted cartilaginous spheroids for high density bottom-up tissue engineering [0.03%]
激光辅助生物打印靶向软骨球形体用于高密度自下而上型组织工程
Gabriella Nilsson Hall,Yuchao Fan,Bertrand Viellerobe et al.
Gabriella Nilsson Hall et al.
Multicellular spheroids such as microtissues and organoids have demonstrated great potential for tissue engineering applications in recent years as these 3D cellular units enable improved cell-cell and cell-matrix interactions. Current biop...
Vascular tissues bioprinted with smooth muscle cell-only bioinks in support baths mimic features of native coronary arteries [0.03%]
仅含平滑肌细胞的生物墨水在支持浴液中进行血管组织3D打印类仿生冠状动脉特征
Andre E Figueroa-Milla,William DeMaria,Derrick Wells et al.
Andre E Figueroa-Milla et al.
This study explores the bioprinting of a smooth muscle cell-only bioink into ionically crosslinked oxidized methacrylated alginate (OMA) microgel baths to create self-supporting vascular tissues. The impact of OMA microgel support bath meth...
Effect of viscosity of gelatin methacryloyl-based bioinks on bone cells [0.03%]
凝胶状明胶丙烯酸酯基生物墨水的粘度对骨细胞的影响
Ahmad Rashad,Alejandro Gomez,Ankit Gangrade et al.
Ahmad Rashad et al.
The viscosity of gelatin methacryloyl (GelMA)-based bioinks generates shear stresses throughout the printing process that can affect cell integrity, reduce cell viability, cause morphological changes, and alter cell functionality. This stud...
Microneedle system for tissue engineering and regenerative medicines: a smart and efficient therapeutic approach [0.03%]
用于组织工程和再生医学的微针系统：一种智能且高效的治疗策略
Muhammad Umar Aslam Khan,Muhammad Azhar Aslam,Mohd Faizal Bin Abdullah et al.
Muhammad Umar Aslam Khan et al.
The global demand for an enhanced quality of life and extended lifespan has driven significant advancements in tissue engineering and regenerative medicine. These fields utilize a range of interdisciplinary theories and techniques to repair...