Pharmacy 3D printing [0.03%]
制药业3D打印技术
Jessica T Y Cheng,Edwin C K Tan,Lifeng Kang
Jessica T Y Cheng
A significant limitation of the 'one size fits all' medication approach is the lack of consideration for special population groups. 3D printing technology has revolutionised the landscape of pharmaceuticals and pharmacy practice, playing an...
RCAN1.4 regulates tumor cell engraftment and invasion in a thyroid cancer to lung metastasis-on-a-chip microphysiological system [0.03%]
RCAN1.4在甲状腺癌肺转移芯片生理系统中的肿瘤细胞植入和侵袭的调节作用
Kylie G Nairon,Akanksha Nigam,Tilak Khanal et al.
Kylie G Nairon et al.
Progressive metastasis is the primary cause of cancer-related deaths. It has been recognized that many cancers are characterized by long periods of stability followed by subsequent progression. Genes termed metastasis progression suppressor...
Chlorella-enriched hydrogels protect against myocardial damage and reactive oxygen species production in an in vitro ischemia/reperfusion model using cardiac spheroids [0.03%]
螺旋藻富集水凝胶通过在体外心脏类器官缺血/再灌注模型中减少活性氧产生来预防心肌损伤
Martine Tarsitano,Clara Liu Chung Ming,Lucia Bennar et al.
Martine Tarsitano et al.
Microalgae have emerged as promising photosynthetic microorganisms for biofabricating advanced tissue constructs, with improved oxygenation and reduced reactive oxygen species (ROS) production. However, their use in the engineering of human...
A microvascularized in vitro liver model for disease modeling and drug discovery [0.03%]
一种用于疾病建模和药物发现的体外肝微血管模型
Flavio Bonanini,Roelof Dinkelberg,Manuel Caro Torregrosa et al.
Flavio Bonanini et al.
Drug discovery for complex liver diseases faces alarming attrition rates. The lack of non-clinical models that recapitulate key aspects of liver (patho)-physiology is likely contributing to the inefficiency of developing effective treatment...
A compartmentalized microfluidic platform to investigate immune cells cross-talk in rheumatoid arthritis [0.03%]
一个隔舱式微流控平台用于探究类风湿性关节炎免疫细胞交叉谈话现象
Cecilia Palma,Bianca Aterini,Erika Ferrari et al.
Cecilia Palma et al.
The dysregulation of the immune system plays a crucial role in the pathogenesis of manyfold diseases, among which we find rheumatoid arthritis (RA), an autoimmune disease characterized by chronic inflammation in synovial joints, leading to ...
On-chip human lymph node stromal network for evaluating dendritic cell and T-cell trafficking [0.03%]
芯片上的人类淋巴结基质网络，用于评估树突细胞和T细胞的转运
Brian J Kwee,Mona Mansouri,Adovi Akue et al.
Brian J Kwee et al.
The lymph node paracortex, also known as the T-cell zone, consists of a network of fibroblastic reticular cells (FRCs) that secrete chemokines to induce T-cell and dendritic cell (DC) trafficking into the paracortex. To model the lymph node...
3D engineering of diseased blood vessels for integrative in vitro-in silico mechanobiology study [0.03%]
用于整体化体外-体内心脏力学生物学研究的疾病血管三维工程学
Wonbin Park,Jae-Seong Lee,Min-Ju Choi et al.
Wonbin Park et al.
Vascular diseases are complex conditions orchestrated by multiple factors, including cellular components, biochemical stimuli, and mechanical forces. Despite the advancement of numerous therapeutic approaches, the global mortality associate...
Calcium phosphate complex of recombinant human thrombomodulin promote bone formation in interbody fusion [0.03%]
人重组血栓调节蛋白磷酸钙复合物促进椎间融合骨形成
Cheng-Li Lin,Yu-Wei Chen,Cheng-Hsiang Kuo et al.
Cheng-Li Lin et al.
Interbody fusion is an orthopedic surgical procedure to connect two adjacent vertebrae in patients suffering from spinal disc disease. The combination of synthetic bone grafts with protein-based drugs is an intriguing approach to stimulate ...
An innovative 4D printing approach for fabrication of anisotropic collagen scaffolds [0.03%]
一种用于制备各向异性胶原蛋白支架的创新性4d打印方法研究
Nashaita Y Patrawalla,Karly Liebendorfer,Vipuil Kishore
Nashaita Y Patrawalla
Collagen anisotropy is known to provide the essential topographical cues to guide tissue-specific cell function. Recent work has shown that extrusion-based printing using collagenous inks yield 3D scaffolds with high geometric precision and...
Biofabrication & cryopreservation of tissue engineered constructs for on-demand applications [0.03%]
用于按需应用的组织工程构建体的生物制造与冷冻保存
Harshavardhan Budharaju,Dhakshinamoorthy Sundaramurthi,Swaminathan Sethuraman
Harshavardhan Budharaju
Tissue engineered constructs prepared using conventional scaffold-based approaches have the potential to repair or regenerate damaged tissues and organs. Various scaffold fabrication strategies such as electrospinning, solvent casting, part...