Leanne M Friedrich,Ross T Gunther
Leanne M Friedrich
In embedded 3D printing (EMB3D), a nozzle extrudes continuous filaments inside of a viscoelastic support bath. Compared to other extrusion processes, EMB3D enables softer structures and print paths that conform better to the shape of the pa...
Automated production of nerve repair constructs containing endothelial cell tube-like structures [0.03%]
包含内皮细胞管状结构的神经修复构建物的自动化生产
Poppy O Smith,Guanbingxue Huang,Kate Devries et al.
Poppy O Smith et al.
Engineered neural tissue (EngNT) is a stabilised aligned cellular hydrogel that offers a potential alternative to the nerve autograft for the treatment of severe peripheral nerve injury. This work aimed to automate the production of EngNT, ...
CMC/Gel/GO 3D-printed cardiac patches: GO and CMC improve flexibility and promote H9C2 cell proliferation, while EDC/NHS enhances stability [0.03%]
基于CMC、凝胶和GO的三维打印心脏补片及其性能研究
Şule Arıcı,Ali Reza Kamali,Duygu Ege
Şule Arıcı
In this research, carboxymethyl cellulose (CMC)/gelatin (Gel)/graphene oxide (GO)-based scaffolds were produced by using extrusion-based 3D printing for cardiac tissue regeneration. Rheological studies were conducted to evaluate the printab...
A generic cell-based biosensor converts bacterial infection signals into chemoattractants for immune cells [0.03%]
一种通用的基于细胞的生物传感器可将细菌感染信号转化为免疫细胞化学吸引剂
Sushobhan Sarker,Mario Köster,Omkar Desai et al.
Sushobhan Sarker et al.
Bacterial infection is a major challenge to human health. Although various potent antibiotics have emerged in recent decades, current challenges arise from the increasing number of multi-drug-resistant species. Infections associated with im...
Improved visualisation of ACP-engineered osteoblastic spheroids: a comparative study of contrast-enhanced micro-CT and traditional imaging techniques [0.03%]
改良的ACP改性成骨细胞球体可视化方法：对比增强显微CT与传统影像技术的比较研究
Torben Hildebrand,Qianli Ma,Dagnija Loca et al.
Torben Hildebrand et al.
This study investigates osteoblastic cell spheroid cultivation methods, exploring flat-bottom, U-bottom, and rotary flask techniques with and without amorphous calcium phosphate (ACP) supplementation to replicate the 3D bone tissue microenv...
Comparative Study
Biofabrication. 2024 Nov 6;17(1). DOI:10.1088/1758-5090/ad8bf5 2024
3D bioprinted in vitro epilepsy models for pharmacological evaluation in temporal lobe epilepsy [0.03%]
用于颞叶癫痫药理学评估的3D生物打印体外癫痫模型
Wei Chen,Ke Gai,Xiao Luo et al.
Wei Chen et al.
This study introduces a novelin vitromodel for intractable temporal lobe epilepsy (TLE) utilizing 3D bioprinting technology, aiming to replicate the complex neurobiological characteristics of TLE more accurately. Primary neural cell constru...
Fabrication of hierarchically porous trabecular bone replicas via 3D printing with high internal phase emulsions (HIPEs) [0.03%]
基于HIPE的3D打印制备具有层次多孔结构的人工骨小梁结构
Nihan Sengokmen-Ozsoz,Mina Aleemardani,Marco Palanca et al.
Nihan Sengokmen-Ozsoz et al.
Combining emulsion templating with additive manufacturing enables the production of inherently porous scaffolds with multiscale porosity. This approach incorporates interconnected porous materials, providing a structure that supports cell i...
Standalone single- and bi-layered human skin 3D models supported by recombinant silk feature native spatial organization [0.03%]
重组丝素蛋白支持的单层和双层人体皮肤3D模型具有天然的空间组织属性
Savvini Gkouma,Nayanika Bhalla,Solène Frapard et al.
Savvini Gkouma et al.
Physiologically relevant human skin models that include key skin cell types can be used forin vitrodrug testing, skin pathology studies, or clinical applications such as skin grafts. However, there is still no golden standard for such a mod...
Dynamic culture of cerebral organoids using a pillar/perfusion plate for the assessment of developmental neurotoxicity [0.03%]
使用立柱/灌流板动态培养脑类器官以评估发育神经毒性
Prabha Acharya,Sunil Shrestha,Pranav Joshi et al.
Prabha Acharya et al.
Despite the potential toxicity of commercial chemicals to the development of the nervous system (known as developmental neurotoxicity or DNT), conventionalin vitrocell models have primarily been employed for the assessment of acute neuronal...
Micro-thin hydrogel coating integrated in 3D printing for spatiotemporal delivery of bioactive small molecules [0.03%]
一种微薄水凝胶涂层的三维打印集成技术实现生物活性小分子的时空递送
Md Sarker,Soomin Park,Vivek Kumar et al.
Md Sarker et al.
Three-dimensional (3D) printing incorporated with controlled delivery is an effective tool for complex tissue regeneration. Here, we explored a new strategy for spatiotemporal delivery of bioactive cues by establishing a precise-controlled ...