Advancement of 3D biofabrication in repairing and regeneration of cartilage defects [0.03%]
三维生物制造技术在软骨缺损修复与再生中的应用进展
Zenghui Zheng,Dongmei Yu,Haoyu Wang et al.
Zenghui Zheng et al.
Three-dimensional (3D) bioprinting, an additive manufacturing technology, fabricates biomimetic tissues that possess natural structure and function. It involves precise deposition of bioinks, including cells, and bioactive factors, on basis...
Ameliorating macrophage pyroptosis via ANXA1/NLRP3/Caspase-1/GSDMD pathway：Ac2-26/OGP-loaded intelligent hydrogel enhances bone healing in diabetic periodontitis [0.03%]
糖尿病牙周炎中载有Ac2-26/OGP的智能水凝胶通过ANXA1/NLRP3/Caspase-1/GSDMD途径改善巨噬细胞焦亡并促进骨愈合
Ruoyu Li,Wenfeng Li,Yungshan Teng et al.
Ruoyu Li et al.
Craniofacial bone defect healing in periodontitis patients with diabetes background has long been difficult due to increased blood glucose levels which cause overproduction of reactive oxygen species (ROS) and a low pH environment. These co...
Valorization of crop by-products into bio-based dental materials: advancements and prospects [0.03%]
作物副产品的生物基牙科材料化：进展与前景
Marcin Mikulewicz,Katarzyna Chojnacka
Marcin Mikulewicz
The objective of this review is to deepen understanding and emphasize scientific and technological progress in the transformation of crop by-products into bio-based dental materials. Amid heightened environmental sustainability consciousnes...
Systematic development and bioprinting of novel nanostructured multi-material bioinks for bone tissue engineering [0.03%]
用于骨组织工程的新型纳米结构多材料生物墨水的系统开发和生物打印
Jannika T Korkeamäki,Ahmad Rashad,Miina Ojansivu et al.
Jannika T Korkeamäki et al.
A functional bioink with potential in bone tissue engineering must be subjected to critical investigation throughout its intended lifespan. The aim of this study was to develop alginate-gelatin-based (Alg-Gel) multicomponent bioinks systema...
Biofabrication of anisotropic articular cartilage based on decellularized extracellular matrix [0.03%]
基于脱细胞基质的各向异性关节软骨生物制造
Anna Puiggalí-Jou,Isabel Hui,Lucrezia Baldi et al.
Anna Puiggalí-Jou et al.
Tissue-engineered grafts that mimic articular cartilage show promise for treating cartilage injuries. However, engineering cartilage cell-based therapies to match zonal architecture and biochemical composition remains challenging. Decellula...
Lung dECM matrikine-based hydrogel reverses bleomycin-induced pulmonary fibrosis by suppressing M2 macrophage polarization [0.03%]
基于肺dECM基质的水凝胶通过抑制M2型巨噬细胞极化逆转博来霉素诱导的肺纤维化
Xinglong Zhu,Ying Yang,Shengqiang Mao et al.
Xinglong Zhu et al.
Background.Recent studies have shown promising results using decellularized extracellular matrix (dECM) matrikines-based hydrogel as attractive strategies for preventing and alleviating fibrosis.Methods & Results.Porcine lung decellularizat...
An immunocompetent human kidney on-a-chip model to study renal inflammation and immune-mediated injury [0.03%]
一种用于研究肾炎和免疫介导损伤的人类肾脏芯片模型
Linda Gijzen,Marleen Bokkers,Richa Hanamsagar et al.
Linda Gijzen et al.
Kidney damage and dysfunction is an emerging health issue worldwide resulting in high morbidity and mortality rates. Numerous renal diseases are recognized to be driven by the immune system. Despite this recognition, the development of targ...
3D printed PCL-nHAp composite implants for the treatment of segmental bone defects: in vivo application in a rabbit model [0.03%]
基于PCL-nHAp复合材料的3D打印假体治疗骨段缺损：兔模型的体内实验研究
Deniz Başöz,Muhammed İlkay Karaman,Senem Büyüksungur et al.
Deniz Başöz et al.
The management and treatment of long bone defects are challenging clinical problems. In this study, in order to address the need for load bearing segmental defects, 3D printed cylindrical implants of poly(-caprolactone) (PCL) and nanohydrox...
Embedded 3D printing of engineered lung cancer model for assisting fine-needle aspiration biopsy [0.03%]
用于辅助细针穿刺活检的嵌入式3D工程肺癌模型打印技术
Weijian Hua,Cheng Zhang,Lily Raymond et al.
Weijian Hua et al.
Lung cancer is a serious global health issue that requires the development of patient-specific, lung cancer model for surgical planning to train interventionalists and improve the accuracy of biopsies. Although the emergence of three-dimens...
3D printed PGCL@PLA/10CSPL composite scaffolds loaded with fibronectin 1 for intervertebral disc degeneration treatment [0.03%]
负载纤连蛋白1的PGCL@PLA/10CSPL复合支架用于椎间盘退变治疗
Weilin Zhang,Siyuan Chen,Shengbang Huang et al.
Weilin Zhang et al.
Restoration of disc height and biomechanical function is essential for intervertebral disc degeneration (IDD) treatment. Removing abnormal nucleus pulposus (NP) tissue is an important step to facilitate bony fusion during the healing proces...