Application progress of bio-manufacturing technology in kidney organoids [0.03%]
生物制造技术在肾脏类器官制备中应用进展
Runqi Mao,Junming Zhang,Haoxiang Qin et al.
Runqi Mao et al.
Kidney transplantation remains a pivotal treatment modality for kidney disease, yet its progress is significantly hindered by the scarcity of donor kidneys and ethical dilemmas surrounding their procurement. As organoid technology evolves a...
A micro-lung chip with macrophages for targeted anti-fibrotic therapy [0.03%]
带有巨噬细胞的微型肺芯片用于靶向抗纤维化疗法
Jingjing Xia,Ruming Dong,Yongcong Fang et al.
Jingjing Xia et al.
Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease of unknown etiology. Macrophages are implicated in the fibrotic process, but exhibit remarkable plasticity in the activated immune environment in vivo, presenting significant chal...
Purified adipose tissue-derived extracellular vesicles facilitate adipose organoid vascularization through coordinating adipogenesis and angiogenesis [0.03%]
纯化的脂肪组织源性外泌体通过协调脂肪生成和血管生成促进脂肪器官样结构的血管化
Congxiao Zhu,Zonglin Huang,Hongru Zhou et al.
Congxiao Zhu et al.
One of the major challenges in the way of better fabricating vascularized adipose organoids is the destructive effect of adipogenic differentiation on preformed vasculature, which probably stems from the discrepancy between the in vivo phys...
Influence of asymmetric microchannels in the structure and function of engineered neuronal circuits [0.03%]
不对称微通道对工程神经回路的结构和功能的影响
José Mateus,Pedro Melo,Miguel Aroso et al.
José Mateus et al.
Understanding the intricate structure-function relationships of neuronal circuits is crucial for unraveling how the brain achieves efficient information transfer. In specific brain regions, like the hippocampus, neurons are organized in lay...
Enhanced osteogenic differentiation in hyaluronic acid methacrylate (HAMA) matrix: a comparative study of hPDC and hBMSC spheroids for bone tissue engineering [0.03%]
透明质酸衍生物水凝胶微球递送人源间充质干细胞类器官用于骨组织再生修复的体外研究
Ane Albillos Sanchez,Filipa Castro Teixeira,Paula Casademunt et al.
Ane Albillos Sanchez et al.
Bone tissue engineering (BTE) seeks to overcome the limitations of traditional bone repair methods, such as autografts and allografts, which are often limited by availability, donor-site morbidity, immune rejection, and infection risks. Rec...
Ran Wang,Hangyu Zhang,Shijun Li et al.
Ran Wang et al.
The vascular tissue, as an integral component of the human circulatory system, plays a crucial role in retaining normal physiological functions within the body. Pathologies associated with the vasculature, whether direct or indirect, also c...
Bioinks for engineering gradient-based osteochondral and meniscal tissue substitutes: a review [0.03%]
用于工程梯度型骨软骨和半月板组织替代物的生物墨水：综述
Mahdieh Heydarigoojani,Maryam Farokhi,Sara Simorgh
Mahdieh Heydarigoojani
Gradient tissues are anisotropic structure with gradual transition in structural and biological properties. The gradient in structural, mechanical and biochemical properties of osteochondral and meniscal tissues play a major role in definin...
Recent trends in embedded 3D bioprinting of vascularized tissue constructs [0.03%]
嵌入式3D生物打印血管组织的最新趋势
Won-Woo Cho,Wonbin Park,Dong-Woo Cho
Won-Woo Cho
3D bioprinting technology offers significant advantages in the fabrication of tissue and organ structures by allowing precise layer-by-layer patterning of cells and various biomaterials. However, conventional bioinks exhibit poor mechanical...
Rational design of 3D-printed scaffolds for breast tissue engineering using structural analysis [0.03%]
基于结构分析的乳房组织工程三维打印支架的理性设计研究
Sharon Leigh Kracoff-Sella,Idit Goldfracht,Asaf Silverstein et al.
Sharon Leigh Kracoff-Sella et al.
Best cosmetic outcomes of breast reconstruction using tissue engineering techniques rely on the scaffold architecture and material, which are currently both to be determined. This study suggests an approach for a rational design of breast-s...
Collagen silver-doped hydroxyapatite scaffolds reinforced with 3D printed frameworks for infection prevention and enhanced repair of load-bearing bone defects [0.03%]
负载型骨缺损感染预防及修复增强的胶原蛋白掺银羟基磷灰石支架与3D打印框架复合材料
Katelyn J Genoud,Joanna M Sadowska,Rachael N Power et al.
Katelyn J Genoud et al.
Osteomyelitis, a severe bone infection, is an extremely challenging complication in the repair of traumatic bone defects. Furthermore, the use of long-term high-dose antibiotics in standard treatment increases the risks of antibiotic resist...