A novel solution for real-time in-situ cell distribution monitoring in 3D bioprinting via fluorescence imaging [0.03%]
利用荧光成像实现3D生物打印中实时原位细胞分布监测的新方法
Alessandro Margarita,Simone Giovanni Gugliandolo,Silvia Santoni et al.
Alessandro Margarita et al.
3D bioprinting is rapidly evolving as a transformative technology for constructing biological tissues with precise cell and bioink placement. However, ensuring the quality and viability of bioprinted structures presents significant challeng...
Light-based multi-material bioprinting of vascularised adipose tissue for breast fatty tissue engineering [0.03%]
用于乳房脂肪组织工程的血管化脂肪组织的光基多材料生物打印技术
Nina Hedemann,Alexander Thomas,Nils Tribian et al.
Nina Hedemann et al.
Reconstructive surgery following breast cancer ablation is a surgical gold standard and of increasing importance, but current options comprising autogenous fatty tissue transfer and artificial soft tissue implants are inferior. With the adv...
Advancing regenerative medicine: the Aceman System's pioneering automation and machine learning in mesenchymal stem cell biofabrication [0.03%]
推进再生医学：Aceman系统在间充质干细胞生物制造中对自动化和机器学习的开创性应用
Kai Zhu,Yi Ding,Yuqiang Chen et al.
Kai Zhu et al.
Mesenchymal stem cells (MSCs) are pivotal in advancing regenerative medicine; however, the large-scale production of MSCs for clinical applications faces significant challenges related to efficiency, cost, and quality assurance. We introduc...
Jishizhan Chen
Jishizhan Chen
Organoids have emerged as powerful tools in biomedical research, providing essential models for studying disease mechanisms, drug screening, and personalized medicine. However, most current organoid systems lack mechanical stimuli that are ...
Acetylcholine-loaded nanoparticles protect against doxorubicin-induced toxicity in in vitro cardiac spheroids [0.03%]
装载乙酰胆碱的纳米颗粒可保护离体心脏球体免受阿霉素诱导的毒性反应
Clara Liu Chung Ming,Runali Patil,Ahmed Refaat et al.
Clara Liu Chung Ming et al.
Doxorubicin (DOX) is widely used in chemotherapy, yet it significantly contributes to heart failure-associated death. Acetylcholine (ACh) is cardioprotective by enhancing heart rate variability and reducing mitochondrial dysfunction and inf...
Advancing extrusion-based embedded 3D bioprinting via scientific, engineering, and process innovations [0.03%]
通过科学、工程和工艺创新推进基于挤出的嵌入式3D生物打印技术
Ezgi Bakirci,Ali Asghari Adib,Syed Faaz Ashraf et al.
Ezgi Bakirci et al.
Extrusion-based embedded 3D bioprinting, where bioinks and biomaterials are extruded within a support bath, has greatly expanded the achievable tissue architectures and complexity of biologic constructs that can be fabricated. However, sign...
Advances in biofabrication and simulation strategies for gut-on-a-chip [0.03%]
器官芯片中的肠道模型的生物打印和仿真策略进展
Ke Wang,Yushen Wang,Junlei Han et al.
Ke Wang et al.
Biomimetic gut models show promise for enhancing our understanding of intestinal disorder pathogenesis and accelerating therapeutic strategy development. Current in vitro models predominantly comprise traditional static cell culture and ani...
Support-less 3D bioceramic/extracellular matrix printing in sanitizer-based hydrogel for bone tissue engineering [0.03%]
基于消毒剂的水凝胶中无支撑三维生物陶瓷/细胞外基质印刷用于骨组织工程
Siwi Setya Utami,Naren Raja,Jueun Kim et al.
Siwi Setya Utami et al.
To meet the growing demand for bone scaffolds, 3D printing has made significant advancements in bone tissue engineering. However, the materials used must closely mimic the biological components and structural characteristics of natural bone...
Chia-Tse Shih,Huan-Jun Guo,Chih-Hsin Shih et al.
Chia-Tse Shih et al.
Drug screening is an indispensable procedure in drug development and pharmaceutical research. For cell-based drug testing, cells were treated with compounds at different concentrations, and their responses were measured to assess the compou...
Real-time assessment of cell concentration and viability onboard a syringe using dielectric impedance spectroscopy for extrusion bioprinting [0.03%]
基于电介质阻抗谱的实时细胞浓度和活力测定用于挤出式生物打印中的移液管内检测
Alicia Adina Matavosian,Alexandra Caitlin Griffin,Didarul B Bhuiyan et al.
Alicia Adina Matavosian et al.
Bioprinting produces personalized, cell-laden constructs for tissue regeneration through the additive layering of bio-ink, an injectable hydrogel infused with cells. Currently, bioprinted constructs are assessed for quality by measuring cel...