Chen Chen,Paulus G M Jochems,Lucia Salz et al.
Chen Chen et al.
Investigation of diseases of the bile duct system and identification of potential therapeutic targets are hampered by the lack of tractable in vitro systems to model cholangiocyte biology. Here, we show a step-wise method for the differenti...
Simulations of 3D bioprinting: predicting bioprintability of nanofibrillar inks [0.03%]
纳米原纤维墨水的三维生物打印仿真：预测可打印性
Johan Göhl,Kajsa Markstedt,Andreas Mark et al.
Johan Göhl et al.
3D bioprinting with cell containing bioinks show great promise in the biofabrication of patient specific tissue constructs. To fulfil the multiple requirements of a bioink, a wide range of materials and bioink composition are being develope...
Lise De Moor,Idriz Merovci,Sarah Baetens et al.
Lise De Moor et al.
Overcoming the problem of vascularization remains the main challenge in the field of tissue engineering. As three-dimensional (3D) bioprinting is the rising technique for the fabrication of large tissue constructs, small prevascularized bui...
Pre-set extrusion bioprinting for multiscale heterogeneous tissue structure fabrication [0.03%]
预设挤出式生物打印实现多尺度异质组织结构制造
Donggu Kang,Geunseon Ahn,Donghwan Kim et al.
Donggu Kang et al.
Recent advances in three-dimensional bioprinting technology have led to various attempts in fabricating human tissue-like structures. However, current bioprinting technologies have limitations for creating native tissue-like structures. To ...
Microfluidic system for modelling 3D tumour invasion into surrounding stroma and drug screening [0.03%]
三维肿瘤向周围间质入侵的微流控模型及药物筛选系统
Zhichang Du,Shengli Mi,Xiaoman Yi et al.
Zhichang Du et al.
Tumour invasion into the surrounding stroma is a critical step in metastasis, and it is necessary to clarify the role of microenvironmental factors in tumour invasion. We present a microfluidic system that simulated and controlled multi-fac...
Bio-resin for high resolution lithography-based biofabrication of complex cell-laden constructs [0.03%]
基于光刻的高分辨率生物制造复杂细胞负载结构的生物树脂
Khoon S Lim,Riccardo Levato,Pedro F Costa et al.
Khoon S Lim et al.
Lithography-based three-dimensional (3D) printing technologies allow high spatial resolution that exceeds that of typical extrusion-based bioprinting approaches, allowing to better mimic the complex architecture of biological tissues. Addit...
Photolithographic-stereolithographic-tandem fabrication of 4D smart scaffolds for improved stem cell cardiomyogenic differentiation [0.03%]
用于改善干细胞心肌分化智能支架的光刻-立体光刻连续制造技术
Shida Miao,Haitao Cui,Margaret Nowicki et al.
Shida Miao et al.
4D printing is a highly innovative additive manufacturing process for fabricating smart structures with the ability to transform over time. Significantly different from regular 4D printing techniques, this study focuses on creating novel 4D...
Self-assembled human osseous cell sheets as living biopapers for the laser-assisted bioprinting of human endothelial cells [0.03%]
人骨细胞片作为活生物纸用于激光辅助打印人体内皮细胞
F Kawecki,W P Clafshenkel,F A Auger et al.
F Kawecki et al.
A major challenge during the engineering of voluminous bone tissues is to maintain cell viability in the central regions of the construct. In vitro prevascularization of bone substitutes relying on endothelial cell bioprinting has the poten...
Xinda Li,Libiao Liu,Xinzhi Zhang et al.
Xinda Li et al.
Artificial blood vessels must be strong, flexible, and must not lead to blockage after implantation. It is therefore important to select an appropriate fabrication process for products to meet these requirements. This review discusses the c...
Matrix stiffness and tumor-associated macrophages modulate epithelial to mesenchymal transition of human adenocarcinoma cells [0.03%]
基质刚度和肿瘤相关巨噬细胞调控人腺癌上皮间质转化
Marta Alonso-Nocelo,Theresa M Raimondo,Kyle H Vining et al.
Marta Alonso-Nocelo et al.
The tumor microenvironment (TME) is gaining increasing attention in oncology, as it is recognized to be functionally important during tumor development and progression. Tumors are heterogeneous tissues that, in addition to tumor cells, cont...