Joanne E Curran,Peter J Meikle,John Blangero
Joanne E Curran
"New high-dimensional canonical lipid phenotyping methods … are coming together to suggest a new paradigm for lipid gene discovery that is likely to be more successful than prior efforts." ...
T Hang Nghiem-Rao,Shailendra B Patel
T Hang Nghiem-Rao
The cholesterol molecule is at the center of the pathophysiology of many vascular diseases. Whole-body cholesterol pools are maintained by a balance of endogenous synthesis, dietary absorption and elimination from our bodies. While the cell...
Sphingolipid regulators of cellular dysfunction in Type 2 diabetes mellitus: a systems overview [0.03%]
二型糖尿病细胞功能障碍的鞘脂调节因子：系统综述
Jessica S Ross,Sarah B Russo,Georgia C Chavis et al.
Jessica S Ross et al.
Climbing obesity rates have contributed to worldwide increases in obesity-associated diseases, including the metabolic syndrome and Type 2 diabetes mellitus (T2DM). Sphingolipids, an important class of structural and signaling lipids, have ...
Effects of Armolipid Plus on small dense LDL particles in a sample of patients affected by familial combined hyperlipidemia [0.03%]
一种降脂膳食补充剂对家族性混合型高脂血症患者次优LDL颗粒的影响：一项随机对照试验
Marco Gentile,Ilenia Calcaterra,Alfonso Strazzullo et al.
Marco Gentile et al.
Aim: The aim of this study was to test small dense LDL changes with Armolipid Plus treatment in patients with familial combined hyperlipidemia (FCHL). Met...
Management of lipoprotein X and its complications in a patient with primary sclerosing cholangitis [0.03%]
原发性硬化性胆管炎患者脂蛋白X及其并发症的管理
Eric J Brandt,Shane M Regnier,Edward Ky Leung et al.
Eric J Brandt et al.
Lipoprotein X (LpX) is an abnormal lipoprotein found in conditions such as lecithin:cholesterol acyltransferase deficiency and cholestatic states (e.g., primary biliary cirrhosis and primary sclerosing cholangitis). Management of severe hyp...
Oxidized metabolites of linoleic acid as biomarkers of liver injury in nonalcoholic steatohepatitis [0.03%]
用于非酒精性脂肪肝病肝损伤标志物的γ-亚麻酸氧化代谢产物研究
Nicola Santoro,Sonia Caprio,Ariel E Feldstein
Nicola Santoro
The rising prevalence of obesity in the last few decades has been accompanied by an increase in nonalcoholic fatty liver disease (NAFLD). NAFLD encompasses a spectrum of liver pathology from isolated hepatic steatosis to steatohepatitis and...
Arthi Thirumalai,Katya B Rubinow,Stephanie T Page
Arthi Thirumalai
Testosterone prescriptions have risen steadily and sharply in the USA despite a lack of clear understanding of the relationship between androgens and cardiovascular disease. In men with increasing age, testosterone levels decline and cardio...
The ACCORD-Lipid study: implications for treatment of dyslipidemia in Type 2 diabetes mellitus [0.03%]
ACCORD-Lipid研究：治疗2型糖尿病患者血脂异常的启示
Marshall Elam,Laura Lovato,Henry Ginsberg
Marshall Elam
Patients with Type 2 diabetes mellitus (T2DM) are at high risk of developing cardiovascular disease (CVD). Treatment of diabetic dyslipidemia, comprised mainly of hypertriglyceridemia, and low HDL-C, with either statin or fibrate monotherap...
James L McManaman
James L McManaman
Lipids, primarily triglycerides, are major milk constituents of most mammals, providing a large percentage of calories, essential fatty acids and bioactive lipids required for neonatal growth and development. To meet the caloric and nutriti...