Inconsistent terminology in rodent anatomy hinders appropriate blood sampling in laboratory animal science: A review of blood sampling techniques on the head of mice [0.03%]
啮齿动物解剖术语不一致妨碍了实验动物科学中的适当采血:关于小鼠头部采血技术的综述
Malan Štrbenc
Malan Štrbenc
Blood sampling is often performed during animal studies. This is more challenging in mice than in larger animal species owing to their size and lack of blood vessel visibility. Guidelines for blood sampling in mice and papers on animal welf...
Moving from guideline recommendations to practical, reasonable proposals: Biosafety considerations, breeding performance and challenges during specific pathogen-free animal facility enlargement [0.03%]
从指导建议到实际可行提议的转变:无特定病原体动物设施扩建过程中的生物安全考量、繁育性能及挑战
Maschi Fabricio,Laborde Juan,Carriquiriborde Martín et al.
Maschi Fabricio et al.
Extending an existing animal facility is a challenging process that requires consideration of both engineering and biological aspects. In this sense, integration with ongoing activities must not alter the animals' microbiological condition ...
The advisory body on animal ethics of a global pharmaceutical company: A global organization to address ethical and societal concerns about animal use [0.03%]
国际药品企业的动物伦理顾问机构——一个应对动物使用伦理和社会问题的全球性组织
Juliette Schmitt-Lemaître,Nicolas Dudoignon,Edith Stuyven et al.
Juliette Schmitt-Lemaître et al.
How do you promote ethical principles on a global scale regarding the use of animals for scientific purposes within a global pharmaceutical company like Sanofi? In 2017, the Advisory Body on Animal Ethics (ABAE) was created to harmonize ani...
Retrospective descriptive report comparing access systems to refine intravenous self-administration in rats [0.03%]
回顾性描述报告:比较取用系统以精炼大鼠静脉自我给药
José G Lozeman-van t Klooster,Heidi Mb Lesscher
José G Lozeman-van t Klooster
For operant self-administration, permanent intravenous cannulas need to remain open and operational for months without infections or blockages. Here, we report retrospectively on our experiences and observations using different access syste...
Comprehensive review of animal models in diabetes research using chemical agents [0.03%]
化学试剂在糖尿病研究中动物模型的全面回顾
Sermin Algul,Oguz Ozcelik
Sermin Algul
Diabetes mellitus, characterized by insufficient insulin secretion and impaired insulin efficacy, disrupts carbohydrate, protein, and lipid metabolism. The global diabetic population is expected to double by 2025, from 380 million, posing a...
Biological adaptation to a germ-free environment should not be mistaken as a burden for animals [0.03%]
生物体适应无菌环境是一种适应性状而非宿主负担
Silvia Bolsega,André Bleich,Martina Dorsch et al.
Silvia Bolsega et al.
The effectiveness of educational workshops in improving the knowledge and attitude of attendees in laboratory animal science: A pre- and post-intervention design in Iran [0.03%]
伊朗一项关于教育 workshop 对改善实验动物科学从业人员知识和态度之有效性的前瞻和干预后调查设计研究
Siavash Ahmadi-Noorbakhsh,Jila Sadighi,Zahra Hatami et al.
Siavash Ahmadi-Noorbakhsh et al.
The knowledge and attitude of researchers can affect the validity of laboratory animal (LAN) research. However, studies show that not all researchers possess the required knowledge and appropriate attitude for performing valid research on a...
Case report: C57BL/6NTac and C57BL/6NCrl mice displaying neurological signs after deworming with ivermectin [0.03%]
案例报告:伊维菌素驱虫后出现神经症状的C57BL/6NTac和C57BL/6NCrl小鼠
M Eriksson,S Nylén
M Eriksson
For over 40 years, ivermectin has served as an effective anti-parasitic drug used in human and veterinary medicine. In laboratory animal facilities it is used prophylactically or therapeutically to maintain the health status of the colony o...
Reusing zebrafish facility equipment: Planning, investment and what we have learned [0.03%]
斑马鱼设施设备的重复使用:规划、投资及我们的经验教训
Olga M Fernández-Rodriguez,Emilio Cortés,Pablo Pelegrín et al.
Olga M Fernández-Rodriguez et al.
The purpose of this study is to provide a detailed account of our successful experience in establishing a functional zebrafish holding facility by repurposing materials from a previous installation. On the eve of the start-up of our new ani...
Pre-immunization of diet-induced obese male mice with inactivated pathogens increases power in a liraglutide intervention study [0.03%]
预先用灭活病原体免疫饮食诱导的肥胖雄性小鼠可增强利拉格列汀干预研究的功效
Caroline Falkenberg,Dorte B Sørensen,Camilla Hf Hansen et al.
Caroline Falkenberg et al.
Pre-immunization with inactivated antigens has been developed as an alternative to the use of 'dirty' mice, which in contrast to specific pathogen free (SPF) mice, harbour a range of pathogens. Within certain research areas, such mice are c...