FELASA recommendations for continuing professional development for professionals involved in animal research [0.03%]
实验动物科学协会的从业人员继续教育指导建议——以参与动物研究的专业人员为例
Magda João Castelhano-Carlos,Marcel Gyger,Chris Van Ginneken et al.
Magda João Castelhano-Carlos et al.
A continuing professional development (CPD) process should be implemented in all organisations involved in animal research to ensure professionals stay up to date with scientific advancements, best practices and regulations regarding animal...
Sex-specific histoarchitecture and functional correlation of the rat thyroid gland [0.03%]
大鼠甲状腺的性别特异性组织结构及其与功能的相关性研究
Ivan Milošević,Anja Nikolić,Emilija Nićković et al.
Ivan Milošević et al.
The thyroid gland's proper function is essential for controlling the metabolism, which varies to some extent between the sexes, thus maintaining the homeostasis. This research aimed to investigate differences in the histological structure a...
One size does not fit all: Guidelines for designing a score sheet for animal experiments - eight essential steps [0.03%]
放之四海而皆准的方案并不存在:设计动物实验评分表的八项指导原则及关键步骤
Michaela Thallmair,María J Duque-Correa,Maike Heimann et al.
Michaela Thallmair et al.
The EU Directive 2010/63 on the protection of animals used for scientific purposes, as well as the Swiss Animal Welfare Legislation, demand monitoring and documentation of specific aspects of an animal experiment, including welfare-related ...
Clinical evaluation of intranasal midazolam and alfaxalone for induction of anaesthesia in rabbits [0.03%]
临床评估咪达唑仑和 Alfaxalone鼻内给药用于诱导家兔麻醉的效果
Jennifer Hiekel,Peter Wm Kronen,Karina Klein
Jennifer Hiekel
The aim of this experimental, descriptive study was to evaluate feasibility, safety and side effects of alfaxalone and midazolam by intranasal instillation for anaesthesia induction in rabbits. We included 26, healthy, female New Zealand Wh...
Shelved cages impact affective behavior in Sprague Dawley rats - implications for animal welfare [0.03%]
笼架搁置影响大鼠情感行为-对动物福利的影响
Logan J Bigelow,Emily K Pope,Clare Pl Lee et al.
Logan J Bigelow et al.
Laboratory animal welfare has received increasing attention in recent years as housing protocols move toward favoring environments that allow natural behaviors. Within this study, the effects of housing male and female Sprague Dawley rats i...
Advancing ethical standards in Göttingen Minipigs studies: The feasibility and reliability of Vascular Access Buttons™ [0.03%]
戈廷根迷你猪血管通路按钮的可行性和可靠性的伦理标准研究
Mèlanie Reijnaers,Joelle van Dijk,Gabry Warmels et al.
Mèlanie Reijnaers et al.
The use of Vascular Access Buttons™ (VABs) is gaining traction in animal research as a less invasive alternative to traditional venipuncture methods and a superior option compared with existing alternatives, such as vascular access ports (...
Cardiopulmonary, echodopplercardiographic and cardiac output effects of isoflurane anaesthesia in male sheep [0.03%]
异氟醚麻醉对公羊心肺、心脏超声以及心排血量的影响
Rauane Sousa de Moura,Beatriz Kawamura Rodrigues,Daianny Pires de Freitas et al.
Rauane Sousa de Moura et al.
Eight male Dorper sheep were anesthetized with isoflurane to evaluate the effects of anesthesia on cardiopulmonary parameters, echocardiographic variables and cardiac output (CO) using echocardiography methods compared with thermodilution. ...
Idiopathic hypereosinophilic syndrome in a female Sprague Dawley rat [0.03%]
一只雌性Sprague-Dawley大鼠的特发性高嗜酸性粒细胞综合症
Elizabeth Lavin,Morgan Shelton,Jeanine Peters-Kennedy et al.
Elizabeth Lavin et al.
An approximately 7.5-month-old female Sprague Dawley rat (Rattus norvegicus) housed in a research facility presented for skin lesions including multifocal crusting and hypotrichosis. On presentation the research rat was mildly underconditio...
Welfare complications in the male BN/Crl and RjHan:SD rat streptozotocin-induced diabetes models [0.03%]
链球菌毒素诱导的BN/Crl和RjHan:SD大鼠糖尿病模型的福利问题复杂性
Anni Tenhunen,Satu Mering,Hanna-Marja Voipio et al.
Anni Tenhunen et al.
The streptozotocin (STZ)-induced hyperglycaemic rat model is widely used in diabetes research, particularly for investigating diabetic retinopathy; however, animal welfare concerns are often underreported. This study evaluated welfare outco...