From exposure to evidence: The present and future of rodent surgical training in laboratory animal science [0.03%]
从接触至证据：实验动物科学中啮齿类动物手术训练的现状及未来方向
Diego Celdran-Bonafonte,Petra Seebeck
Diego Celdran-Bonafonte
Surgical training remains one of the most consequential yet historically underexamined components of laboratory animal science (LAS). While advances in anesthesia, analgesia, asepsis, and oversight have improved welfare and scientific rigor...
Decision trees for managing genetically burdened laboratory animal lines under Directive 2010/63/EU [0.03%]
欧盟指令2010/63/EU指导下的转基因实验动物管理决策树方法
Myhailo Reshetnykov,Jan Baumgart
Myhailo Reshetnykov
The breeding and maintenance of genetically modified laboratory animal lines with a harmful phenotype (hereafter referred to as "genetically burdened lines")-that is, lines in which pain, suffering, distress, or lasting harm may arise as an...
Species-specific housing and routine procedures for spiny mice (Acomys) maintained in large individually ventilated cages [0.03%]
刺毛鼠（Acomys）在大型个体通风笼盒中的特定物种饲养和常规操作规程
Antonio Tomasso,Aida Rodrigo Albors,Sofia Ferreira-Gonzalez et al.
Antonio Tomasso et al.
Spiny mice (Acomys spp.) are increasingly used in biomedical research owing to their unique physiological properties and ability to regenerate tissues, yet standardized laboratory housing conditions are largely based on mouse or rat models ...
FELASA's accreditation for high-quality training in laboratory animal sciences [0.03%]
实验动物科学高质量培训的FELASA认证政策文件
Chris Van Ginneken,Magda João Castelhano-Carlos,Julia Steidle et al.
Chris Van Ginneken et al.
The Federation of European Laboratory Animal Science Associations (FELASA) has played a pivotal role in ensuring high-quality education and training in laboratory animal sciences via accrediting courses. FELASA has revised its accreditation...
Long-term eradication of the chytrid fungus Batrachochytrium dendrobatidis from a large Xenopus laevis husbandry [0.03%]
两栖动物模型动物Xenopus laevis养殖场长期根除蛙壶菌(Batrachochytrium dendrobatidis)
Ulrike Teichmann,Sarah Kimmina
Ulrike Teichmann
The chytrid fungus Batrachochytrium dendrobatidis (BD) poses a serious threat to amphibian species worldwide. BD infects keratinocytes of the skin and interferes with their physiological barrier function. The African clawed frog Xenopus lae...
Reporting and transparency in laboratory animal science: Past achievements, present concerns and future directions [0.03%]
实验动物科学研究中的报告和透明度：过去的成绩、现在的担忧以及未来的方向
Penny S Reynolds,Esther J Pearl
Penny S Reynolds
Transparent reporting of animal research is both a scientific and ethical imperative and is linked to both research quality and the principles of Replacement, Reduction, and Refinement (3Rs). Persistent concerns about poor reproducibility, ...
Complete Freund's adjuvant in laboratory animals: Reported welfare-relevant outcomes and alternatives-a scoping review [0.03%]
完成弗氏佐剂在实验动物中的应用：相关福利结局及替代措施的系统综述
Valerie Hungerbühler,Agathe Verhulst,Cristian Berce et al.
Valerie Hungerbühler et al.
Complete Freund's adjuvant (CFA) is used in laboratory animals to stimulate strong immune responses. However, it can cause persistent local inflammation and tissue damage, raising welfare concerns. This scoping review aimed to (i) assess ho...
Can trained behavior serve as tool for welfare assessment? A pilot study in a cancer model with Wistar rats [0.03%]
训练行为能否作为评估福利的指标？一项癌症模型下的韦斯蒂大鼠试点研究
Jennifer Mein,Marie-Luise H H Ranner-Hafferl,Dilyana B Mangarova et al.
Jennifer Mein et al.
This pilot study investigates whether trained behavioral tasks may serve as early, non-invasive indicators of distress in high-severity disease models in laboratory rats. Therefore, six Wistar rats in a diethylnitrosamine-induced hepatocell...
Standardized surgical access to the porcine temporomandibular joint: Anatomical basis for translational research [0.03%]
标准化的猪下颌关节手术入路：转化研究的解剖学基础
Jean-François Guignardat,Romain Nicot,Thomas Hubert et al.
Jean-François Guignardat et al.
Temporomandibular disorders affect about 12% of the industrialized population, and their complex management often results in recurrence or treatment failure. Among animal models, the pig is particularly relevant owing to its anatomical simi...