A review of the comparative anatomy of the domestic pig (Sus scrofa domestica) and its relevance to translational research in abdominal transplantation [0.03%]
家猪( Sus scrofa domestica)的比较解剖学回顾及其在腹部移植转化研究中的相关性
Dylan R Barnett,Rohan Bhattacharjya,Shantanu Bhattacharjya
Dylan R Barnett
This narrative review summarizes and synthesizes the current literature regarding the comparative anatomy of pigs and humans, focusing on organ systems commonly involved in abdominal transplantation with the aim of supporting the safe and e...
Carprofen increases the risk of anastomotic leakage in a mouse model of Roux-en-Y gastric bypass [0.03%]
卡马西平增加RYGB小鼠模型吻合口漏风险
Philip Claus,Rebecca Springer,Christoph Otto et al.
Philip Claus et al.
Anastomotic leakage following intestinal surgery in a murine Roux-en-Y gastric bypass (RYGB) model is usually fatal. Carprofen, a commonly used non-steroidal anti-inflammatory drug (NSAID) for postoperative analgesia in rodents, has been li...
Sarah E Wolfensohn,Vera Baumans,F Josef van der Staay et al.
Sarah E Wolfensohn et al.
Better animal welfare is essential for better animal-based science. Poor welfare induces stress (and vice versa), which in turn can affect or even severely confound research results. To ensure the validity of scientific results, those who w...
Transcranial direct current stimulation (tDCS) in conscious mice: a refined method for repetitive applications without restraint [0.03%]
清醒小鼠经颅直流电刺激(tDCS):无需固定反复施加的精炼方法
Nora Rautenberg,Stefan Johannes Blaschke,Susan Vlachakis et al.
Nora Rautenberg et al.
Transcranial direct current stimulation (tDCS) for painless, non-invasive brain stimulation is a promising approach to enhance recovery after stroke. However, the precise molecular and cellular mechanisms underlying the effects of tDCS rema...
Research sense: Incorporating animals' sensory capacities in animal care and study design [0.03%]
研究感知能力:在动物护理和实验设计中纳入动物的感觉能力
Mal Graham,Bob Fischer
Mal Graham
No systematic procedures exist to ensure that differences in animal sensory capacities are accounted for in experimental design and ethical review processes. This oversight can compromise both scientific validity and animal welfare. This re...
Widespread antimicrobial use in laboratory rodent vivaria in North America revealed by a cross-sectional survey of American College of Laboratory Animal Medicine certified veterinarians [0.03%]
一项针对美国实验动物医学协会认证兽医的横断面调查显示北美实验动物房内普遍存在抗生素使用情况
Rebbecca S Wilcox,Marc S Marenda,Joanne M Devlin et al.
Rebbecca S Wilcox et al.
Antimicrobial resistance (AMR) is a major global threat to human health, animal welfare and sustainable development. Whilst resistance can arise naturally, inappropriate antimicrobial exposure accelerates its emergence. Recognizing this ris...
FELASA recommendations for continuing professional development for professionals involved in animal research [0.03%]
实验动物科学协会的从业人员继续教育指导建议——以参与动物研究的专业人员为例
Magda João Castelhano-Carlos,Marcel Gyger,Chris Van Ginneken et al.
Magda João Castelhano-Carlos et al.
A continuing professional development (CPD) process should be implemented in all organisations involved in animal research to ensure professionals stay up to date with scientific advancements, best practices and regulations regarding animal...
Sex-specific histoarchitecture and functional correlation of the rat thyroid gland [0.03%]
大鼠甲状腺的性别特异性组织结构及其与功能的相关性研究
Ivan Milošević,Anja Nikolić,Emilija Nićković et al.
Ivan Milošević et al.
The thyroid gland's proper function is essential for controlling the metabolism, which varies to some extent between the sexes, thus maintaining the homeostasis. This research aimed to investigate differences in the histological structure a...
One size does not fit all: Guidelines for designing a score sheet for animal experiments - eight essential steps [0.03%]
放之四海而皆准的方案并不存在:设计动物实验评分表的八项指导原则及关键步骤
Michaela Thallmair,María J Duque-Correa,Maike Heimann et al.
Michaela Thallmair et al.
The EU Directive 2010/63 on the protection of animals used for scientific purposes, as well as the Swiss Animal Welfare Legislation, demand monitoring and documentation of specific aspects of an animal experiment, including welfare-related ...
Clinical evaluation of intranasal midazolam and alfaxalone for induction of anaesthesia in rabbits [0.03%]
临床评估咪达唑仑和 Alfaxalone鼻内给药用于诱导家兔麻醉的效果
Jennifer Hiekel,Peter Wm Kronen,Karina Klein
Jennifer Hiekel
The aim of this experimental, descriptive study was to evaluate feasibility, safety and side effects of alfaxalone and midazolam by intranasal instillation for anaesthesia induction in rabbits. We included 26, healthy, female New Zealand Wh...