A customised combination of environmental enrichment reduces aggression in CD-1 male mice [0.03%]
定制化的环境丰富度结合方法可以降低CD-1雄性小鼠的攻击行为
Amy Veness,Christophe Galichet,Sian Murphy et al.
Amy Veness et al.
Murine aggression has profound implications on animal welfare and husbandry. This report examines how three distinct combinations of environmental enrichment - wheel, igloo and tunnel; wheel, igloo, and tunnel with nesting; and tunnel with ...
Michaela Thallmair,Paulin Jirkof
Michaela Thallmair
Inflammatory bowel diseases (IBDs) are a major health burden, and incidence as well as prevalence have increased over the last decades. Colitis animal models are used to explore the underlying pathogenesis of and therapeutic options for IBD...
The (re)turn of the 3Rs: an inquiry into the normative nature of Russell and Burch's principles of humane experimental technique - their misunderstanding, reform and implementation through an ethics tool [0.03%]
（重新）审视3R原则：对Russell和Burch的实验动物人道技术原则之规范本质及其误解、改革与通过伦理工具实施进行探究
Herwig Grimm,Marc Dusseldorp
Herwig Grimm
The 3Rs strongly shape the practice of laboratory animal use, as well as related policies worldwide. This success should not obscure the fact that implementing the 3Rs comes with challenges. A major problem is that it is fundamentally uncle...
Evaluating cervical dislocation methods, without using tension on the tail, for humanely killing adult laboratory mice [0.03%]
评估用于杀死实验小鼠的人道处死方法——无需拉伸尾部的颈椎脱位法评估
Antony Davidge,Flaviu Bulat,Aude Vernet
Antony Davidge
Cervical dislocation (CD) is a widely used method worldwide for humanely killing adult laboratory mice in accordance with national legislation, such as the Animals (Scientific Procedures) Act 1986 in the UK. However, concerns have been rais...
Teaching experimental design: outputs from the FELASA Working Group [0.03%]
欧洲实验室动物科学协会工作组的教学和实验设计成果
Derek Fry,Manuel Berdoy,Monica Forni et al.
Derek Fry et al.
Good education and training for scientists undertaking animal experiments is important for providing understanding of key issues in experimental design (ED) and for alleviating continuing concerns about the conduct of animal and in vitro re...
Sex and strain differences in the micropipette-guided drug administration (MDA) method in mice [0.03%]
小鼠微吸管引导给药法的性别和品系差异研究
Sarah Steiner,Olga Krzyzaniak,Frida A M Nilsson et al.
Sarah Steiner et al.
To provide an alternative to oral gavage for per os treatments in laboratory mice, we have recently developed and introduced the micropipette-guided drug administration (MDA) method. This procedure is based on the presentation of a palatabl...
Compassion fatigue in laboratory animal personnel: a bibliometric analysis of global trends [0.03%]
实验动物人员同情疲劳的全球趋势计量学分析
John K Chipangura
John K Chipangura
Laboratory animal personnel face enormous pressures such as workload, conflicts, deadlines, lack of psychological support, and ethical dilemmas. These pressures are often due to the need to balance scientific objectives, ethical responsibil...
Johannes Schenkel,Stefan Nagel-Riedasch,Branko Zevnik et al.
Johannes Schenkel et al.
News from the EIC team [0.03%]
主编来信
Annemarie Lang,Paulin Jirkof,Josè Sanchez-Morgado et al.
Annemarie Lang et al.