Untargeted LC-MS/MS Profiling Identifies ST18 as a Novel Serum Marker for T2DM-Associated Depression [0.03%]
基于LC-MS/MS的无靶标代谢组学研究发现ST18作为T2DM相关抑郁的新血清标志物
Jiya Singh,Sabyasachi Bandyopadhyay,Atanu Sen et al.
Jiya Singh et al.
Depression is a prevalent but underdiagnosed comorbidity in type 2 diabetes mellitus (T2DM), intensifying disease burden and complicating metabolic management. Reliable biomarkers for early detection remain limited. This study aimed to iden...
Bayesian Secondary Reanalysis of Published Aggregate Data on Circulating Tumor DNA for Molecular Residual Disease Detection Across Cancer Types [0.03%]
基于血液循环肿瘤DNA检测各类癌症分子残留病灶的贝叶斯二次分析法再研究.published aggregate data
Shugo Yajima,Soichiro Yoshida,Wei Chen et al.
Shugo Yajima et al.
Background Circulating tumor DNA (ctDNA)-based molecular residual disease (MRD) testing may help estimate recurrence risk after treatment. We performed a Bayesian secondary reanalysis of published aggregate data to estimate prognostic and d...
Stability of Electrolytes in Whole Blood at Room Temperature Prior to Centrifugation: implications for Clinical Analysis [0.03%]
血液常温抗凝离心前电解质稳定性对临床分析的影响
Sayamon Janyapaisarn,Maneenooch Torngsawarng,Napaporn Inganuruksakul et al.
Sayamon Janyapaisarn et al.
Background/Objectives The pre-analytical stability of electrolytes in capped whole blood at room temperature remains uncertain due to limited studies and inconsistent findings. This study investigates electrolyte stability during delayed ce...
Comparison of Jaffe, Enzymatic, and Mass Spectrometric Methods for Creatinine Measurement in Protein-Positive and Hemoglobin-Positive Urine Samples [0.03%]
蛋白尿和血红蛋白阳性标本中肌酐测定的Jaffe法、酶法及质谱法比较研究
Gulsum Abuşoğlu,Mohammad Ahmad Bik,Firdevs Sak et al.
Gulsum Abuşoğlu et al.
Accurate measurement of urine creatinine is essential for evaluating renal function. Although the Jaffe and enzymatic methods are routinely applied in clinical laboratories, various urinary compounds can interfere with these assays. This st...
Limitations of spectrophotometry in the analysis of cerebrospinal fluid bilirubin [0.03%]
分光光度法在脑脊液胆红素分析中的局限性
Katherine Birch,Maria Squires,Miles Chapman et al.
Katherine Birch et al.
BackgroundCerebrospinal fluid (CSF) spectrophotometry is well-established in the UK for measuring CSF bilirubin and oxyhaemoglobin to aid in the diagnosis of subarachnoid haemorrhage. Although it is known that some antibiotics and large amo...
From interpretable NT-proBNP prediction to equitable laboratory stewardship [0.03%]
从可解释的NT-proBNP预测到公平的实验室管理政策制定
Rajesh Prasad Jayaswal,Shailendra Thapliyal,Rama Kumari Badyal et al.
Rajesh Prasad Jayaswal et al.
Susanna Reincke,Mirko Rehberg,Stefanie Stasek et al.
Susanna Reincke et al.
Context: Sclerostin inhibits bone formation via the WNT/β-catenin pathway and is a therapeutic target in osteoporosis. Antibodies against sclerostin are currently under investigation for the treatment of osteogenesis imp...
Population-Specific HOMA-IR Reference Ranges in Iraq: Defining Insulin Sensitivity in a Middle Eastern Cohort [0.03%]
伊拉克人群特异性的HOMA-IR参考范围：在中东人群中定义胰岛素敏感性
Mustafa Al-Bayaty,Mohammed Shamil,Ragheed Hussam Yousif
Mustafa Al-Bayaty
The homeostatic model assessment for insulin resistance (HOMA-IR) is one of the most commonly applied surrogate markers for the measurement of insulin resistance; however, the use of this metric does require sex-specific, age-specific, and ...