Calcium oscillations in mesenchymal stem cells, a control on cell cycle progression to influence cell fate towards proliferation or differentiation? [0.03%]
基质干细胞中的钙振荡通过调控细胞周期来影响细胞命运决定增殖还是分化？
Leslie A Vallet,Marina Sánchez-Petidier,Romain Fernandes et al.
Leslie A Vallet et al.
Background: Under regular culture conditions, mesenchymal stem cells (MSCs) exhibit cytosolic calcium concentration oscillations (Ca2+ oscillations), that change, especially in frequency, after the differentiation of the ...
Constraint-induced movement therapy combined with mesenchymal stem cell transplantation promotes myelination and functional recovery by inhibiting PRKCD/MEK/ERK pathway in hemiplegic cerebral palsy rats [0.03%]
constraint-induced运动疗法结合间充质干细胞移植通过抑制PRKCD/MEK/ERK通路促进脑瘫偏瘫模型大鼠的髓鞘化和功能恢复
Xiaolin Guo,Liru Liu,Jie Luo et al.
Xiaolin Guo et al.
Background: The core problem of hemiplegic cerebral palsy (HCP) is upper limb motor deficits with high rates of disability. Given the shared goals of stem cell therapy and rehabilitation, this study investigated the syner...
Correction: High-throughput robotic isolation of human iPS cell clones reveals frequent homozygous induction of identical genetic manipulations by CRISPR-Cas9 [0.03%]
纠正：高通量机器人分离人类iPSC克隆揭示CRISPR-Cas9相同遗传操作频繁的同源诱导入 iPSC 克隆中的相同位点
Gou Takahashi,Minato Maeda,Kayoko Shinozaki et al.
Gou Takahashi et al.
Published Erratum
Stem cell research & therapy. 2025 Aug 20;16(1):445. DOI:10.1186/s13287-025-04564-3 2025
Multi-function of adipose-derived stem cells on gut disorder: from bench to bedside [0.03%]
基于脂肪干细胞的多功能性治疗肠病：从基础到临床
Jiatong Zhao,Shuzi Xin,Xiaohui Liu et al.
Jiatong Zhao et al.
Adipose-derived stem cells (ADSCs) are a specific type of mesenchymal stem cells (MSCs) obtained easily from adipose tissue (AT). Compared with MSCs, ADSCs are easier to obtain, have fewer ethical issues, and have a higher proliferative cap...
Harnessing TGF-β signaling to improve testicular organoid development from dissociated testicular cells [0.03%]
利用TGF-β信号通路改善分离睾丸细胞来源的睾丸类器官发育
Seyedeh-Faezeh Moraveji,Saiedeh Erfanian,Mohammad Hossein Ghanian et al.
Seyedeh-Faezeh Moraveji et al.
Background: Testicular organoids (TOs) have generated great interest in reproductive biology as a reliable experimental tissue model for pharmaco-toxicology studies and therapeutic applications. However, current TOs mostl...
MicroRNA-4516 in extracellular vesicles-derived mesenchymal stem cells suppressed integrin αV-mediated lung fibrosis [0.03%]
外泌体来源的间充质干细胞中的微小核糖核酸-4516通过抑制整合素αV介导的肺纤维化发挥抗纤维化作用
Issei Sumiyoshi,Shinsaku Togo,Junko Watanabe et al.
Issei Sumiyoshi et al.
Background: Idiopathic pulmonary fibrosis (IPF) is characterized by the recruitment of lung fibroblasts to sites within the lung interstitium, along with the differentiation of myofibroblasts induced by transforming growt...
Correction: DPSCs modulate synovial macrophage polarization and efferocytosis via PINK1/Parkin-dependent mitophagy [0.03%]
题图说明：DPSCs通过PINK1/Parkin依赖的线粒体自噬调节滑膜巨噬细胞极化和胞葬作用
Jinjin Ma,Xinyu Wang,Dalei Sun et al.
Jinjin Ma et al.
Published Erratum
Stem cell research & therapy. 2025 Aug 10;16(1):441. DOI:10.1186/s13287-025-04565-2 2025
Trained human bone marrow mesenchymal stem cells restore tissue immuno-microenvironment in fulminant hepatic failure mice [0.03%]
体外诱导的骨髓间充质干细胞修复急性肝衰竭免疫微环境的研究
Bingqi Li,Xiaofei Zeng,Jing Jiang et al.
Bingqi Li et al.
Background: Trained immunity with human bone marrow mesenchymal stem cells (hBMSC) is a promising approach to liver regeneration. This study aimed to clarify the trained-hBMSC (T-hBMSC) in restoring tissue immuno-microenv...
Mesenchymal stromal cells conditioned by peripheral blood mononuclear cells exert enhanced immunomodulation capacities and alleviate a model of Myasthenia Gravis [0.03%]
外周血单个核细胞条件培养的间充质基质细胞增强免疫调节功能并改善MG模型症状
Alexandra C Bayer,Natalia Pinzón,Axel You et al.
Alexandra C Bayer et al.
Background: Mesenchymal Stromal Cells (MSC) possess innate immunomodulatory properties, which can be significantly enhanced through co-culture with peripheral blood mononuclear cells (PBMC), making them attractive tools f...
HMGB1 as an emerging key modulator of bone remodeling: a narrative review [0.03%]
高迁移率族蛋白B1在骨代谢调节中的作用及机制
Jun Tang,Ming Li,Lin Huang
Jun Tang
Bone is a dynamic tissue that undergoes microdamage and requires remodeling to replace old bone matrix. This process demands a tight coupling between bone resorption and bone formation. Aberrant internal environment can decouple these proce...