Exploring the therapeutic potential of MSC-derived secretomes in neonatal care: focus on BPD and NEC [0.03%]
探究MSC来源的分泌组在新生儿护理中的治疗潜力:重点关注支气管肺发育不良和坏死性小肠ocolitis
Tasnim Azad,Feifeng Wu,Jueyi Mao et al.
Tasnim Azad et al.
Background: Every year, millions of infants are born prematurly, many of whom develop serious complications like bronchopulmonary dysplasia and necrotizing enterocolitis. Despite improvements in neonatal care, there are f...
Correction: Emodin-Enhanced hUC-MSC extracellular vesicles alleviate acute pancreatitis by targeting inflammation and pyroptosis [0.03%]
纠正:艾莫丁增强型hUC-MSC外泌体通过靶向炎症和细胞焦亡缓解急性胰腺炎
Xiong Liu,Xianwei Huang,Xiaodong Huang et al.
Xiong Liu et al.
Published Erratum
Stem cell research & therapy. 2025 Aug 29;16(1):477. DOI:10.1186/s13287-025-04566-1 2025
Donor-dependent regulation of type II and X collagen deposition by early modulation of miR-335-5p and miR-1246 during chondrogenic commitment [0.03%]
微小核糖核酸-335-5p和微小核糖核酸-1246调节软骨细胞分化中II型和X型胶原蛋白的表达依赖于供体基因型
Franziska L Breulmann,Silvia A Berger,Elena Della Bella et al.
Franziska L Breulmann et al.
Background: Identification of biomarkers to predict the risk of healing delays are of huge clinical interest since 10% of fracture patients progress to delayed or non-union. During endochondral ossification, which takes p...
Dafina Najwa Mohd Arizam,Fazlina Nordin,Azlina Ahmad et al.
Dafina Najwa Mohd Arizam et al.
This review provides an overview of the integrin signaling pathways and their roles in mesenchymal stem cell differentiation into adipocytes, chondrocytes, and osteoblasts. In these three differentiated cells, the cell extracellular matrix ...
Stem cell-based human embryo models: current knowledge and open questions [0.03%]
基于干细胞的人类胚胎模型:当前知识和开放问题
Margit Rosner,Stefanie Horer,Izabella Kiss et al.
Margit Rosner et al.
Recently, the research field revolving around the stem cell-based modeling of the human embryo gained particular momentum when the first integrated models were designed with the aim to recapitulate the development of the entire early human ...
From mitochondria to immune networks: new mesenchymal stem cell strategies to treat periodontitis [0.03%]
从中突质体到免疫网络:治疗牙周炎的新间充质干细胞策略
Xinyu Wang,Chengran Wang,Mei Ren et al.
Xinyu Wang et al.
Periodontitis is a chronic inflammatory disease that damages periodontal tissues and is mainly caused by immune dysfunction. Current treatments, such as mechanical debridement and adjunctive antimicrobial, work poorly; periodontal surgery b...
Menstrual blood-derived endometrial stem cells ameliorate neuroinflammation and apoptosis through JAK2/STAT3 signaling pathway in NPC1 mutant cell and mice [0.03%]
月经血源性子宫内膜干细胞通过JAK2/STAT3信号通路改善NPC1突变细胞和小鼠的神经炎症和凋亡
Lihong Guan,Keli Xu,Minlin Yang et al.
Lihong Guan et al.
Background: Niemann-Pick disease type C1 (NPC1) is caused by NPC1 gene mutations, resulting in Purkinje cell degeneration and death, glial cell activation, and progressive neurodegeneration. Menstrual blood-derived endome...
Antimicrobial peptide PK34 modification enhances the antibacterial and anti-inflammatory effects of bone-derived mesenchymal stem cells in Mycobacterium tuberculosis infection [0.03%]
抗菌肽PK34修饰增强骨髓间充质干细胞对结核杆菌感染的杀菌和抗炎作用
Xin-Yu He,Jia-Qi Wang,Yao Chen et al.
Xin-Yu He et al.
Background: New therapeutic strategies are needed to treat tuberculosis (TB). The antimicrobial peptide PK34 has a good ability to clear Mycobacterium tuberculosis (Mtb) and is not prone to drug resistance and adverse rea...
Cardioprotective effects of extracellular vesicles from hypoxia-preconditioned mesenchymal stromal cells in experimental pulmonary arterial hypertension [0.03%]
低氧预处理间充质基质细胞来源的细胞外囊泡在实验性肺动脉高压中的心保护作用
Renata Trabach Santos,Cássia Lisboa Braga,Maria Eduarda de Sá Freire Onofre et al.
Renata Trabach Santos et al.
Background: During pulmonary arterial hypertension (PAH), cardiac cells develop a hypertrophic and apoptosis-resistant phenotype. Mesenchymal stromal cell (MSC) therapy has been shown to mitigate pulmonary vascular remode...
Evaluation of stem/stromal cell transplantation safety and efficacy in children diagnosed with cerebral palsy: A systematic review and meta-analysis of randomized controlled trials [0.03%]
干细胞/间充质干细胞治疗脑瘫儿童安全性和有效性的系统评价和meta分析
Ronak Fatahi,Fatemeh Heydarpour,Sepehr Moradi Motlagh et al.
Ronak Fatahi et al.
Background: Cerebral palsy is a neurological disorder that affects both postnatal and prenatal children. It results from brain damage in the cerebral motor cortex. The three types of CP are spastic, dyskinetic, and mixed ...